ENSMUSG00000017390


Mus musculus

Features
Gene ID: ENSMUSG00000017390
  
Biological name :Aldoc
  
Synonyms : Aldoc / Fructose-bisphosphate aldolase C / P05063
  
Possible biological names infered from orthology : aldolase, fructose-bisphosphate C / P09972
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B5
Gene start: 78322968
Gene end: 78327781
  
Corresponding Affymetrix probe sets: 10379153 (MoGene1.0st)   1424714_at (Mouse Genome 430 2.0 Array)   1451461_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000017534
Ensembl peptide - ENSMUSP00000099536
NCBI entrez gene - 11676     See in Manteia.
MGI - MGI:101863
RefSeq - NM_001303423
RefSeq - NM_009657
RefSeq Peptide - NP_001290352
RefSeq Peptide - NP_033787
swissprot - P05063
Ensembl - ENSMUSG00000017390
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aldocaENSDARG00000057661Danio rerio
 ALDOCENSGALG00000026077Gallus gallus
 ALDOCENSG00000109107Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Aldoa / P05064 / Fructose-bisphosphate aldolase A / P04075* / aldolase, fructose-bisphosphate A*ENSMUSG0000003069582
Aldoart1 / aldolase 1 A, retrogene 1 / ALDOA* / P04075* / aldolase, fructose-bisphosphate A*ENSMUSG0000005934380
Aldoart2 / aldolase 1 A, retrogene 2 / ALDOA* / P04075* / aldolase, fructose-bisphosphate A*ENSMUSG0000006312980
Aldob / Q91Y97 / Fructose-bisphosphate aldolase B / P05062* / aldolase, fructose-bisphosphate B*ENSMUSG0000002830771


Protein motifs (from Interpro)
Interpro ID Name
 IPR000741  Fructose-bisphosphate aldolase, class-I
 IPR013785  Aldolase-type TIM barrel
 IPR029768  Fructose-bisphosphate aldolase class-I active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006096 glycolytic process IEA
 biological_processGO:0030388 fructose 1,6-bisphosphate metabolic process ISO
 biological_processGO:0030855 epithelial cell differentiation IEA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004332 fructose-bisphosphate aldolase activity ISO
 molecular_functionGO:0008092 cytoskeletal protein binding ISO
 molecular_functionGO:0016829 lyase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Glycolysis
Gluconeogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: A830005F24Riktm1.1(KOMP)Mbp/A830005F24Rik+
Genetic Background: C57BL/6N-A830005F24Riktm1.1(KOMP)Mbp/Ucd

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gcgrtm1Mjch/Gcgrtm1Mjch,Leprtm1Jke/Leprtm1Jke
Genetic Background: involves: 129 * 129X1/SvJ * C57BL/6J * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000017390 Aldoc / P05063 / Fructose-bisphosphate aldolase C / P09972* / aldolase, fructose-bisphosphate C*  / complex






 

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