ENSMUSG00000018126


Mus musculus

Features
Gene ID: ENSMUSG00000018126
  
Biological name :Baiap2l2
  
Synonyms : Baiap2l2 / Brain-specific angiosis inhibitor 1-associated protein 2-like protein 2 / Q80Y61
  
Possible biological names infered from orthology : BAI1 associated protein 2 like 2 / Q6UXY1
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E1
Gene start: 79258195
Gene end: 79285537
  
Corresponding Affymetrix probe sets: 10430474 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000125946
Ensembl peptide - ENSMUSP00000127816
NCBI entrez gene - 207495     See in Manteia.
MGI - MGI:2652819
RefSeq - XM_006520679
RefSeq - NM_177580
RefSeq Peptide - NP_808248
swissprot - Q80Y61
Ensembl - ENSMUSG00000018126
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 baiap2l2aENSDARG00000016483Danio rerio
 baiap2l2bENSDARG00000060933Danio rerio
 BAIAP2L2ENSGALG00000012285Gallus gallus
 Q6UXY1ENSG00000128298Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9DBJ3 / Baiap2l1 / Brain-specific angiosis inhibitor 1-associated protein 2-like protein 1 / Q9UHR4* / BAI1 associated protein 2 like 1*ENSMUSG0000003885929
Baiap2 / Q8BKX1 / Brain-specific angiosis inhibitor 1-associated protein 2 / Q9UQB8* / BAI1 associated protein 2*ENSMUSG0000002537227


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR013606  IMD/I-BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR027681  I-BAR domain containing protein IRSp53/IRTKS/Pinkbar
 IPR030126  I-BAR domain containing protein Pinkbar
 IPR035593  Pinkbar, SH3
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007009 plasma membrane organization IEA
 biological_processGO:0008286 insulin receptor signaling pathway IBA
 biological_processGO:0030838 positive regulation of actin filament polymerization IBA
 biological_processGO:0051017 actin filament bundle assembly IBA
 biological_processGO:0051764 actin crosslink formation IBA
 biological_processGO:0061024 membrane organization IDA
 biological_processGO:2000251 positive regulation of actin cytoskeleton reorganization IBA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0012506 vesicle membrane ISS
 cellular_componentGO:0015629 actin cytoskeleton IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0044291 cell-cell contact zone ISS
 cellular_componentGO:0071439 clathrin complex ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005543 phospholipid binding IDA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
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Allelic Composition: Atp6v1dtm1b(EUCOMM)Hmgu/Atp6v1dtm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Atp6v1dtm1b(EUCOMM)Hmgu/Tcp

Allelic Composition: Baiap2l2tm1b(EUCOMM)Hmgu/Baiap2l2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Baiap2l2tm1b(EUCOMM)Hmgu/Ics

 MP:0006359 absent startle reflex "failure to respond to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Baiap2l2tm1b(EUCOMM)Hmgu/Baiap2l2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Baiap2l2tm1b(EUCOMM)Hmgu/Ics

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
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Allelic Composition: Atp6v1dtm1b(EUCOMM)Hmgu/Atp6v1dtm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Atp6v1dtm1b(EUCOMM)Hmgu/Tcp

 MP:0011960 abnormal eye anterior chamber depth "anomaly in the distance between the iris and the cornea at the center plane (maximum distance) of the anterior chamber, compared to controls" [MGI:csmith]
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Allelic Composition: Baiap2l2tm1b(EUCOMM)Hmgu/Baiap2l2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Baiap2l2tm1b(EUCOMM)Hmgu/Ics

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Atp6v1dtm1b(EUCOMM)Hmgu/Atp6v1dtm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Atp6v1dtm1b(EUCOMM)Hmgu/Tcp

Allelic Composition: Baiap2l2tm1b(EUCOMM)Hmgu/Baiap2l2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Baiap2l2tm1b(EUCOMM)Hmgu/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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