ENSMUSG00000038859


Mus musculus

Features
Gene ID: ENSMUSG00000038859
  
Biological name :Baiap2l1
  
Synonyms : Baiap2l1 / Brain-specific angiosis inhibitor 1-associated protein 2-like protein 1 / Q9DBJ3
  
Possible biological names infered from orthology : BAI1 associated protein 2 like 1 / Q9UHR4
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G2
Gene start: 144264526
Gene end: 144358112
  
Corresponding Affymetrix probe sets: 10535559 (MoGene1.0st)   1424951_at (Mouse Genome 430 2.0 Array)   1451539_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000053129
NCBI entrez gene - 66898     See in Manteia.
MGI - MGI:1914148
RefSeq - NM_025833
RefSeq Peptide - NP_080109
swissprot - Q9DBJ3
Ensembl - ENSMUSG00000038859
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 baiap2l1aENSDARG00000029305Danio rerio
 baiap2l1bENSDARG00000031119Danio rerio
 BAIAP2L1ENSGALG00000003548Gallus gallus
 Q9UHR4ENSG00000006453Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Baiap2 / Q8BKX1 / Brain-specific angiosis inhibitor 1-associated protein 2 / Q9UQB8* / BAI1 associated protein 2*ENSMUSG0000002537239
Q80Y61 / Baiap2l2 / Brain-specific angiosis inhibitor 1-associated protein 2-like protein 2 / Q6UXY1* / BAI1 associated protein 2 like 2*ENSMUSG0000001812630


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR013606  IMD/I-BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR027681  I-BAR domain containing protein IRSp53/IRTKS/Pinkbar
 IPR030060  I-BAR domain containing protein IRTKS
 IPR035592  IRTKS, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007009 plasma membrane organization IEA
 biological_processGO:0008286 insulin receptor signaling pathway IBA
 biological_processGO:0009617 response to bacterium IEA
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0046626 regulation of insulin receptor signaling pathway IEA
 biological_processGO:0051017 actin filament bundle assembly IBA
 biological_processGO:0051764 actin crosslink formation IBA
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:2000251 positive regulation of actin cytoskeleton reorganization IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0070064 proline-rich region binding IEA
 molecular_functionGO:0098641 cadherin binding involved in cell-cell adhesion IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Irf7tm1Ttg/Irf7tm1Ttg
Genetic Background: B6.129P2-Irf7tm1Ttg

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Irf7tm1Ttg/Irf7tm1Ttg
Genetic Background: B6.129P2-Irf7tm1Ttg

 MP:0005331 insulin resistance "diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Irf7tm1Ttg/Irf7tm1Ttg
Genetic Background: B6.129P2-Irf7tm1Ttg

 MP:0013279 increased fasted circulating glucose level "increase in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
Show

Allelic Composition: Irf7tm1Ttg/Irf7tm1Ttg
Genetic Background: B6.129P2-Irf7tm1Ttg

 MP:0020102 increased hepatic glucose production "increased production of glucose in the liver" [GOC:NV]
Show

Allelic Composition: Irf7tm1Ttg/Irf7tm1Ttg
Genetic Background: B6.129P2-Irf7tm1Ttg

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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