ENSMUSG00000018659


Mus musculus

Features
Gene ID: ENSMUSG00000018659
  
Biological name :Pnpo
  
Synonyms : Pnpo / Pyridoxine-5-phosphate oxidase / Q91XF0
  
Possible biological names infered from orthology : pyridoxamine 5-phosphate oxidase / Q9NVS9
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 96937825
Gene end: 96943986
  
Corresponding Affymetrix probe sets: 10390299 (MoGene1.0st)   1415793_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000103255
Ensembl peptide - ENSMUSP00000018803
NCBI entrez gene - 103711     See in Manteia.
MGI - MGI:2144151
RefSeq - NM_134021
RefSeq Peptide - NP_598782
swissprot - A2A6E7
swissprot - Q91XF0
Ensembl - ENSMUSG00000018659
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pnpoENSDARG00000017612Danio rerio
 PNPOENSGALG00000036683Gallus gallus
 PNPOENSG00000108439Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000659  Pyridoxamine 5"-phosphate oxidase
 IPR011576  Pyridoxamine 5"-phosphate oxidase, putative
 IPR012349  FMN-binding split barrel
 IPR019576  Pyridoxine 5"-phosphate oxidase, dimerisation, C-terminal
 IPR019740  Pyridoxamine 5"-phosphate oxidase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008615 pyridoxine biosynthetic process IEA
 biological_processGO:0042823 pyridoxal phosphate biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004733 pyridoxamine-phosphate oxidase activity IEA
 molecular_functionGO:0010181 FMN binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0048037 cofactor binding IEA


Pathways (from Reactome)
Pathway description
Vitamins B6 activation to pyridoxal phosphate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000018659 Pnpo / Q91XF0 / Pyridoxine-5-phosphate oxidase / Q9NVS9* / pyridoxamine 5-phosphate oxidase*  / complex






 

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contact: otassy@igbmc.fr