ENSMUSG00000018845


Mus musculus

Features
Gene ID: ENSMUSG00000018845
  
Biological name :Unc45b
  
Synonyms : Q8CGY6 / Unc45b / unc-45 myosin chaperone B
  
Possible biological names infered from orthology : Q8IWX7
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: C
Gene start: 82910550
Gene end: 82943403
  
Corresponding Affymetrix probe sets: 10379594 (MoGene1.0st)   1436939_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000018989
Ensembl peptide - ENSMUSP00000103795
Ensembl peptide - ENSMUSP00000129405
NCBI entrez gene - 217012     See in Manteia.
MGI - MGI:2443377
RefSeq - NM_178680
RefSeq Peptide - NP_848795
swissprot - Q8CGY6
Ensembl - ENSMUSG00000018845
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DGE9ENSDARG00000008433Danio rerio
 UNC45BENSGALG00000002186Gallus gallus
 Q8IWX7ENSG00000141161Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q99KD5 / Unc45a / unc-45 myosin chaperone A / Q9H3U1*ENSMUSG0000003053355
Rpap3 / Q9D706 / RNA polymerase II-associated protein 3 / Q9H6T3*ENSMUSG0000002246611
Spag1 / Q80ZX8 / Sperm-associated antigen 1 / Q07617*ENSMUSG0000003761710
Q9CZW5 / Tomm70a / Mitochondrial import receptor subunit TOM70 / O94826* / TOMM70* / translocase of outer mitochondrial membrane 70*ENSMUSG000000227529
Q9CYG7 / Tomm34 / Mitochondrial import receptor subunit TOM34 / Q15785* / translocase of outer mitochondrial membrane 34*ENSMUSG000000183227
Ttc1 / Q91Z38 / tetratricopeptide repeat domain 1 / Q99614*ENSMUSG000000412786


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR011989  Armadillo-like helical
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR016024  Armadillo-type fold
 IPR019734  Tetratricopeptide repeat
 IPR024660  UNC-45/Cro1/She4, central domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002088 lens development in camera-type eye ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0061077 chaperone-mediated protein folding IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0051879 Hsp90 protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011095 complete embryonic lethality between implantation and placentation "death of all organisms of a given genotype in a population between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith]
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Allelic Composition: Hsp90aa1Tg(Tyr)2396BOve/Hsp90aa1Tg(Tyr)2396BOve
Genetic Background: FVB/N-Hsp90aa1Tg(Tyr)2396BOve

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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