ENSMUSG00000018974


Mus musculus

Features
Gene ID: ENSMUSG00000018974
  
Biological name :Sart3
  
Synonyms : Mus musculus squamous cell carcinoma antigen recognized by T cells 3 (Sart3), transcript variant 3, mRNA. / Q9JLI8 / Sart3
  
Possible biological names infered from orthology : Q15020 / squamous cell carcinoma antigen recognized by T cells 3
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 113742446
Gene end: 113772510
  
Corresponding Affymetrix probe sets: 10532720 (MoGene1.0st)   1417547_at (Mouse Genome 430 2.0 Array)   1417548_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019118
Ensembl peptide - ENSMUSP00000143778
NCBI entrez gene - 53890     See in Manteia.
MGI - MGI:1858230
RefSeq - XM_017320991
RefSeq - NM_001356623
RefSeq - NM_016926
RefSeq - XM_006530405
RefSeq - XM_006530406
RefSeq Peptide - NP_001343552
RefSeq Peptide - NP_058622
swissprot - Q9JLI8
Ensembl - ENSMUSG00000018974
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sart3ENSDARG00000008032Danio rerio
 SART3ENSGALG00000039472Gallus gallus
 SART3ENSG00000075856Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR003107  HAT (Half-A-TPR) repeat
 IPR008669  LSM-interacting domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR034217  SART3, RNA recognition motif 1
 IPR034218  SART3, RNA recognition motif 2
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000244 spliceosomal tri-snRNP complex assembly ISS
 biological_processGO:0000387 spliceosomal snRNP assembly ISO
 biological_processGO:0000398 mRNA splicing, via spliceosome ISO
 biological_processGO:0000902 cell morphogenesis IMP
 biological_processGO:0006334 nucleosome assembly ISS
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010468 regulation of gene expression ISO
 biological_processGO:0048872 homeostasis of number of cells IMP
 biological_processGO:0071425 hematopoietic stem cell proliferation IMP
 biological_processGO:1903586 positive regulation of histone deubiquitination ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005691 U6atac snRNP ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0071001 U4/U6 snRNP ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017070 U6 snRNA binding ISS
 molecular_functionGO:0030621 U4 snRNA binding IEA
 molecular_functionGO:0030624 U6atac snRNA binding ISO
 molecular_functionGO:0042393 histone binding ISS
 molecular_functionGO:1990381 ubiquitin-specific protease binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002123 abnormal hematopoiesis "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Kltm1Lex/Kltm1Lex
Genetic Background: B6.129S-Kltm1Lex

 MP:0004810 decreased hematopoietic stem cell number "reduced cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kltm1Lex/Kltm1Lex
Genetic Background: B6.129S-Kltm1Lex

 MP:0006410 abnormal common myeloid progenitor cell morphology "anomaly in the structure of the hematopoietic stem cells that are capable of forming any of the myeloid lineage cells (erythrocytes, granulocytes, thrombocytes, monocytes, and mast cells) but not cells of the lymphoid lineage" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kltm1Lex/Kltm1Lex
Genetic Background: B6.129S-Kltm1Lex

 MP:0008973 decreased erythroid progenitor cell number "reduced numbers of progenitors of the erythrocyte lineage" [CL:0000038, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kltm1Lex/Kltm1Lex
Genetic Background: B6.129S-Kltm1Lex

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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