ENSMUSG00000019088


Mus musculus

Features
Gene ID: ENSMUSG00000019088
  
Biological name :Dnase1l1
  
Synonyms : Deoxyribonuclease-1-like 1 / Dnase1l1 / Q9D7J6
  
Possible biological names infered from orthology : P49184
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A7.3
Gene start: 74273217
Gene end: 74282337
  
Corresponding Affymetrix probe sets: 10605303 (MoGene1.0st)   1429173_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019232
Ensembl peptide - ENSMUSP00000075218
Ensembl peptide - ENSMUSP00000109827
Ensembl peptide - ENSMUSP00000113515
NCBI entrez gene - 69537     See in Manteia.
MGI - MGI:109628
RefSeq - XM_017318614
RefSeq - NM_001172154
RefSeq - NM_027109
RefSeq - XM_006528272
RefSeq - XM_006528273
RefSeq - XM_017318613
RefSeq Peptide - NP_081385
RefSeq Peptide - NP_001165625
swissprot - I7HPX5
swissprot - I7HIQ0
swissprot - Q9D7J6
swissprot - A0A158SIT2
Ensembl - ENSMUSG00000019088
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnase1l1ENSDARG00000005464Danio rerio
 P49184ENSG00000013563Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O55070 / Dnase1l3 / Deoxyribonuclease gamma / Q13609* / deoxyribonuclease 1 like 3*ENSMUSG0000002527938
Q9D1G0 / Dnase1l2 / Deoxyribonuclease-1-like 2 / Q92874*ENSMUSG0000002413636
Dnase1 / P49183 / Mus musculus deoxyribonuclease I (Dnase1), transcript variant 2, mRNA. / P24855* / deoxyribonuclease 1*ENSMUSG0000000598035


Protein motifs (from Interpro)
Interpro ID Name
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR016202  Deoxyribonuclease I
 IPR018057  Deoxyribonuclease I, active site
 IPR033125  Deoxyribonuclease I, conservied site
 IPR036691  Endonuclease/exonuclease/phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006308 DNA catabolic process IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004536 deoxyribonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr2tm2Ewj/Fgfr2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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