ENSMUSG00000025279


Mus musculus

Features
Gene ID: ENSMUSG00000025279
  
Biological name :Dnase1l3
  
Synonyms : Deoxyribonuclease gamma / Dnase1l3 / O55070
  
Possible biological names infered from orthology : deoxyribonuclease 1 like 3 / Q13609
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: A1
Gene start: 7964533
Gene end: 7994573
  
Corresponding Affymetrix probe sets: 10417526 (MoGene1.0st)   1421056_at (Mouse Genome 430 2.0 Array)   1421057_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026315
NCBI entrez gene - 13421     See in Manteia.
MGI - MGI:1314633
RefSeq - NM_007870
RefSeq - XM_006517921
RefSeq Peptide - NP_031896
swissprot - O55070
Ensembl - ENSMUSG00000025279
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DNASE1L3ENSGALG00000005688Gallus gallus
 Q13609ENSG00000163687Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dnase1 / P49183 / Mus musculus deoxyribonuclease I (Dnase1), transcript variant 2, mRNA. / P24855* / deoxyribonuclease 1*ENSMUSG0000000598042
Q9D1G0 / Dnase1l2 / Deoxyribonuclease-1-like 2 / Q92874*ENSMUSG0000002413639
Q9D7J6 / Dnase1l1 / Deoxyribonuclease-1-like 1 / P49184*ENSMUSG0000001908839


Protein motifs (from Interpro)
Interpro ID Name
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR016202  Deoxyribonuclease I
 IPR018057  Deoxyribonuclease I, active site
 IPR033125  Deoxyribonuclease I, conservied site
 IPR036691  Endonuclease/exonuclease/phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000737 DNA catabolic process, endonucleolytic IDA
 biological_processGO:0002283 neutrophil activation involved in immune response IDA
 biological_processGO:0002673 regulation of acute inflammatory response IDA
 biological_processGO:0006308 DNA catabolic process IEA
 biological_processGO:0006309 apoptotic DNA fragmentation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0010623 programmed cell death involved in cell development IDA
 biological_processGO:0012501 programmed cell death IEA
 biological_processGO:0070948 regulation of neutrophil mediated cytotoxicity IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IEA
 molecular_functionGO:0004536 deoxyribonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000313 abnormal cell death "anomalous cessation of function at the cellular level" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Myo1gtm1.2Mfk/Myo1gtm1.2Mfk,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: C57BL/6 * FVB/N * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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