ENSG00000013563


Homo sapiens

Features
Gene ID: ENSG00000013563
  
Biological name :DNASE1L1
  
Synonyms : deoxyribonuclease 1 like 1 / DNASE1L1 / P49184
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q28
Gene start: 154401238
Gene end: 154412112
  
Corresponding Affymetrix probe sets: 203912_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000377255
Ensembl peptide - ENSP00000416881
Ensembl peptide - ENSP00000410281
Ensembl peptide - ENSP00000395591
Ensembl peptide - ENSP00000393346
Ensembl peptide - ENSP00000393000
Ensembl peptide - ENSP00000014935
Ensembl peptide - ENSP00000309168
Ensembl peptide - ENSP00000358822
Ensembl peptide - ENSP00000358823
Ensembl peptide - ENSP00000358824
NCBI entrez gene - 1774     See in Manteia.
OMIM - 300081
RefSeq - XM_017029332
RefSeq - XM_011531122
RefSeq - XM_005277829
RefSeq - NM_001009932
RefSeq - NM_001009933
RefSeq - NM_001009934
RefSeq - NM_006730
RefSeq - NM_001303620
RefSeq Peptide - NP_001009932
RefSeq Peptide - NP_001009933
RefSeq Peptide - NP_001009934
RefSeq Peptide - NP_001290549
RefSeq Peptide - NP_006721
swissprot - E7ESG1
swissprot - P49184
swissprot - E7EUJ0
swissprot - Q5HY40
swissprot - A3KQT1
swissprot - A6QRJ0
Ensembl - ENSG00000013563
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnase1l1ENSDARG00000005464Danio rerio
 Q9D7J6ENSMUSG00000019088Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q92874 / DNASE1L2 / deoxyribonuclease 1 like 2ENSG0000016796838
Q13609 / DNASE1L3 / deoxyribonuclease 1 like 3ENSG0000016368738
DNASE1 / P24855 / deoxyribonuclease 1ENSG0000021391835


Protein motifs (from Interpro)
Interpro ID Name
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR016202  Deoxyribonuclease I
 IPR018057  Deoxyribonuclease I, active site
 IPR033125  Deoxyribonuclease I, conservied site
 IPR036691  Endonuclease/exonuclease/phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006259 DNA metabolic process TAS
 biological_processGO:0006308 DNA catabolic process IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004536 deoxyribonuclease activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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