ENSG00000167968


Homo sapiens

Features
Gene ID: ENSG00000167968
  
Biological name :DNASE1L2
  
Synonyms : deoxyribonuclease 1 like 2 / DNASE1L2 / Q92874
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 2235816
Gene end: 2238711
  
Corresponding Affymetrix probe sets: 207192_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000455478
Ensembl peptide - ENSP00000482627
Ensembl peptide - ENSP00000316938
Ensembl peptide - ENSP00000371874
Ensembl peptide - ENSP00000454562
Ensembl peptide - ENSP00000455358
NCBI entrez gene - 1775     See in Manteia.
OMIM - 602622
RefSeq - NM_001301680
RefSeq - NM_001374
RefSeq - XM_011522399
RefSeq Peptide - NP_001288609
RefSeq Peptide - NP_001365
swissprot - Q92874
swissprot - H3BPU8
Ensembl - ENSG00000167968
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnase1ENSDARG00000012539Danio rerio
 ENSGALG00000046313Gallus gallus
 DNASE1ENSGALG00000041066Gallus gallus
 Q9D1G0ENSMUSG00000024136Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNASE1 / P24855 / deoxyribonuclease 1ENSG0000021391851
Q13609 / DNASE1L3 / deoxyribonuclease 1 like 3ENSG0000016368742
P49184 / DNASE1L1 / deoxyribonuclease 1 like 1ENSG0000001356338


Protein motifs (from Interpro)
Interpro ID Name
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR016202  Deoxyribonuclease I
 IPR018057  Deoxyribonuclease I, active site
 IPR033125  Deoxyribonuclease I, conservied site
 IPR036691  Endonuclease/exonuclease/phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001942 hair follicle development IEA
 biological_processGO:0003335 corneocyte development IEA
 biological_processGO:0006259 DNA metabolic process TAS
 biological_processGO:0006308 DNA catabolic process IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004536 deoxyribonuclease activity TAS
 molecular_functionGO:0005509 calcium ion binding TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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