ENSMUSG00000020175


Mus musculus

Features
Gene ID: ENSMUSG00000020175
  
Biological name :Rab36
  
Synonyms : Mus musculus RAB36, member RAS onco family (Rab36), transcript variant 1, mRNA. / Q8CAM5 / Rab36
  
Possible biological names infered from orthology : O95755 / RAB36, member RAS oncogene family
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 75037058
Gene end: 75054748
  
Corresponding Affymetrix probe sets: 10363970 (MoGene1.0st)   1431136_at (Mouse Genome 430 2.0 Array)   1436471_at (Mouse Genome 430 2.0 Array)   1455064_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121693
Ensembl peptide - ENSMUSP00000020391
Ensembl peptide - ENSMUSP00000118718
Ensembl peptide - ENSMUSP00000119399
NCBI entrez gene - 76877     See in Manteia.
MGI - MGI:1924127
RefSeq - XM_011243599
RefSeq - XM_006514288
RefSeq - XM_006514289
RefSeq - XM_006514290
RefSeq - XM_006514291
RefSeq - XM_006514292
RefSeq - XM_006514293
RefSeq - XM_006514294
RefSeq - NM_001359270
RefSeq - NM_001359271
RefSeq - NM_029781
RefSeq - XM_006514286
RefSeq - XM_006514287
RefSeq Peptide - NP_001346199
RefSeq Peptide - NP_001346200
RefSeq Peptide - NP_001346201
RefSeq Peptide - NP_084057
swissprot - A0A1X7SB53
swissprot - Q8CAM5
swissprot - D3YZ27
Ensembl - ENSMUSG00000020175
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab36ENSDARG00000014058Danio rerio
 RAB36ENSGALG00000006710Gallus gallus
 RAB36ENSG00000100228Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rab34 / RAB34, member RAS oncogene family / P0DI83* / Q9BZG1*ENSMUSG0000000205951
Rab6a / P35279 / RAB6A, member RAS oncogene family / RAB6C* / RAB6D* / Q9H0N0* / P20340* / RAB6C, member RAS oncogene family* / RAB6D, member RAS oncogene family*ENSMUSG0000003070428
Rab6b / P61294 / RAB6B, member RAS oncogene family / Q9NRW1*ENSMUSG0000003254928


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic
RAB geranylgeranylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000432 abnormal head morphology "anomalous structure or development of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0005179 decreased total circulating cholesterol level "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0005564 increased hemoglobin content "increase in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
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Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

 MP:0005641 increased mean corpuscular hemoglobin concentration "greater than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936]
Show

Allelic Composition: Psen1tm1.1(KOMP)Vlcg/Psen1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psen1tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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