ENSMUSG00000032549


Mus musculus

Features
Gene ID: ENSMUSG00000032549
  
Biological name :Rab6b
  
Synonyms : P61294 / Rab6b / RAB6B, member RAS oncogene family
  
Possible biological names infered from orthology : Q9NRW1
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F1
Gene start: 103111787
Gene end: 103185276
  
Corresponding Affymetrix probe sets: 10588283 (MoGene1.0st)   1434914_at (Mouse Genome 430 2.0 Array)   1437107_at (Mouse Genome 430 2.0 Array)   1455924_at (Mouse Genome 430 2.0 Array)   1460617_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035155
Ensembl peptide - ENSMUSP00000149595
NCBI entrez gene - 270192     See in Manteia.
MGI - MGI:107283
RefSeq - XM_006511737
RefSeq - NM_173781
RefSeq - XM_006511736
RefSeq Peptide - NP_776142
swissprot - P61294
swissprot - Q0PD53
swissprot - A0A1L1SRS6
Ensembl - ENSMUSG00000032549
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab6baENSDARG00000034522Danio rerio
 rab6bbENSDARG00000031343Danio rerio
 RAB6BENSGALG00000026278Gallus gallus
 RAB6BENSG00000154917Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rab6a / P35279 / RAB6A, member RAS oncogene family / RAB6C* / RAB6D* / Q9H0N0* / P20340* / RAB6C, member RAS oncogene family* / RAB6D, member RAS oncogene family*ENSMUSG0000003070491
Rab36 / Q8CAM5 / Mus musculus RAB36, member RAS onco family (Rab36), transcript variant 1, mRNA. / O95755* / RAB36, member RAS oncogene family*ENSMUSG0000002017536
Rab34 / RAB34, member RAS oncogene family / P0DI83* / Q9BZG1*ENSMUSG0000000205933


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IBA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IBA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0031489 myosin V binding IEA


Pathways (from Reactome)
Pathway description
COPI-independent Golgi-to-ER retrograde traffic
Retrograde transport at the Trans-Golgi-Network
TBC/RABGAPs
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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