ENSG00000154917


Homo sapiens

Features
Gene ID: ENSG00000154917
  
Biological name :RAB6B
  
Synonyms : Q9NRW1 / RAB6B / RAB6B, member RAS oncogene family
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q22.1
Gene start: 133824239
Gene end: 133895836
  
Corresponding Affymetrix probe sets: 210127_at (Human Genome U133 Plus 2.0 Array)   221792_at (Human Genome U133 Plus 2.0 Array)   225259_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418540
Ensembl peptide - ENSP00000437797
Ensembl peptide - ENSP00000419941
Ensembl peptide - ENSP00000419526
Ensembl peptide - ENSP00000419381
Ensembl peptide - ENSP00000285208
Ensembl peptide - ENSP00000417433
NCBI entrez gene - 51560     See in Manteia.
OMIM - 615852
RefSeq - NM_016577
RefSeq - XM_011512893
RefSeq Peptide - NP_057661
swissprot - Q9NRW1
swissprot - J3KR73
swissprot - C9JB90
swissprot - C9J0I2
swissprot - C9JU14
Ensembl - ENSG00000154917
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab6baENSDARG00000034522Danio rerio
 rab6bbENSDARG00000031343Danio rerio
 RAB6BENSGALG00000026278Gallus gallus
 Rab6bENSMUSG00000032549Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB6A / P20340 / RAB6A, member RAS oncogene familyENSG0000017558289
RAB6D / RAB6D, member RAS oncogene familyENSG0000023308783
RAB6C / Q9H0N0 / RAB6C, member RAS oncogene familyENSG0000022201482
RAB41 / Q5JT25 / RAB41, member RAS oncogene familyENSG0000014712765
RAB36 / O95755 / RAB36, member RAS oncogene familyENSG0000010022834
RAB34 / P0DI83 / Q9BZG1 / RAB34, member RAS oncogene familyENSG0000010911327


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IBA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IBA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0031489 myosin V binding IPI


Pathways (from Reactome)
Pathway description
COPI-independent Golgi-to-ER retrograde traffic
Retrograde transport at the Trans-Golgi-Network
TBC/RABGAPs
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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