MP:0000259 | abnormal vascular development | "malformation or aberrant differentiation of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17509] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0000786 | abnormal neuroepithelial layer differentiation | "malformation or arrest of differentiation or patterning of the epithelial layer of the brain" [J:45302] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0000928 | incomplete cephalic closure | "arrest of the fusion of the cephalic neural folds" [J:12622] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0001126 | abnormal ovary morphology | "malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Tg(Adipoq-cre)1Evdr/0 Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6J * FVB/NJ
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MP:0001130 | abnormal ovarian folliculogenesis | "atypical formation or failure to form the spherical ovum in the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:35782] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001131 | abnormal ovarian follicles | "malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042] |
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Allelic Composition: Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Tg(Adipoq-cre)1Evdr/0 Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6J * FVB/NJ
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MP:0001577 | anemia | "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0001689 | incomplete somite formation | "arrest of differentiation or patterning of the somites" [J:62882] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
Allelic Composition: Mgat1tm1Pst/Mgat1tm1Pst Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1 * SJL
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MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
Allelic Composition: Mgat1tm1Pst/Mgat1tm1Pst Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1 * SJL
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MP:0001701 | incomplete embryo turning | "arrest of the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [J:62571] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0001706 | abnormal left-right axis patterning | "anomaly in the formation or development of the body or a specific organ of the body in relation to the left and right sides of the body or organ" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0001730 | embryonic growth arrest | "the cessation of development beyond a particular stage" [J:17509] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0001750 | increased circulating follicle stimulating hormone level | "higher than normal levels in the blood stream of FSH, the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [J:35782, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
Allelic Composition: Mgat1tm1Pst/Mgat1tm1Pst Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1 * SJL
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MP:0001923 | reduced female fertility | "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: F2rtm1Ajc/F2rtm1Ajc Genetic Background: involves: 129S4/SvJae * C57BL/6J
Allelic Composition: Mgat1tm2Jxm/Mgat1tm1Pst,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/? Genetic Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6
Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Tg(Adipoq-cre)1Evdr/0 Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6J * FVB/NJ
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MP:0001931 | abnormal oogenesis | "atypical formation or failure to form the female germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: F2rtm1Ajc/F2rtm1Ajc Genetic Background: involves: 129S4/SvJae * C57BL/6J
Allelic Composition: Mgat1tm2Jxm/Mgat1tm1Pst,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129/Sv * C57BL/6 * SJL
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MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: F2rtm1Ajc/F2rtm1Ajc Genetic Background: involves: 129S4/SvJae * C57BL/6J
Allelic Composition: Mgat1tm2Jxm/Mgat1tm1Pst,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/? Genetic Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6
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MP:0002151 | abnormal neural tube morphology/development | "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0002679 | abnormal corpora lutea | "malformed or absent yellow endocrine body formed in the ovary after follicle rupture" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0002682 | reduced number of mature ovarian follicles | "fewer than normal numbers of spehroidal cell aggregations in the ovary containing the ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/? Genetic Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6
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MP:0002766 | situs inversus | "lateral transposition of the viscera of the thorax and abdomen, sometimes incomplete" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0002780 | decreased circulating testosterone level | "less than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0002783 | abnormal ovarian secretion | "malfunction of the production and/or release of hormones from ovarian tissue" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0003355 | reduced ovulation | "reduction in the frequency in which an ovum is released from a rupturing ovarian follicle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0003696 | abnormal zona pellucida | "anomaly or absence of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: F2rtm1Ajc/F2rtm1Ajc Genetic Background: involves: 129S4/SvJae * C57BL/6J
Allelic Composition: Mgat1tm2Jxm/Mgat1tm1Pst,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0003717 | pallor | "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Mgat1tm1Pst/Mgat1tm1Pst Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1 * SJL
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MP:0003953 | abnormal hormone level | "aberrant tissue or circulating concentration of any substance, usually a peptide or steroid, that has a specific metabolic regulatory effect on the activity or behavior of cells expressing a receptor for the hormone" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0003984 | embryonic growth retardation | "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mgat1tm1Pst/Mgat1tm1Pst Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1 * SJL
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MP:0004252 | abnormal direction of looping morphogenesis | "deviation from the normal rightward direction of cardiac looping" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0004856 | decreased ovary weight | "reduction in the average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0005431 | oocyte depletion | "reduced numbers or absence of germ cells in the female" [llw2:Linda Washburn , Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/? Genetic Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6
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MP:0006055 | abnormal vascular endothelial cell morphology | "malformation in the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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MP:0008868 | abnormal granulosa cell morphology | "any structural anomaly of a supporting cell for the developing female gamete in the ovary of mammals; granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle" [MESH:A.05.360.319.114.630.535.200] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0008871 | abnormal ovarian follicle number | "abnormal numbers of spheroid cell aggregations in the ovary" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0008995 | early reproductive senescence | "loss of reproductive capacity occurring at an earlier than expected age" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0009363 | abnormal secondary ovarian follicle morphology | "any structural abnormality in the ovarian follicle in which the primary oocyte attains its full size and is surrounded by an extracellular glycoprotein layer (zona pellucida) that separates it from a peripheral layer of follicular cells permeated by one or more fluid-filled antra; the primary oocyte occupies the cumulus oophorus while the theca of the follicle develops into internal and external layers" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0009375 | thin zona pellucida | "reduced thickness of the solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: F2rtm1Ajc/F2rtm1Ajc Genetic Background: involves: 129S4/SvJae * C57BL/6J
Allelic Composition: Mgat1tm2Jxm/Mgat1tm1Pst,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129/Sv * C57BL/6 * SJL
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MP:0009433 | polyovular ovarian follicle | "an ovarian follicle containing more than one oocyte (ovum)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
Allelic Composition: Mgat1tm1Pst/Mgat1tm1Pst Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1 * SJL
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MP:0011124 | increased primary ovarian follicle number | "greater than normal numbers of the ovarian follicle prior to the appearance of an antrum, normally marked by developmental changes in the primary oocyte and follicular cells so that the latter form one or more layers of cuboidal or columnar cells; the follicle becomes surrounded by a sheath of stroma, the theca" [MGI:csmith] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0011129 | decreased secondary ovarian follicle number | "fewer than normal numbers of the ovarian follicle in which the primary oocyte attains its full size and is surrounded by an extracellular glycoprotein layer (zona pellucida) that separates it from a peripheral layer of follicular cells permeated by one or more fluid-filled antra; the primary oocyte occupies the cumulus oophorus while the theca of the follicle develops into internal and external layers" [MGI:csmith] |
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Allelic Composition: C1galt1tm1.1Rpmc/C1galt1tm1.1Rpmc,Mgat1tm2Jxm/Mgat1tm2Jxm,Tg(Zp3-cre)1Gwh/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0012707 | incomplete caudal neuropore closure | "incomplete joining together of the neural folds of the caudal opening of the neural tube; failure of caudal neuropore closure results in spina bifida, the severity of which depends on how much of the spinal cord remains exposed" [MGI:anna] |
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Allelic Composition: Mgat1tm1Pst/Mgat1tm1Pst Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1 * SJL
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MP:0013176 | abnormal tail position or orientation | " tail is displaced from the normal location and/or does not orient in a typical pattern" [MGI:anna] |
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Allelic Composition: Lim2To3/Lim2+ Genetic Background: involves: 102 * C3H/He * T STOCK
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