ENSMUSG00000020585


Mus musculus

Features
Gene ID: ENSMUSG00000020585
  
Biological name :Laptm4a
  
Synonyms : Laptm4a / lysosomal-associated protein transmembrane 4A
  
Possible biological names infered from orthology : lysosomal protein transmembrane 4 alpha / Q15012
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: A1.1
Gene start: 8921664
Gene end: 8938742
  
Corresponding Affymetrix probe sets: 10394477 (MoGene1.0st)   1423368_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020909
NCBI entrez gene - 17775     See in Manteia.
MGI - MGI:108017
RefSeq - NM_008640
RefSeq Peptide - NP_032666
swissprot - E9QLR3
Ensembl - ENSMUSG00000020585
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 laptm4aENSDARG00000006397Danio rerio
 LAPTM4AENSGALG00000016479Gallus gallus
 Q15012ENSG00000068697Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q91XQ6 / Laptm4b / Lysosomal-associated transmembrane protein 4B / Q86VI4* / lysosomal protein transmembrane 4 beta*ENSMUSG0000002225732


Protein motifs (from Interpro)
Interpro ID Name
 IPR004687  Lysosomal-associated transmembrane protein 4/5
 IPR018396  Lysosomal-associated transmembrane protein, 4A/5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003233 prolonged QT interval "increase in the length of time required for ventricular depolarization and repolarization to occur, usually as a result of increased repolarization time" [J:93197, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H

 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H

 MP:0010570 prolonged ST segment "increase in the length of time between the end of S-wave and the beginning of T-wave; reflects the amount of time the ventricles remain electrically depolarized" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H

 MP:0011965 decreased total retina thickness "decreased width of the retina through the center plane" [MGI:csmith]
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Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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