ENSMUSG00000020844


Mus musculus

Features
Gene ID: ENSMUSG00000020844
  
Biological name :Nxn
  
Synonyms : Nucleoredoxin / Nxn / P97346
  
Possible biological names infered from orthology : Q6DKJ4
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B5
Gene start: 76257198
Gene end: 76399140
  
Corresponding Affymetrix probe sets: 10388532 (MoGene1.0st)   1422465_a_at (Mouse Genome 430 2.0 Array)   1422466_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021204
NCBI entrez gene - 18230     See in Manteia.
MGI - MGI:109331
RefSeq - NM_008750
RefSeq Peptide - NP_032776
swissprot - P97346
Ensembl - ENSMUSG00000020844
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nxnENSDARG00000033978Danio rerio
 NXNENSGALG00000004793Gallus gallus
 NXNENSG00000167693Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nxnl1 / Q8VC33 / Nucleoredoxin-like protein 1 / Q96CM4* / nucleoredoxin like 1*ENSMUSG0000003482911
Nxnl2 / Q9D531 / Nucleoredoxin-like protein 2 / Q5VZ03* / nucleoredoxin like 2*ENSMUSG0000002139610


Protein motifs (from Interpro)
Interpro ID Name
 IPR012336  Thioredoxin-like fold
 IPR013766  Thioredoxin domain
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IMP
 biological_processGO:0031397 negative regulation of protein ubiquitination IMP
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0072358 cardiovascular system development IMP
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004791 thioredoxin-disulfide reductase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0047134 protein-disulfide reductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Bay

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

 MP:0000150 abnormal rib morphology "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]
Show

Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0000157 abnormal sternum morphology "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]
Show

Allelic Composition: Nox4tm1.1Hwsc/Nox4tm1.1Hwsc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000284 double outlet right ventricle "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

 MP:0000428 abnormal craniofacial morphology "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0000438 abnormal skull morphology "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0000443 abnormal snout morphology "anomalous structure or development of the anterior facial part of the muzzle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0000602 enlarged sinusoidal spaces "larger than normal sized cavities in the liver " [J:23170]
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Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

 MP:0001293 anophthalmia "congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979]
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Allelic Composition: Nxnem1(IMPC)J/Nxnem1(IMPC)J
Genetic Background: C57BL/6NJ-Nxnem1(IMPC)J/J

 MP:0001340 abnormal eyelid morphology "malformation of the skin folds covering the front of the eyeball" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
Show

Allelic Composition: Nxnem1(IMPC)J/Nxnem1(IMPC)J
Genetic Background: C57BL/6NJ-Nxnem1(IMPC)J/J

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Bay

 MP:0002546 mydriasis "dilation of one or both pupils" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0002633 persistent truncus arteriosis "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nox4tm1.1Hwsc/Nox4tm1.1Hwsc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0002768 small adrenal glands "reduced size of endocrine glands located above the kidneys responsible for hormone and epinephrine secretion" [J:78062]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0003047 abnormal thoracic vertebrae morphology "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0003743 abnormal facial morphology "anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Bay

 MP:0003826 abnormal Mullerian duct morphology "malformation of the transient embryonic tubes that empty into the cloaca and in the female develop into the oviducts, uterus, and vagina" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0004200 reduced fetal size "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nox4tm1.1Hwsc/Nox4tm1.1Hwsc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004377 small frontal bone "reduced size of the bone forming the forehead and roof of the eye orbit" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Nox4tm1.1Hwsc/Nox4tm1.1Hwsc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004647 decreased lumbar vertebrae number "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0004666 absent stapedial artery "absence of the small artery that passes through the ring of the stapes" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

 MP:0004678 split xiphoid process "the appearance of an abnormal division of the posterior tip of the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nox4tm1.1Hwsc/Nox4tm1.1Hwsc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004953 decreased spleen weight "reduction in the average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0004988 increased osteoblast cell number "greater than average number of the bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nox4tm1.1Hwsc/Nox4tm1.1Hwsc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005382 craniofacial phenotype 
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nox4tm1.1Hwsc/Nox4tm1.1Hwsc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008346 increased gamma-delta T cell number "greater number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]
Show

Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0008797 facial cleft "a cleft resulting from incomplete merging or fusion of any of the embryonic facial processes that normally unite to form the face" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Bay

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Myoz1tm1a(EUCOMM)Hmgu/Myoz1tm1a(EUCOMM)Hmgu
Genetic Background: Not Specified

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0010402 ventricular septal defect "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]
Show

Allelic Composition: Nox4tm1.1Hwsc/Nox4tm1.1Hwsc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010412 atrioventricular septal defect "defects in the thin membranous structure between the right atrium and left ventricle that arise from faulty development of the embryonic endocardial cushions; the spectrum ranges from a primum atrial septal defect and cleft mitral valve, known as a partial atrioventricular septal defect (partial AVSD), to defects of both the primum atrial septum and inlet ventricular septum and the presence of a common atrioventricular valve, referred to as complete atrioventricular septal defect (complete AVSD)" [http://emedicine.medscape.com]
Show

Allelic Composition: Nox4tm1.1Hwsc/Nox4tm1.1Hwsc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010418 perimembraneous ventricular septal defect "abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

 MP:0010912 herniated liver "protrusion of any portion of the liver from its normal anatomical position" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Egfrtm2(EGFR)Wag/Egfrtm2(EGFR)Wag
Genetic Background: 129/Sv

Allelic Composition: Nxntm1Hmik/Nxntm1Hmik
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Ucd

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Bay

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Ieg

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Ics

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Nju

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Rbrc

Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

Allelic Composition: Nxnem1(IMPC)J/Nxnem1(IMPC)J
Genetic Background: C57BL/6NJ-Nxnem1(IMPC)J/J

Allelic Composition: Nxntm1a(EUCOMM)Wtsi/Nxntm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1a(EUCOMM)Wtsi/Bay

 MP:0011495 abnormal head shape "any anomaly in the characteristic surface outline or contour of a head of an organism" [MGI:csmith]
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Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Bay

 MP:0011496 abnormal head size "anomaly in the average size of the portion of the body containing the brain and organs of sight, hearing, taste, and smell" [MGI:csmith]
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Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Bay

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxn+
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/H

 MP:0011968 decreased threshold for auditory brainstem response "reduction in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system" [MGI:csmith]
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Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0012765 decreased alpha-beta T cell number "reduced number of T cells that expresses an alpha-beta T cell receptor complex" [CL:0000789]
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Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0013916 decreased intestine length "reduced length of the digestive tube passing from the stomach to the anus, consisting of the small and large intestine divisions" [ISBN:0-683-40008-8]
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Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

 MP:0013986 abnormal vitelline vein topology "abnormal position of the paired veins that carry blood from the yolk sac back to the embryo" [MGI:csmith]
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Allelic Composition: Nxntm1b(EUCOMM)Wtsi/Nxntm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1b(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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