ENSMUSG00000021396


Mus musculus

Features
Gene ID: ENSMUSG00000021396
  
Biological name :Nxnl2
  
Synonyms : Nucleoredoxin-like protein 2 / Nxnl2 / Q9D531
  
Possible biological names infered from orthology : nucleoredoxin like 2 / Q5VZ03
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A5
Gene start: 51171022
Gene end: 51175188
  
Corresponding Affymetrix probe sets: 10405174 (MoGene1.0st)   1429133_at (Mouse Genome 430 2.0 Array)   1451861_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021828
NCBI entrez gene - 75124     See in Manteia.
MGI - MGI:1922374
RefSeq - XM_006516962
RefSeq - NM_029173
RefSeq - XM_006516960
RefSeq - XM_006516961
RefSeq - XM_006516959
RefSeq Peptide - NP_083449
swissprot - Q9D531
Ensembl - ENSMUSG00000021396
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nxnl2ENSDARG00000003934Danio rerio
 ENSGALG00000046525Gallus gallus
 ENSGALG00000026598Gallus gallus
 NXNL2ENSG00000130045Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nxnl1 / Q8VC33 / Nucleoredoxin-like protein 1 / Q96CM4* / nucleoredoxin like 1*ENSMUSG0000003482937
Nxn / P97346 / Nucleoredoxin / Q6DKJ4*ENSMUSG0000002084429


Protein motifs (from Interpro)
Interpro ID Name
 IPR012336  Thioredoxin-like fold
 IPR029519  Nucleoredoxin-like protein 2
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007600 sensory perception IEA
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0007608 sensory perception of smell IMP
 biological_processGO:0045494 photoreceptor cell maintenance IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004791 thioredoxin-disulfide reductase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Lrp2tm3Tew/Lrp2tm3Tew
Genetic Background: Not Specified

 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Lrp2tm3Tew/Lrp2tm3Tew
Genetic Background: Not Specified

 MP:0006092 abnormal olfactory neuron morphology "malformation in the neurons that are activated by specific odorants" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92950]
Show

Allelic Composition: Lrp2tm3Tew/Lrp2tm3Tew
Genetic Background: Not Specified

 MP:0008446 decreased retinal cone cell number "reduced number of one of the photoreceptor cell types in the retina, in which the photopigment is in invaginations of the cell membrane of the outer segment" [MESH:A08.663.650.650.670.100, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lrp2tm3Tew/Lrp2tm3Tew
Genetic Background: Not Specified

 MP:0008544 impaired olfaction "reduced ability to detect odors" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lrp2tm3Tew/Lrp2tm3Tew
Genetic Background: Not Specified

 MP:0008587 short photoreceptor outer segment "decreased length of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lrp2tm3Tew/Lrp2tm3Tew
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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