ENSMUSG00000020883


Mus musculus

Features
Gene ID: ENSMUSG00000020883
  
Biological name :Fbxl20
  
Synonyms : F-box/LRR-repeat protein 20 / Fbxl20 / Q9CZV8
  
Possible biological names infered from orthology : F-box and leucine rich repeat protein 20 / Q96IG2
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 98082556
Gene end: 98150403
  
Corresponding Affymetrix probe sets: 10390574 (MoGene1.0st)   1418419_at (Mouse Genome 430 2.0 Array)   1442464_at (Mouse Genome 430 2.0 Array)   1452826_s_at (Mouse Genome 430 2.0 Array)   1456378_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099432
Ensembl peptide - ENSMUSP00000123507
Ensembl peptide - ENSMUSP00000120709
Ensembl peptide - ENSMUSP00000119003
NCBI entrez gene - 72194     See in Manteia.
MGI - MGI:1919444
RefSeq - XM_006534298
RefSeq - XM_006534300
RefSeq - XM_006534299
RefSeq - NM_028149
RefSeq Peptide - NP_082425
swissprot - Q9CZV8
swissprot - A2A550
swissprot - A2A533
swissprot - A2A536
Ensembl - ENSMUSG00000020883
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxl20ENSDARG00000075567Danio rerio
 FBXL20ENSGALG00000001682Gallus gallus
 FBXL20ENSG00000108306Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fbxl2 / Q8BH16 / F-box/LRR-repeat protein 2 / Q9UKC9* / F-box and leucine rich repeat protein 2*ENSMUSG0000003250774
Fbxl7 / Q5BJ29 / F-box/LRR-repeat protein 7 / Q9UJT9* / F-box and leucine rich repeat protein 7*ENSMUSG0000004355628
Fbxl13 / Q8CDU4 / F-box/LRR-repeat protein 13 / Q8NEE6* / F-box and leucine rich repeat protein 13*ENSMUSG0000004852025
Fbxl17 / Q9QZN1 / F-box/LRR-repeat protein 17 / Q9UF56* / F-box and leucine rich repeat protein 17*ENSMUSG0000002396523
A2RT62 / Fbxl16 / F-box/LRR-repeat protein 16 / Q8N461* / F-box and leucine rich repeat protein 16*ENSMUSG0000002573821
Fbxl14 / Q8BID8 / F-box/LRR-repeat protein 14 / Q8N1E6* / F-box and leucine rich repeat protein 14*ENSMUSG0000003001921
Fbxl4 / Q8BH70 / F-box/LRR-repeat protein 4 / Q9UKA2* / F-box and leucine rich repeat protein 4*ENSMUSG0000004041020
Fbxl15 / Q91W61 / F-box/LRR-repeat protein 15 / Q9H469* / F-box and leucine rich repeat protein 15*ENSMUSG0000002522616
Lrrc29 / leucine rich repeat containing 29 / Q8WV35*ENSMUSG000000416798


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR001810  F-box domain
 IPR006553  Leucine-rich repeat, cysteine-containing subtype
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001662 behavioral fear response IMP
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Ap3d1mh-2J/Ap3d1mh-2J
Genetic Background: involves: C3H/HeJ * C57BL/6J

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ap3d1mh-2J/Ap3d1mh-2J
Genetic Background: involves: C3H/HeJ * C57BL/6J

 MP:0002920 reduced paired-pulse facilitation "decrease in the response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to lack of increase of neurotransmitter release at the second stimulus" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Ap3d1mh-2J/Ap3d1mh-2J
Genetic Background: involves: C3H/HeJ * C57BL/6J

 MP:0004247 small pancreas "decrease of the size of the pancreas compared to controls" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Ap3d1mh-2J/Ap3d1mh-2J
Genetic Background: involves: C3H/HeJ * C57BL/6J

 MP:0004753 abnormal miniature excitatory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Ap3d1mh-2J/Ap3d1mh-2J
Genetic Background: involves: C3H/HeJ * C57BL/6J

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Ap3d1mh-2J/Ap3d1mh-2J
Genetic Background: involves: C3H/HeJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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