| MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0000154 | rib fusion | "appearance of one or more ribs as a single structure" [J:62022, J:62023] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0000284 | double outlet right ventricle | "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0000379 | reduced hair follicle number | "fewer number of the epidermal invaginations from which the hair shaft develops" [J:15108] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0001243 | abnormal dermal layer morphology | "malformed or atypical condition of the dermal layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:56777] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0001244 | thin dermal layer | "reduced thickness of the dermis" [J:65030] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0001297 | microphthalmia | "reduced average size of the eyes" [J:18048] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0001303 | abnormal lens morphology | "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0001312 | abnormal cornea morphology | "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0001319 | irregularly shaped pupil | "shape defects in the aperture of the iris through which light rays enter the eye, usually circular " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0001325 | abnormal retina morphology | "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Pfn1tm1a(EUCOMM)Wtsi/Pfn1+
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd Pfn1tm1a(EUCOMM)Wtsi/Wtsi
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| MP:0001693 | failure of primitive streak formation | "inability to form the epiblast ridge from which arises the germ layers of the embryo" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:33880] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0001696 | failure to gastrulate | "inability to differentiate and invaginate the primary germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:34458] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0001780 | decreased brown fat amount | "reduced quantity of this thermogenic form of adipose tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0001785 | edema | "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0002633 | persistent truncus arteriosis | "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0003984 | embryonic growth retardation | "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0004110 | transposition of great arteries | "cardiovascular malformation in which the aorta arises from the right ventricle while the pulmonary artery arises from the left ventricle" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0004616 | lumbar vertebral transformation | "homeotic transformation of any lumbar vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0005300 | abnormal corneal stroma morphology | "structural anomaly of the lamellated connective tissue of the cornea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0006126 | abnormal outflow tract development | "anomaly in the development of the common arterial trunk that forms the aorta and pulmonary artery" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0010402 | ventricular septal defect | "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0011094 | complete embryonic lethality before implantation | "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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| MP:0011100 | complete preweaning lethality | "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Pfn1tm1a(EUCOMM)Wtsi/Pfn1+
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd Pfn1tm1a(EUCOMM)Wtsi/Wtsi
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| MP:0013292 | embryonic lethality prior to organogenesis | "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb] |
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Allelic Composition: Pfn1tm1a(EUCOMM)Wtsi/Pfn1+
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd Pfn1tm1a(EUCOMM)Wtsi/Wtsi
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| MP:0013293 | embryonic lethality prior to tooth bud stage | "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb] |
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Allelic Composition: Pfn1tm1a(EUCOMM)Wtsi/Pfn1+
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd Pfn1tm1a(EUCOMM)Wtsi/Wtsi
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