ENSMUSG00000021000


Mus musculus

Features
Gene ID: ENSMUSG00000021000
  
Biological name :Mia2
  
Synonyms : Mia2 / Mus musculus melanoma inhibitory activity 2 (Mia2), transcript variant 1, mRNA. / Q91ZV0
  
Possible biological names infered from orthology : A4D2H0 / A4FU28 / CTAGE1 / CTAGE15 / CTAGE4 / CTAGE5 / CTAGE6 / CTAGE8 / CTAGE9 / CTAGE family member 15 / CTAGE family member 4 / CTAGE family member 5, ER export factor / CTAGE family member 6 / CTAGE family member 8 / CTAGE family member 9 / cutaneous T cell lymphoma-associated antigen 1 / O15320 / P0CG41 / Q86UF2 / Q8IX94 / Q96PC5 / Q96RT6 / Q9HC47
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: C1
Gene start: 59095799
Gene end: 59191583
  
Corresponding Affymetrix probe sets: 10395925 (MoGene1.0st)   10395932 (MoGene1.0st)   1426445_at (Mouse Genome 430 2.0 Array)   1451964_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135618
Ensembl peptide - ENSMUSP00000135440
Ensembl peptide - ENSMUSP00000135694
Ensembl peptide - ENSMUSP00000151482
Ensembl peptide - ENSMUSP00000021384
Ensembl peptide - ENSMUSP00000070572
Ensembl peptide - ENSMUSP00000126538
Ensembl peptide - ENSMUSP00000134828
Ensembl peptide - ENSMUSP00000134872
Ensembl peptide - ENSMUSP00000134887
Ensembl peptide - ENSMUSP00000134972
Ensembl peptide - ENSMUSP00000135001
Ensembl peptide - ENSMUSP00000135100
Ensembl peptide - ENSMUSP00000135105
Ensembl peptide - ENSMUSP00000135179
Ensembl peptide - ENSMUSP00000135245
Ensembl peptide - ENSMUSP00000135251
Ensembl peptide - ENSMUSP00000135390
NCBI entrez gene - 338320     See in Manteia.
MGI - MGI:2159614
RefSeq - NM_001329047
RefSeq - NM_001165253
RefSeq - NM_001165254
RefSeq - NM_146034
RefSeq - NM_177321
RefSeq - XM_006515677
RefSeq - XM_006515678
RefSeq - XM_006515679
RefSeq - XM_006515680
RefSeq Peptide - NP_001158725
RefSeq Peptide - NP_001158726
RefSeq Peptide - NP_001315976
RefSeq Peptide - NP_796295
RefSeq Peptide - NP_666146
swissprot - H3BL86
swissprot - E9PY90
swissprot - A0A1W2P711
swissprot - Q91ZV0
swissprot - E9Q3S2
swissprot - H3BJ35
swissprot - H3BJ71
swissprot - H3BJ84
swissprot - H3BJI6
swissprot - H3BJS0
swissprot - H3BJS5
swissprot - H3BK44
swissprot - H3BJY7
swissprot - H3BK48
swissprot - H3BKH2
swissprot - H3BKL6
swissprot - H3BL19
Ensembl - ENSMUSG00000021000
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU469462.1ENSDARG00000099973Danio rerio
 ENSGALG00000010189Gallus gallus
 A4D2H0ENSG00000271079Homo sapiens
 A4FU28ENSG00000236761Homo sapiens
 CTAGE1ENSG00000212710Homo sapiens
 CTAGE4ENSG00000225932Homo sapiens
 CTAGE5ENSG00000150527Homo sapiens
 CTAGE6ENSG00000271321Homo sapiens
 CTAGE8ENSG00000244693Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mia3 / transport and Golgi organization / Q5JRA6* / MIA family member 3, ER export factor*ENSMUSG0000005605025


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042632 cholesterol homeostasis IMP
 biological_processGO:0042953 lipoprotein transport IEA
 biological_processGO:0070328 triglyceride homeostasis IMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070971 endoplasmic reticulum exit site ISO
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042954 lipoprotein transporter activity ISS


Pathways (from Reactome)
Pathway description
Cargo concentration in the ER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000186 decreased circulating HDL cholesterol level "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Smn1tm2Cdid/Smn1tm2Cdid
Genetic Background: involves: 129 * C57BL/6

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Smn1tm2Cdid/Smn1tm2Cdid
Genetic Background: involves: 129 * C57BL/6

 MP:0003976 decreased circulating VLDL triglyceride level "lower than average concentration in the blood of very low density lipoprotein, which normally transports triglycerides from the intestine and liver to muscle and adipose tissue" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Smn1tm2Cdid/Smn1tm2Cdid
Genetic Background: involves: 129 * C57BL/6

 MP:0005179 decreased total circulating cholesterol level "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Smn1tm2Cdid/Smn1tm2Cdid
Genetic Background: involves: 129 * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020986 Q01405 / Sec23a / Protein transport protein Sec23A / Q15436* / Sec23 homolog A, coat complex II component*  / reaction / complex
 ENSMUSG00000045302 Preb / Q9WUQ2 / prolactin regulatory element binding / Q9HCU5*  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr