ENSMUSG00000021143


Mus musculus

Features
Gene ID: ENSMUSG00000021143
  
Biological name :Pacs2
  
Synonyms : Pacs2 / phosphofurin acidic cluster sorting protein 2 / Q3V3Q7
  
Possible biological names infered from orthology : Q86VP3
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: F1
Gene start: 113014508
Gene end: 113074401
  
Corresponding Affymetrix probe sets: 10398936 (MoGene1.0st)   10398966 (MoGene1.0st)   1426963_at (Mouse Genome 430 2.0 Array)   1434255_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152250
Ensembl peptide - ENSMUSP00000152439
Ensembl peptide - ENSMUSP00000081953
Ensembl peptide - ENSMUSP00000152145
NCBI entrez gene - 217893     See in Manteia.
MGI - MGI:1924399
RefSeq - XM_006515779
RefSeq - XM_006515770
RefSeq - XM_006515771
RefSeq - XM_006515772
RefSeq - XM_006515773
RefSeq - XM_006515774
RefSeq - XM_006515777
RefSeq - XM_006515778
RefSeq - NM_001081170
RefSeq - NM_001291444
RefSeq - NM_001291445
RefSeq - XM_006515769
RefSeq Peptide - NP_001278374
RefSeq Peptide - NP_001074639
RefSeq Peptide - NP_001278373
swissprot - A0A1Y7VLZ7
swissprot - Q3V3Q7
swissprot - A0A1Y7VN58
swissprot - E9Q7E9
Ensembl - ENSMUSG00000021143
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pacs2ENSDARG00000078185Danio rerio
 PACS2ENSGALG00000033328Gallus gallus
 PACS2ENSG00000179364Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pacs1 / Q8K212 / Phosphofurin acidic cluster sorting protein 1 / Q6VY07*ENSMUSG0000002485555


Protein motifs (from Interpro)
Interpro ID Name
 IPR019381  Phosphofurin acidic cluster sorting protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0034497 protein localization to phagophore assembly site IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 molecular_functionGO:0044325 ion channel binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp

 MP:0003638 abnormal response/metabolism to endogenous compounds "altered ability or inability to metabolize or respond to substances normally present in the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rps28GT(RNA3)Whk/Rps28GT(RNA3)Whk
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp

 MP:0006043 decreased apoptosis "less than normal cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rps28GT(RNA3)Whk/Rps28GT(RNA3)Whk
Genetic Background: involves: 129S7/SvEvBrd

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr