ENSMUSG00000021368


Mus musculus

Features
Gene ID: ENSMUSG00000021368
  
Biological name :Tbc1d7
  
Synonyms : Q9D0K0 / Tbc1d7 / TBC1 domain family member 7
  
Possible biological names infered from orthology : Q9P0N9
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A4
Gene start: 43151740
Gene end: 43171501
  
Corresponding Affymetrix probe sets: 10408870 (MoGene1.0st)   1428598_at (Mouse Genome 430 2.0 Array)   1457436_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152072
Ensembl peptide - ENSMUSP00000152737
Ensembl peptide - ENSMUSP00000152443
Ensembl peptide - ENSMUSP00000152358
Ensembl peptide - ENSMUSP00000152208
Ensembl peptide - ENSMUSP00000152162
Ensembl peptide - ENSMUSP00000021797
Ensembl peptide - ENSMUSP00000137280
NCBI entrez gene - 67046     See in Manteia.
MGI - MGI:1914296
RefSeq - XM_006516945
RefSeq - NM_001252639
RefSeq - NM_001252640
RefSeq - NM_025935
RefSeq Peptide - NP_080211
RefSeq Peptide - NP_001239568
RefSeq Peptide - NP_001239569
swissprot - A0A1Y7VKU8
swissprot - A0A1Y7VJF2
swissprot - A0A1Y7VM03
swissprot - A0A1Y7VIN4
swissprot - Q9D0K0
swissprot - A0A1Y7VN27
Ensembl - ENSMUSG00000021368
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F1QRX7ENSDARG00000029581Danio rerio
 TBC1D7ENSGALG00000012731Gallus gallus
 Q9P0N9ENSG00000145979Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031398 positive regulation of protein ubiquitination ISO
 biological_processGO:0032007 negative regulation of TOR signaling ISO
 biological_processGO:0043547 positive regulation of GTPase activity ISO
 biological_processGO:0070848 response to growth factor ISO
 biological_processGO:0090630 activation of GTPase activity ISO
 biological_processGO:1902018 negative regulation of cilium assembly ISO
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 cellular_componentGO:0036064 ciliary basal body ISO
 molecular_functionGO:0005096 GTPase activator activity ISO
 molecular_functionGO:0017137 Rab GTPase binding ISO


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026812 Tsc1 / Q9EP53 / Hamartin / Q92574* / TSC complex subunit 1*  / reaction / complex
 ENSMUSG00000002496 Tsc2 / tuberous sclerosis 2 / P49815* / TSC complex subunit 2*  / reaction / complex






 

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contact: otassy@igbmc.fr