ENSMUSG00000021373


Mus musculus

Features
Gene ID: ENSMUSG00000021373
  
Biological name :Cap2
  
Synonyms : Adenylyl cyclase-associated protein 2 / Cap2 / Q9CYT6
  
Possible biological names infered from orthology : cyclase associated actin cytoskeleton regulatory protein 2 / P40123
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A5
Gene start: 46501848
Gene end: 46650281
  
Corresponding Affymetrix probe sets: 10404913 (MoGene1.0st)   1423222_at (Mouse Genome 430 2.0 Array)   1450910_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021802
Ensembl peptide - ENSMUSP00000153125
Ensembl peptide - ENSMUSP00000153072
Ensembl peptide - ENSMUSP00000112952
NCBI entrez gene - 67252     See in Manteia.
MGI - MGI:1914502
RefSeq - XM_006516946
RefSeq - NM_026056
RefSeq Peptide - NP_080332
swissprot - A0A286YCS6
swissprot - D3YTR7
swissprot - Q9CYT6
swissprot - A0A286YCN6
Ensembl - ENSMUSG00000021373
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cap2ENSDARG00000104478Danio rerio
 CAP2ENSGALG00000012715Gallus gallus
 CAP2ENSG00000112186Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cap1 / P40124 / Mus musculus CAP, adenylate cyclase-associated protein 1 (yeast) (Cap1), transcript variant 3, mRNA. / Q01518* / cyclase associated actin cytoskeleton regulatory protein 1*ENSMUSG0000002865662


Protein motifs (from Interpro)
Interpro ID Name
 IPR001837  Adenylate cyclase-associated CAP
 IPR006599  CARP motif
 IPR013912  Adenylate cyclase-associated CAP, C-terminal
 IPR013992  Adenylate cyclase-associated CAP, N-terminal
 IPR017901  C-CAP/cofactor C-like domain
 IPR018106  CAP, conserved site, N-terminal
 IPR028417  CAP, conserved site, C-terminal
 IPR028418  Adenylyl cyclase-associated protein CAP2
 IPR036222  Adenylate cyclase-associated CAP, N-terminal domain superfamily
 IPR036223  Adenylate cyclase-associated CAP, C-terminal superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IBA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007163 establishment or maintenance of cell polarity IBA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0008154 actin polymerization or depolymerization IBA
 biological_processGO:0045761 regulation of adenylate cyclase activity IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IBA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0008179 adenylate cyclase binding IBA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
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Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0000278 abnormal myocardial fiber morphology "malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048]
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Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0000565 oligodactyly "congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Cacna1btm1b(KOMP)Wtsi/Cacna1btm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Cacna1btm1b(KOMP)Wtsi/H

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Btktm1a(EUCOMM)Hmgu/Y
Genetic Background: C57BL/6N-Btktm1a(EUCOMM)Hmgu/Ics

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1a(EUCOMM)Wtsi/Ieg

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: Btktm1a(EUCOMM)Hmgu/Y
Genetic Background: C57BL/6N-Btktm1a(EUCOMM)Hmgu/Ics

 MP:0001320 small pupils "smaller than normal size of the central circular aperture of the iris through which light rays enter the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0001851 eye inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the eye" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm4(CAG-hsb5)Nki/Gt(ROSA)26Sor+,Tg(Mx1-cre)1Cgn/0,Tg(tetO-BCR/ABL1)2Dgt/0,TgTn(pb-sb-GrOnc)#aGsva/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA/J * FVB/N

Allelic Composition: Cap2tm1c(EUCOMM)Wtsi/Cap2tm1c(EUCOMM)Wtsi,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0002406 increased susceptibility to infection "greater likelihood that an organism will develop ill effects from a pathogenic invasion or from components of or toxins produced by pathogens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1a(EUCOMM)Wtsi/Ieg

 MP:0002753 dilated left ventricle "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0002795 dilated cardiomyopathy "decreased function of the heart associated with cardiac enlargement and congestive heart failure" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0003061 decreased aerobic running capacity "reduced ability to run at defined speeds and/or distances compared to controls" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0003137 abnormal impulse conducting system conduction "anomaly in the impulse-conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart" [hdene:Howard Dene , Mouse Genome Informatics Curator, J:92050, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1c(EUCOMM)Wtsi/Cap2tm1c(EUCOMM)Wtsi,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0003140 dilated atria "an expansion in the volume of one or both of the upper chambers of the heart" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0003141 cardiac fibrosis "formation of fibrous tissue within the heart often resulting from inflammation or injury " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0003233 prolonged QT interval "increase in the length of time required for ventricular depolarization and repolarization to occur, usually as a result of increased repolarization time" [J:93197, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0003313 abnormal locomotor activation "altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Btktm1a(EUCOMM)Hmgu/Y
Genetic Background: C57BL/6N-Btktm1a(EUCOMM)Hmgu/Ics

 MP:0004062 dilated right atrium "an expansion in the volume of the right upper chamber of the heart" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0004090 abnormal sarcomere morphology "any structural abnormality in the segment of a myofibril between two Z lines comprised of multi-protein complexes composed of three different filament systems; these systems work together to contract and relax muscle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0004094 abnormal M lines "any structural anomaly in the band in the center of the H band that contains proteins that crosslink the thick filament system (myosins) and the M-band part of the elastic filaments" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0004215 abnormal myocardial fiber physiology "anomaly in the function of the multinucleated muscle cells of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0004567 decreased myocardial fiber number "decreased number of cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0005329 abnormal cardiac muscle morphology "anomalous structure of the involuntary muscle comprising the myocardium " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0005333 decreased heart rate "fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84764]
Show

Allelic Composition: Cap2tm1c(EUCOMM)Wtsi/Cap2tm1c(EUCOMM)Wtsi,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0005598 decreased ventricle muscle contractility "reduced ability of the heart ventricle muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0005608 cardiac interstitial fibrosis "formation of fibrous tissue within the interstices of the heart as a result of repair or a reactive process" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0006138 congestive heart failure "the heart is unable to adequately pump blood throughout the body" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0008022 dilated heart ventricles "the lumenal space of the lower chambers of the heart is increased in volume or area, usually with an increase in contained fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2+
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0010392 prolonged QRS complex duration "increase in the length of time of the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarize prior to their contraction; prolongation of the QRS complex duration reflects slowed conduction in the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1c(EUCOMM)Wtsi/Cap2tm1c(EUCOMM)Wtsi,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0010499 abnormal ventricle myocardium morphology "any structural anomaly of the ventricular part of middle layer of the heart, comprised of involuntary muscle" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0010506 prolonged RR interval "increase in the length of the interval between an R wave and the next R wave; the RR interval is the inverse of the heart rate" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cap2tm1c(EUCOMM)Wtsi/Cap2tm1c(EUCOMM)Wtsi,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0010519 atrioventricular block "a partial or complete obstruction of the impulse that originates in the atria or sinoatrial node from reaching or transmitting through the atrioventricular node to the ventricles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Cap2tm1c(EUCOMM)Wtsi/Cap2tm1c(EUCOMM)Wtsi,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0010553 prolonged HV interval "increase in the length of time from the initial deflection of the His bundle (H) potential and the onset of ventricular activity" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1c(EUCOMM)Wtsi/Cap2tm1c(EUCOMM)Wtsi,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0010637 sinus bradycardia "a type of decreased heart rhythm in which fewer than the normal number of impulses arise from the sinoatrial (SA) node" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Cap2tm1c(EUCOMM)Wtsi/Cap2tm1c(EUCOMM)Wtsi,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Cap2tm1a(EUCOMM)Wtsi/Cap2tm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Cacna1btm1b(KOMP)Wtsi/Cacna1btm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Cacna1btm1b(KOMP)Wtsi/H

 MP:0011953 prolonged PQ interval "increase in the length of time between the beginning of atrial depolarization and the end of atrial repolarization (or recovery), measured by the interval from the beginning of the P wave to the end of the Q wave" [MPD:Molly]
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Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

 MP:0030567 abnormal I band morphology "any structural anomaly of the light band on each side of the Z disc (aka Z line), comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; the I band is isotropic to polarized light and contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end" [GO:0031674, https://en.wikipedia.org/wiki/Sarcomere]
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Allelic Composition: Cap2tm1e(EUCOMM)Wtsi/Cap2tm1e(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cap2tm1e(EUCOMM)Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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