ENSMUSG00000028656


Mus musculus

Features
Gene ID: ENSMUSG00000028656
  
Biological name :Cap1
  
Synonyms : Cap1 / Mus musculus CAP, adenylate cyclase-associated protein 1 (yeast) (Cap1), transcript variant 3, mRNA. / P40124
  
Possible biological names infered from orthology : cyclase associated actin cytoskeleton regulatory protein 1 / Q01518
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D2.2
Gene start: 122859047
Gene end: 122886056
  
Corresponding Affymetrix probe sets: 10516051 (MoGene1.0st)   1417461_at (Mouse Genome 430 2.0 Array)   1417462_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000068260
Ensembl peptide - ENSMUSP00000101862
Ensembl peptide - ENSMUSP00000101864
Ensembl peptide - ENSMUSP00000114847
NCBI entrez gene - 12331     See in Manteia.
MGI - MGI:88262
RefSeq - XM_006502697
RefSeq - NM_001301067
RefSeq - NM_001358035
RefSeq - NM_001358036
RefSeq - NM_007598
RefSeq - XM_006502695
RefSeq Peptide - NP_001344964
RefSeq Peptide - NP_001344965
RefSeq Peptide - NP_031624
RefSeq Peptide - NP_001287996
swissprot - P40124
swissprot - B1ARS0
Ensembl - ENSMUSG00000028656
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cap1ENSDARG00000016350Danio rerio
 CAP1ENSGALG00000036294Gallus gallus
 CAP1ENSG00000131236Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cap2 / Q9CYT6 / Adenylyl cyclase-associated protein 2 / P40123* / cyclase associated actin cytoskeleton regulatory protein 2*ENSMUSG0000002137363


Protein motifs (from Interpro)
Interpro ID Name
 IPR001837  Adenylate cyclase-associated CAP
 IPR006599  CARP motif
 IPR013912  Adenylate cyclase-associated CAP, C-terminal
 IPR013992  Adenylate cyclase-associated CAP, N-terminal
 IPR017901  C-CAP/cofactor C-like domain
 IPR018106  CAP, conserved site, N-terminal
 IPR028415  Adenylyl cyclase-associated protein CAP1
 IPR028417  CAP, conserved site, C-terminal
 IPR036222  Adenylate cyclase-associated CAP, N-terminal domain superfamily
 IPR036223  Adenylate cyclase-associated CAP, C-terminal superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IGI
 biological_processGO:0001667 ameboidal-type cell migration IMP
 biological_processGO:0006898 receptor-mediated endocytosis IMP
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007163 establishment or maintenance of cell polarity IBA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0008154 actin polymerization or depolymerization IBA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0045761 regulation of adenylate cyclase activity IBA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008179 adenylate cyclase binding IBA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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