ENSMUSG00000021470


Mus musculus

Features
Gene ID: ENSMUSG00000021470
  
Biological name :Ercc6l2
  
Synonyms : DNA excision repair protein ERCC-6-like 2 / Ercc6l2 / Q9JIM3
  
Possible biological names infered from orthology : ERCC excision repair 6 like 2 / Q5T890
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: B3
Gene start: 63815240
Gene end: 63900302
  
Corresponding Affymetrix probe sets: 10405785 (MoGene1.0st)   10405804 (MoGene1.0st)   1427836_at (Mouse Genome 430 2.0 Array)   1452447_at (Mouse Genome 430 2.0 Array)   1452573_a_at (Mouse Genome 430 2.0 Array)   1453985_at (Mouse Genome 430 2.0 Array)   1460404_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152142
Ensembl peptide - ENSMUSP00000115796
Ensembl peptide - ENSMUSP00000124912
Ensembl peptide - ENSMUSP00000021925
Ensembl peptide - ENSMUSP00000021926
Ensembl peptide - ENSMUSP00000069488
Ensembl peptide - ENSMUSP00000093392
NCBI entrez gene - 76251     See in Manteia.
MGI - MGI:1923501
RefSeq - XM_017315633
RefSeq - NM_001013608
RefSeq - NM_023507
RefSeq - XM_006517450
RefSeq - XM_006517451
RefSeq - XM_017315632
RefSeq Peptide - NP_001013626
RefSeq Peptide - NP_075996
swissprot - F6TW36
swissprot - G8JL31
swissprot - F6SJP9
swissprot - Q9JIM3
swissprot - E9QPI9
Ensembl - ENSMUSG00000021470
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ercc6l2ENSDARG00000012403Danio rerio
 Q5T890ENSG00000182150Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ercc6 / ERCC excision repair 6, chromatin remodeling factor / P0DP91* / Q03468* / Q8N328*ENSMUSG0000005405128
Ercc6l / Q8BHK9 / DNA excision repair protein ERCC-6-like / Q2NKX8* / ERCC excision repair 6 like, spindle assembly checkpoint helicase*ENSMUSG0000005122027


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0034614 cellular response to reactive oxygen species ISO
 biological_processGO:0036297 interstrand cross-link repair ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019901 protein kinase binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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