ENSMUSG00000021759


Mus musculus

Features
Gene ID: ENSMUSG00000021759
  
Biological name :Plpp1
  
Synonyms : Phospholipid phosphatase 1 / Plpp1 / Q61469
  
Possible biological names infered from orthology : O14494
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: D2.2
Gene start: 112800792
Gene end: 112867894
  
Corresponding Affymetrix probe sets: 10407211 (MoGene1.0st)   1422619_at (Mouse Genome 430 2.0 Array)   1422620_s_at (Mouse Genome 430 2.0 Array)   1425449_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000016144
Ensembl peptide - ENSMUSP00000064423
NCBI entrez gene - 19012     See in Manteia.
MGI - MGI:108412
RefSeq - NM_008247
RefSeq - NM_008903
RefSeq Peptide - NP_032273
RefSeq Peptide - NP_032929
swissprot - Q61469
Ensembl - ENSMUSG00000021759
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO018102.1ENSDARG00000079790Danio rerio
 plpp1aENSDARG00000053381Danio rerio
 PLPP1ENSGALG00000014711Gallus gallus
 PLPP1ENSG00000067113Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Plpp2 / Q9DAX2 / phospholipid phosphatase 2 / O43688*ENSMUSG0000005215151
Plpp3 / Q99JY8 / Phospholipid phosphatase 3 / O14495* / AC119674.2*ENSMUSG0000002851745
Plppr4 / Q7TME0 / Phospholipid phosphatase-related protein type 4 / Q7Z2D5* / phospholipid phosphatase related 4*ENSMUSG0000004466729
Plppr3 / phospholipid phosphatase related 3 / Q6T4P5*ENSMUSG0000003583526
Plppr1 / Q8BFZ2 / Phospholipid phosphatase-related protein type 1 / Q8TBJ4* / phospholipid phosphatase related 1*ENSMUSG0000006344626
Plppr5 / Q8BJ52 / Phospholipid phosphatase-related protein type 5 / Q32ZL2* / phospholipid phosphatase related 5*ENSMUSG0000003334224
Plppr2 / Q8VCY8 / Phospholipid phosphatase-related protein type 2 / Q96GM1* / phospholipid phosphatase related 2*ENSMUSG0000004056323


Protein motifs (from Interpro)
Interpro ID Name
 IPR000326  Phosphatidic acid phosphatase type 2/haloperoxidase
 IPR028670  Lipid phosphate phosphohydrolase 1
 IPR036938  Phosphatidic acid phosphatase type 2/haloperoxidase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation TAS
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process IBA
 biological_processGO:0006651 diacylglycerol biosynthetic process TAS
 biological_processGO:0006670 sphingosine metabolic process TAS
 biological_processGO:0006672 ceramide metabolic process TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0046839 phospholipid dephosphorylation IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008195 phosphatidate phosphatase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042577 lipid phosphatase activity IBA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0009642 abnormal blood homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gpr68tm1Yaxu/Gpr68tm1Yaxu
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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