ENSMUSG00000021792


Mus musculus

Features
Gene ID: ENSMUSG00000021792
  
Biological name :Fam213a
  
Synonyms : Fam213a / Q9CYH2 / Redox-regulatory protein FAM213A
  
Possible biological names infered from orthology : family with sequence similarity 213 member A / Q9BRX8
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: B
Gene start: 40993740
Gene end: 41013788
  
Corresponding Affymetrix probe sets: 10419082 (MoGene1.0st)   1435496_at (Mouse Genome 430 2.0 Array)   1447774_x_at (Mouse Genome 430 2.0 Array)   1452716_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115839
Ensembl peptide - ENSMUSP00000115439
Ensembl peptide - ENSMUSP00000117278
Ensembl peptide - ENSMUSP00000123109
Ensembl peptide - ENSMUSP00000122866
Ensembl peptide - ENSMUSP00000121795
Ensembl peptide - ENSMUSP00000120052
Ensembl peptide - ENSMUSP00000022317
Ensembl peptide - ENSMUSP00000112377
NCBI entrez gene - 70564     See in Manteia.
MGI - MGI:1917814
RefSeq - XM_006519531
RefSeq - NM_001316732
RefSeq - NM_001316733
RefSeq - NM_001316734
RefSeq - NM_001316735
RefSeq - NM_001316736
RefSeq - NM_001316737
RefSeq - NM_001316739
RefSeq - NM_001316740
RefSeq - NM_027464
RefSeq Peptide - NP_001303669
RefSeq Peptide - NP_081740
RefSeq Peptide - NP_001303661
RefSeq Peptide - NP_001303662
RefSeq Peptide - NP_001303663
RefSeq Peptide - NP_001303664
RefSeq Peptide - NP_001303665
RefSeq Peptide - NP_001303666
RefSeq Peptide - NP_001303668
swissprot - D3Z252
swissprot - Q3U125
swissprot - Q9CYH2
swissprot - D3YWL4
swissprot - D3Z143
swissprot - D3Z0A8
swissprot - D3YYG8
swissprot - D3Z398
Ensembl - ENSMUSG00000021792
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO017725.1ENSDARG00000117204Danio rerio
 Q6PBP3ENSDARG00000057378Danio rerio
 selenou1bENSDARG00000087059Danio rerio
 SELENOUENSGALG00000002421Gallus gallus
 Q9BRX8ENSG00000122378Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9DB60 / Fam213b / Prostamide/prostaglandin F synthase / Q8TBF2* / family with sequence similarity 213 member B*ENSMUSG0000002905919


Protein motifs (from Interpro)
Interpro ID Name
 IPR032801  Peroxiredoxin-like FAM213/AAED1
 IPR032802  Peroxiredoxin-like FAM213A
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045670 regulation of osteoclast differentiation IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016209 antioxidant activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Juptm1.1Chen/Juptm1.1Chen
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

 MP:0004892 increased adiponectin level "greater level of a protein hormone that regulates glucose homeostasis and metabolism of lipids; it is normally produced by adipose tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Juptm1.1Chen/Juptm1.1Chen
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

 MP:0004893 decreased adiponectin level "reduced concentration of a protein hormone that regulates glucose homeostasis and metabolism of lipids; it is normally produced by adipose tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Juptm1.1Chen/Juptm1.1Chen
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

 MP:0006319 abnormal epididymal fat pad "any structural anomaly of the encapsulated adipose tissue associated with the epididymis" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Juptm1.1Chen/Juptm1.1Chen
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

 MP:0020254 decreased collagen level "decreased level of the main structural protein of the various connective tissues in animals" [GOC:NV, PMID:11704682]
Show

Allelic Composition: Juptm1.1Chen/Juptm1.1Chen
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

 MP:0020354 increased endoplasmic reticulum stress "increase in in the accumulation of misfolded or unfolded proteins in the endoplasmic reticulum lumen; this accumulation may be stimulated by genetic or enviromental factors" [ORCID: orcid.org/0000-0003-4606-0597]
Show

Allelic Composition: Juptm1.1Chen/Juptm1.1Chen
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

 MP:0020386 adipose tissue inflammation "local accumulation of fluid, plasma proteins, and leukocytes in adipose tissue" [MGI:anna, PMID:24662293, PMID:24695736, PMID:26629401]
Show

Allelic Composition: Juptm1.1Chen/Juptm1.1Chen
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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