ENSMUSG00000021962


Mus musculus

Features
Gene ID: ENSMUSG00000021962
  
Biological name :Dcp1a
  
Synonyms : Dcp1a / mRNA-decapping enzyme 1A / Q91YD3
  
Possible biological names infered from orthology : decapping mRNA 1A / Q9NPI6
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: B
Gene start: 30479535
Gene end: 30527063
  
Corresponding Affymetrix probe sets: 10413530 (MoGene1.0st)   1422131_at (Mouse Genome 430 2.0 Array)   1431933_a_at (Mouse Genome 430 2.0 Array)   1433606_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152897
Ensembl peptide - ENSMUSP00000153370
Ensembl peptide - ENSMUSP00000153074
Ensembl peptide - ENSMUSP00000022535
NCBI entrez gene - 75901     See in Manteia.
MGI - MGI:1923151
RefSeq - XM_006519655
RefSeq - XM_006519656
RefSeq - NM_133761
RefSeq Peptide - NP_598522
swissprot - Q91YD3
swissprot - A0A286YDC8
swissprot - A0A286YCN4
Ensembl - ENSMUSG00000021962
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dcp1aENSDARG00000100136Danio rerio
 ENSGALG00000041547Gallus gallus
 DCP1AENSG00000272886Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dcp1b / Q3U564 / mRNA-decapping enzyme 1B / Q8IZD4* / decapping mRNA 1B*ENSMUSG0000004147726


Protein motifs (from Interpro)
Interpro ID Name
 IPR010334  mRNA-decapping enzyme subunit 1
 IPR011993  PH-like domain superfamily
 IPR031953  mRNA-decapping enzyme, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway ISA
 biological_processGO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA IBA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISA
 biological_processGO:1903608 protein localization to cytoplasmic stress granule IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex ISA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IEA
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0008047 enzyme activator activity IEA
 molecular_functionGO:0008134 transcription factor binding ISA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019894 kinesin binding IEA
 molecular_functionGO:0030234 enzyme regulator activity IBA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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