| MP:0000351 | increased cell proliferation | "greater than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hrhr/Hrhr,Ptgs2tm1Unc/Ptgs2tm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SKH1
Allelic Composition: Hrhr/Hrhr,Ptgs1tm1Unc/Ptgs1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SKH1
|
| MP:0000352 | decreased cell proliferation | "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hrhr/Hrhr,Ptgs1tm1Unc/Ptgs1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SKH1
|
| MP:0000377 | abnormal hair follicle | "malformed invagination of the epidermis from which the hair shaft develops" [J:65031] |
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Allelic Composition: Dnmt3ltm1Bes/Dnmt3ltm1Bes
Genetic Background: involves: 129S6/SvEvTac
Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrtm1Cct/Hrtm1Cct,Tg(KRT14-Hr)551Cct/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
Allelic Composition: Hrrh-10J/Hrrh-10J
Genetic Background: C57BL/6J-Hrrh-10J/GrsrJ
|
| MP:0000385 | distended hair follicles | "follicles that have swollen or expanded from the skin" [J:53379] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
|
| MP:0000414 | alopecia | "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796] |
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Allelic Composition: Styxtm1.1Jedi/Styxtm1.1Jedi
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: C57BL/6)
Allelic Composition: Hrrh-bmh/Hrrh-bmh
Genetic Background: involves: C57BL/6JRj * CBA/JRj
Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: Hrtm1Cct/Hrtm1Cct
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrm1Enu/Hrm1Enu
Genetic Background: BALB/cJ-Hrm1Enu
Allelic Composition: Hrtm1Cct/Hrtm1Cct,Tg(KRT14-Hr)551Cct/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: Hrrh-8J/Hrrh-8J
Genetic Background: B10.D2/nSnJ-Hrrh-8J
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrHp/Hr+
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrM3Btlr/HrM3Btlr
Genetic Background: C57BL/6J-HrM3Btlr
Allelic Composition: Hrm4Btlr/Hrm4Btlr
Genetic Background: C57BL/6J-Hrm4Btlr
Allelic Composition: Hrm5Btlr/Hrm5Btlr
Genetic Background: C57BL/6J-Hrm5Btlr
|
| MP:0000416 | sparse fur | "fur that is significantly less dense" [J:46854] |
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Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
Allelic Composition: HrHp/Hr+
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrN/Hr+
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
|
| MP:0000417 | short hair | "reduced average length of the hairs" [J:64948] |
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Allelic Composition: HrHp/Hr+
Genetic Background: BALB/cJ-HrHp
|
| MP:0000425 | loss of cilia | "inability to retain the eyelashes " [J:45400] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1
|
| MP:0000427 | abnormal hair cycle | "aberrant growth or asynchronous timing of the hair growth " [J:65302] |
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Allelic Composition: Sox18tm1Koop/Sox18+
Genetic Background: B6.129-Sox18tm1Koop
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
|
| MP:0000495 | abnormal colon morphology | "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Musktm1.1Vwi/Musktm2Vwi
Genetic Background: Not Specified
|
| MP:0000511 | abnormal intestinal mucosa morphology | "structural or developmental anomalies of the mucous lining of the intestine; this consists of epithelium, lamina, propria, and a layer of smooth muscle cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Musktm1.1Vwi/Musktm2Vwi
Genetic Background: Not Specified
|
| MP:0000580 | deformed nails | "atypical shape or size of the nails" [J:45400] |
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Allelic Composition: Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Hrm1Enu/Hrm1Enu
Genetic Background: BALB/cJ-Hrm1Enu
Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
|
| MP:0000583 | long toenails | "increased length of the toenails" [J:65045] |
Show
Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrm1Btlr/Hrm1Btlr
Genetic Background: C57BL/6J-Hrm1Btlr
Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
Allelic Composition: Hrrh-10J/Hrrh-10J
Genetic Background: C57BL/6J-Hrrh-10J/GrsrJ
|
| MP:0000607 | abnormal hepatocyte morphology | "malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Ercc1tm1Dwm/Ercc1tm2Dwm,Hrhr/Hrhr,Tg(KRT5-cre)5132Jlj/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J * MF1
|
| MP:0000627 | abnormal mammary gland morphology | "malformation of the milk-secreting gland that lies within the breast; usually rudimentary in males" [J:70183] |
Show
Allelic Composition: Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0000629 | absent mammary gland | "missing milk-secreting glands of the breast" [J:18378] |
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Allelic Composition: Gtf2ird1tm1Lro/Gtf2ird1tm1Lro
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
|
| MP:0000647 | abnormal sebaceous gland morphology | "malformation of the holocrine glands of the dermis that secrete sebum into the hair follicles" [MGI:tc] |
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Allelic Composition: Braftm1Wds/Braftm1.1Wds,Raf1tm1Bacc/Raf1tm2Bacc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
|
| MP:0000649 | sebaceous gland atrophy | "wasting or decreased size of holocrine glands of the dermis that secrete sebum into the hair follicles" [J:65146] |
Show
Allelic Composition: Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0001191 | abnormal skin condition | "anomalous state of the skin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
Allelic Composition: HrTg5053Mm/HrTg5053Mm
Genetic Background: involves: C3H/He * C57BL/6J
Allelic Composition: HrN/Hrhr
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
|
| MP:0001195 | flaky skin | "shedding scales on the skin " [J:56641] |
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Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
|
| MP:0001196 | shiny skin | "skin with a glossy or glistening appearance" [J:56641] |
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Allelic Composition: HrN/Hr+
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
|
| MP:0001199 | thin skin | "reduced thickness of the outer protective layer of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471] |
Show
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrN/HrN
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
Allelic Composition: HrN/Hr+
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
|
| MP:0001200 | thick skin | "greater depth of skin " [J:47225] |
Show
Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrm2Btlr/Hrm2Btlr
Genetic Background: C57BL/6J-Hrm2Btlr
Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
Allelic Composition: HrTg5053Mm/HrTg5053Mm
Genetic Background: involves: C3H/He * C57BL/6J
Allelic Composition: Hrrh-10J/Hrrh-10J
Genetic Background: C57BL/6J-Hrrh-10J/GrsrJ
|
| MP:0001201 | translucent skin | "skin that is more transparent to light than normal " [J:15108] |
Show
Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
|
| MP:0001203 | skin irradiation sensitivity | "increased incidence of aberrant or damaged cells due to irradiation induced genotoxic damage" [J:65162] |
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Allelic Composition: Ercc1tm1Dwm/Ercc1tm2Dwm,Hrhr/Hrhr,Tg(KRT5-cre)5132Jlj/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J * MF1
|
| MP:0001204 | skin irradiation resistance | "decreased incidence of aberrant or damaged cells due to irradiation induced genotoxic damage" [J:65162] |
Show
Allelic Composition: Tyrc-112K/Tyrc-112K
Genetic Background: involves: 101/R1 * C3Hf/R1 * St.2A
|
| MP:0001210 | thick skin ridges | "long raised strips of skin, usually aligned to the proximal-distal axis" [J:51296] |
Show
Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
|
| MP:0001211 | wrinkled skin | "irregular folds and/or indentations on the skin" [J:19212] |
Show
Allelic Composition: Styxtm1.1Jedi/Styxtm1.1Jedi
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: C57BL/6)
Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: Hrtm1Cct/Hrtm1Cct
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrm1Btlr/Hrm1Btlr
Genetic Background: C57BL/6J-Hrm1Btlr
Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
Allelic Composition: Hrm2Btlr/Hrm2Btlr
Genetic Background: C57BL/6J-Hrm2Btlr
Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
Allelic Composition: HrTg5053Mm/HrTg5053Mm
Genetic Background: involves: C3H/He * C57BL/6J
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrHp/Hr+
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrN/HrN
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
Allelic Composition: Hrhr/Hrrh-2J
Genetic Background: involves: BALB/cBy * C57BL/6By * HRS/J
Allelic Composition: Hrrh-10J/Hrrh-10J
Genetic Background: C57BL/6J-Hrrh-10J/GrsrJ
Allelic Composition: Hrm5Btlr/Hrm5Btlr
Genetic Background: C57BL/6J-Hrm5Btlr
|
| MP:0001212 | skin lesions | "focal patches of inflammation on the skin" [J:30162] |
Show
Allelic Composition: HrTg5053Mm/HrTg5053Mm
Genetic Background: involves: C3H/He * C57BL/6J
|
| MP:0001214 | skin hyperplasia | "increased cell number in the skin; usually results in thick skin" [J:47225] |
Show
Allelic Composition: Hrtm1Cct/Hrtm1Cct
Genetic Background: involves: 129/Sv * C57BL/6
|
| MP:0001216 | abnormal epidermal layer morphology | "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Zeb2tm1.1Yhi/Zeb2tm1.1Yhi,Tg(Pax6-cre,GFP)1Pgr/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * FVB
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrHp/Hr+
Genetic Background: BALB/cJ-HrHp
|
| MP:0001219 | thickened epidermis | "increase in the width of the epidermal cell layer in the skin" [J:65146] |
Show
Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
|
| MP:0001222 | epidermal hyperplasia | "increase in size of the epidermis due to increase in epidermal cell number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146] |
Show
Allelic Composition: Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0001239 | abnormal granular layer morphology | "structural or developmental anomaly of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
|
| MP:0001240 | abnormal cornified layer morphology | "structural or developmental anomaly of the outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Hrm1Enu/Hrm1Enu
Genetic Background: BALB/cJ-Hrm1Enu
|
| MP:0001242 | hyperkeratosis | "increased depth of the corneal layer of the epidermis; thickening of the horny layer of the epidermis" [J:1133] |
Show
Allelic Composition: Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
|
| MP:0001243 | abnormal dermal layer morphology | "malformed or atypical condition of the dermal layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:56777] |
Show
Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0001245 | thick dermal layer | "increased depth of the dermis" [J:65033] |
Show
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0001247 | dermal cysts | "abnormal membranous sacs appearing in the dermis" [J:53379] |
Show
Allelic Composition: Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Hrrh-bmh/Hrrh-bmh
Genetic Background: involves: C57BL/6JRj * CBA/JRj
Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: Hrtm1Cct/Hrtm1Cct
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrm1Enu/Hrm1Enu
Genetic Background: BALB/cJ-Hrm1Enu
Allelic Composition: Hrrh-Chr/Hrrh-Chr
Genetic Background: Not Specified
Allelic Composition: Hrrh-Y/Hrrh-Y
Genetic Background: involves: B10.R109/Y * C57BL/10SnY
Allelic Composition: Hrrh-8J/Hrrh-8J
Genetic Background: B10.D2/nSnJ-Hrrh-8J
Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
|
| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
|
| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Col2a1M3J/Col2a1+
Genetic Background: B6(Cg)-Col2a1M3J/GrsrJ
|
| MP:0001274 | curly vibrissae | "whiskers twisted into coils or spirals" [J:47620] |
Show
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrN/Hr+
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
|
| MP:0001279 | wavy vibrissae | "whiskers having undulations or a sinusoidal shape" [J:65044] |
Show
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrHp/Hr+
Genetic Background: BALB/cJ-HrHp
|
| MP:0001280 | loss of vibrissae | "inability to retain the whiskers" [J:45400] |
Show
Allelic Composition: Zeb2tm1.1Yhi/Zeb2tm1.1Yhi,Tg(Pax6-cre,GFP)1Pgr/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * FVB
Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
|
| MP:0001282 | short vibrissae | "decreased length of the vibrissae" [J:30249] |
Show
Allelic Composition: HrN/HrN
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
Allelic Composition: HrN/Hr+
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
|
| MP:0001312 | abnormal cornea morphology | "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Gfertm1.1Crg/Gfertm1.1Crg,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129 * C57BL/6 * DBA
|
| MP:0001340 | abnormal eyelid morphology | "malformation of the skin folds covering the front of the eyeball" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1
|
| MP:0001345 | meibomian gland atrophy | "wasting of the sebaceous glands embedded in the tarsal plate of each eyelid resulting in reduced size" [J:65146] |
Show
Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
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| MP:0001382 | abnormal nursing | "females do not nurse pups or nurse pups infrequently" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
|
| MP:0001510 | abnormal coat appearance | "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
Allelic Composition: HrN/Hr+
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
Allelic Composition: HrN/Hrhr
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
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| MP:0001785 | edema | "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065] |
Show
Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1
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| MP:0001806 | decreased IgM | "less than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0001824 | abnormal thymic involution | "premature or late decline in thymic function normally associated with advancing age" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0001851 | eye inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the eye" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1
|
| MP:0001874 | acanthosis | "diffuse hyperplasia of the spinous layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hrm1Enu/Hrm1Enu
Genetic Background: BALB/cJ-Hrm1Enu
|
| MP:0001882 | abnormal lactation | "atypical production of milk from the mammary gland" [J:51296] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
Allelic Composition: HrN/HrN
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
|
| MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Hrrh-Y/Hrrh-Y
Genetic Background: involves: B10.R109/Y * C57BL/10SnY
|
| MP:0002026 | leukemia | "progressive proliferation of abnormal leukocytes in hematopoietic tissues, organs and blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18542] |
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Allelic Composition: Zap70m1Saka/Zap70m1Saka
Genetic Background: involves: BALB/c
|
| MP:0002051 | skin papilloma | "a circumscribed, benign epithelial tumor projecting from the surrounding surface" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr,Xpatm1Tnka/Xpatm1Tnka
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
|
| MP:0002060 | abnormal skin morphology | "malformation or atypical structure of the membranous protective covering of the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:56777] |
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Allelic Composition: Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: Hrtm1Cct/Hrtm1Cct
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrrh-Y/Hrrh-Y
Genetic Background: involves: B10.R109/Y * C57BL/10SnY
Allelic Composition: Hrtm1Cct/Hrtm1Cct,Tg(KRT14-Hr)551Cct/0
Genetic Background: involves: 129/Sv * C57BL/6 * SJL
|
| MP:0002073 | abnormal hair growth | "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: HrN/HrN
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
Allelic Composition: Hrrh-7J/Hrrh
Genetic Background: involves: C57BL/6J * HRS/J
Allelic Composition: Hrhr/Hrhr-3J
Genetic Background: involves: MRL/MpJ
Allelic Composition: Hrhr-2Pas/Hrhr-2Pas
Genetic Background: BALB/c
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: Hrhr/Hrhr,Ptgs2tm1Unc/Ptgs2tm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SKH1
Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr,Xpatm1Tnka/Xpatm1Tnka
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
|
| MP:0002098 | abnormal vibrissae morphology | "irregular or unusual structure, appearance, or alignment of the vibrissae" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrHp/Hr+
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrN/HrN
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
Allelic Composition: HrN/Hr+
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
|
| MP:0002346 | abnormal lymph node secondary follicle | "anomaly in the immunologically active area of the lymph node cortex " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology:ISBN 0-397-51047-0] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0002490 | abnormal circulating immunoglobulin concentration | "deviation from the normal levels of glycoproteins present in the blood and other tissue, often functioning as antibodies" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0002493 | increased IgG | "greater than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0002500 | granulomatous inflammation | "chronic inflammation resulting from the failure of the acute inflammatory response and persistance of the injurious agent; characterized by a central area of marcophages, often fused into giant cells, and surrounded by T cells " [Pathology:ISBN 0-397-51047-0, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Zeb2tm1.1Yhi/Zeb2tm1.1Yhi,Tg(Pax6-cre,GFP)1Pgr/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * FVB
|
| MP:0002656 | abnormal keratinocyte differentiation | "developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum
" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
|
| MP:0002743 | glomerulonephritis | "glomerular disease characterized by diffuse inflammatory reaction that is not the acute response to infection of the kidneys" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0003355 | reduced ovulation | "reduction in the frequency in which an ovum is released from a rupturing ovarian follicle" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Hrrh-Y/Hrrh-Y
Genetic Background: involves: B10.R109/Y * C57BL/10SnY
|
| MP:0003413 | hair follicle degeneration | "a retrogressive impairment of function or destruction of the hair follicle" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:94517] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrrh-Y/Hrrh-Y
Genetic Background: involves: B10.R109/Y * C57BL/10SnY
Allelic Composition: HrTg5053Mm/HrTg5053Mm
Genetic Background: involves: C3H/He * C57BL/6J
|
| MP:0003414 | epidermal cyst | "a cyst formed of a mass of epidermal cells which is present beneath the epidermis; the wall is lined with stratified squamous epithelium and exhibits increased/abnormal keratinization" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
Allelic Composition: HrTg5053Mm/HrTg5053Mm
Genetic Background: involves: C3H/He * C57BL/6J
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrHp/Hr+
Genetic Background: BALB/cJ-HrHp
|
| MP:0003448 | altered tumor morphology | "changes in the expected pathology for a given tumor type compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Ptger2tm1Brey/Ptger2tm1Brey
Genetic Background: involves: 129S6/SvEvTac * BALB/c
|
| MP:0003637 | cochlear ganglion hypoplasia | "reduced numbers of the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Musktm1.1Vwi/Musktm2Vwi
Genetic Background: Not Specified
|
| MP:0003644 | thymus atrophy | "wasting of the thymus resulting in reduced size " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: Hrrh/Hrrh
Genetic Background: RHJ/LeJ
|
| MP:0003710 | abnormal physiological neovascularization | "anomalies in the development of new blood vessels in restoration of blood circulation during the healing process " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1
|
| MP:0003721 | increased tumor growth/size | "greater than expected development of tumorous growth when compared to controls" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ptger2tm1Brey/Ptger2tm1Brey
Genetic Background: involves: 129S6/SvEvTac * BALB/c
|
| MP:0003809 | abnormal hair shaft morphology | "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
|
| MP:0003813 | abnormal dermal papilla | "abnormalities in this specialized group of mesenchymal cells necessary for initiation of follicle development" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
|
| MP:0003815 | nude | "having no hair at some time during or throughout lifespan, generally referring to primary genetic hairlessness" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Hrrh-Chr/Hrrh-Chr
Genetic Background: Not Specified
Allelic Composition: Hrrh-Y/Hrrh-Y
Genetic Background: involves: B10.R109/Y * C57BL/10SnY
Allelic Composition: Hrm1Btlr/Hrm1Btlr
Genetic Background: C57BL/6J-Hrm1Btlr
Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
Allelic Composition: Hrm2Btlr/Hrm2Btlr
Genetic Background: C57BL/6J-Hrm2Btlr
Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
Allelic Composition: HrN/HrN
Genetic Background: involves: ORNL:STOCK Aw/a Oca2p
Allelic Composition: Hrhr/Hrhr-3J
Genetic Background: involves: MRL/MpJ
Allelic Composition: Hrhr-2Pas/Hrhr-2Pas
Genetic Background: BALB/c
Allelic Composition: Hrrh-10J/Hrrh-10J
Genetic Background: C57BL/6J-Hrrh-10J/GrsrJ
|
| MP:0003865 | lymph node inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the lymph nodes" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0003992 | increased mortality induced by ionizing radiation | "greater sensitivity to doses of ionizing radiation that include ultraviolet light, X-rays, or gamma rays" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr,Xpatm1Tnka/Xpatm1Tnka
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
|
| MP:0004126 | thin hypodermis | "reduced thickness of the innermost and thickest layer of the skin composed of loose connective tissue containing adipoctyes" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0004207 | squamous cell carcinoma | "a carcinoma that arises from stratified squamous epithelium that occurs in sites where glandular or columnar epithelium is normally present, such as the skin, esophagus, lungs and cervix" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tyrc-112K/Tyrc-112K
Genetic Background: involves: 101/R1 * C3Hf/R1 * St.2A
|
| MP:0004396 | decreased cochlear inner hair cell number | "decreased number (or less than the expected single row) of the flask-shaped inner hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: RHJ/LeJ
|
| MP:0004402 | decreased cochlear outer hair cell number | "decreased number (or less than the expected 3 rows) of the columnar outer hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: RHJ/LeJ
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| MP:0004501 | increased incidence of UV-induced tumors | "higher than normal frequency of tumor incidence induced by exposure to ultraviolet light" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ercc1tm1Dwm/Ercc1tm2Dwm,Hrhr/Hrhr,Tg(KRT5-cre)5132Jlj/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J * MF1
Allelic Composition: Hrhr/Hrhr,Tg(KRT14-Ptgs2)1Sumf/0
Genetic Background: involves: C57BL/6 * DBA/2 * FVB/N * SKH1
Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr,Xpatm1Tnka/Xpatm1Tnka
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
|
| MP:0004504 | decreased incidence of UV-induced tumors | "lower than normal frequency of tumor incidence induced by exposure to ultraviolet light" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tyrc-112K/Tyrc-112K
Genetic Background: involves: 101/R1 * C3Hf/R1 * St.2A
Allelic Composition: Hrhr/Hrhr,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SKH1
Allelic Composition: Hrhr/Hrhr,Ptger2tm1Brey/Ptger2tm1Brey
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SKH1
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| MP:0004526 | absent cochlear hair cell stereocilia | "complete absence of the nonmotile, actin-filled specialized microvilli (stereocilia) which are normally arrayed on cochlear inner and outer hair cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: RHJ/LeJ
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| MP:0004813 | absent linear vestibular evoked potential | "absence of the biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal s head)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zap70m1Saka/Zap70m1Saka
Genetic Background: involves: BALB/c
|
| MP:0004956 | decreased thymus weight | "reduction in the average weight of the primary lymphoid organ that is required for maturation of T cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
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| MP:0005018 | decreased T cell number | "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Zap70m1Saka/Zap70m1Saka
Genetic Background: involves: BALB/c
|
| MP:0005081 | abnormal stratum reticulare morphology | "structural anomaly of the thicker, deeper layer of the dermis, containing blood and lymph vessles, nerves and nerve endings, and hair follicles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ighg1tm1.1Ksho/Ighg1tm1.1Ksho
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0005095 | decreased T cell proliferation | "reduced clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Zap70m1Saka/Zap70m1Saka
Genetic Background: involves: BALB/c
|
| MP:0005251 | blepharitis | "inflammation of the eyelids" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1
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| MP:0005252 | abnormal meibomian gland morphology | "structural anomaly of the sebaceous glands embedded in the tarsal plate of each eyelid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
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| MP:0005350 | increased susceptibility to autoimmune disorders | "greater likelihood that an organism will develop disease characterized by production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
|
| MP:0005421 | loose skin | "condition in which the skin hangs in folds" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hrrhsl/Hrrhsl
Genetic Background: involves: BALB/c
Allelic Composition: Hrm1Enu/Hrm1Enu
Genetic Background: BALB/cJ-Hrm1Enu
Allelic Composition: Hrm1Btlr/Hrm1Btlr
Genetic Background: C57BL/6J-Hrm1Btlr
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| MP:0005425 | increased macrophage count | "greater than the normal numbers of macrophages" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:73418] |
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Allelic Composition: Zap70m1Saka/Zap70m1Saka
Genetic Background: involves: BALB/c
|
| MP:0005501 | abnormal skin physiology | "atypical function of the membranous protective covering of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ptger2tm1Brey/Ptger2tm1Brey
Genetic Background: involves: 129S6/SvEvTac * BALB/c
Allelic Composition: Hrhr/Hrhr,Ptger2tm1Brey/Ptger2+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SKH1
|
| MP:0005515 | uveitis | "inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina)" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
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Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1
|
| MP:0006162 | thick eyelids | "increased width of the eyelid" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
|
| MP:0008507 | thin retinal ganglion layer | "reduced thickness of the innermost nuclear layer of the retina, which contains neurons that project axons through the optic nerve to the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: RHJ/LeJ
|
| MP:0008513 | thin retinal inner plexiform layer | "reduced thickness of the retinal cell layer where bipolar and amacrine cell axons synapse with ganglion cell dendrites" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: RHJ/LeJ
|
| MP:0009003 | abnormal vibrissa number | "any anomaly in the number of the stiff hairs projecting from the face around the nose of most mammals which act as touch receptors" [MESH:A13.950, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
Allelic Composition: HrHp/Hr+
Genetic Background: BALB/cJ-HrHp
Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
|
| MP:0009004 | progressive hair loss | "thinning of hair (coat) over time, usually in a defined pattern, until entirely gone with no recurrent growth" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
Allelic Composition: HrTg5053Mm/HrTg5053Mm
Genetic Background: involves: C3H/He * C57BL/6J
Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
Allelic Composition: HrM3Btlr/HrM3Btlr
Genetic Background: C57BL/6J-HrM3Btlr
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| MP:0009600 | hypergranulosis | "increased thickness of the granular layer of the epidermis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
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| MP:0009601 | epidermis stratum granulosum hyperplasia | "overdevelopment or increased size, usually due an increased number of cells, of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
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| MP:0009623 | enlarged inguinal lymph nodes | "increased size of the lymph nodes located in the groin area" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
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| MP:0009635 | enlarged popliteal lymph nodes | "increased size of the lymph nodes which drain the legs" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
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| MP:0009703 | decreased birth body size | "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ercc1tm1Dwm/Ercc1tm2Dwm,Hrhr/Hrhr,Tg(KRT5-cre)5132Jlj/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J * MF1
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| MP:0009704 | skin squamous cell carcinoma | "a skin carcinoma derived from stratified squamous epithelium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr,Xpatm1Tnka/Xpatm1Tnka
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
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| MP:0009722 | abnormal nipple development | "an anomaly in the differentiation of the apex of the mammary gland on the integument surface into which the lactiferous ducts open" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
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| MP:0009814 | increased prostaglandin level | "increase in the amount in the body of any of a class of mediators with effects of vasodilation, vasoconstriction, and smooth muscle stimulation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hrhr/Hrhr,Tg(KRT14-Ptgs2)1Sumf/0
Genetic Background: involves: C57BL/6 * DBA/2 * FVB/N * SKH1
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| MP:0009815 | decreased prostaglandin level | "reduction in the amount in the body of any of a class of mediators with effects of vasodilation, vasoconstriction, and smooth muscle stimulation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hrhr/Hrhr,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SKH1
Allelic Composition: Hrhr/Hrhr,Ptgs1tm1Unc/Ptgs1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SKH1
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| MP:0009931 | abnormal skin appearance | "skin that looks different from the usual state" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrrh-8J/Hrrh-8J
Genetic Background: B10.D2/nSnJ-Hrrh-8J
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| MP:0009935 | abnormal meibomian gland acinus morphology | "anomalies of the sac-like structures comprising the sebaceous glands located at the rim of the eyelids and responsible for producing sebum" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
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| MP:0010234 | abnormal vibrissa follicle morphology | "any structural anomaly of one of the tubular invaginations of the epidermis enclosing the hair roots and from which grow the vibrissae located on the muzzle and face of many species" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: HrHp/Hr+
Genetic Background: BALB/cJ-HrHp
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| MP:0010300 | increased skin tumor incidence | "greater than the expected number of neoplasms in the skin tissue usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr,Xpatm1Tnka/Xpatm1Tnka
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Allelic Composition: Hrhr/Hrhr,Xpatm1Tnka/Xpatm1Tnka
Genetic Background: involves: C57BL/6 * CBA
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| MP:0010680 | abnormal skin adnexa physiology | "any functional anomaly of the tissue or structures associated with or embedded in the skin such as hair and hair follicles, sweat glands, sebaceous glands and claws or nails" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrm4Btlr/Hrm4Btlr
Genetic Background: C57BL/6J-Hrm4Btlr
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| MP:0010682 | abnormal hair follicle infundibulum morphology | "any structural anomaly of the most proximal part of the hair follicle relative to the epidermis, extending from the sebaceous duct to the epidermal surface" [PMID:19211055] |
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Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
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| MP:0010683 | dilated hair follicle infundibulum | "the luminal space of the hair follicle infundibulum is increased in volume or area, sometimes with an increase of contained fluid or sebum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrrh-bmh/Hrrh-bmh
Genetic Background: involves: C57BL/6JRj * CBA/JRj
Allelic Composition: Hrrh-8J/Hrrh-8J
Genetic Background: B10.D2/nSnJ-Hrrh-8J
Allelic Composition: Hrrh-R/Hrrh-R
Genetic Background: involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El
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| MP:0010684 | abnormal hair follicle outer root sheath morphology | "any structural anomaly of the outermost layer of the hair follicle that merges proximally with the basal layer of the interfollicular epidermis and distally with the hair bulb" [PMID:19211055] |
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Allelic Composition: Hrrh-bmh/Hrrh-bmh
Genetic Background: involves: C57BL/6JRj * CBA/JRj
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| MP:0010685 | abnormal hair follicle inner root sheath morphology | "any structural anomaly of the multilayered tube composed of terminally differentiated hair follicle keratinocytes that is surrounded by the outer root sheath; the layers of the inner root sheath include the companion layer, Henle s layer, Huxley s layer and the inner root sheath cuticle" [PMID:19211055] |
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Allelic Composition: Hrrh-bmh/Hrrh-bmh
Genetic Background: involves: C57BL/6JRj * CBA/JRj
Allelic Composition: HrHp/HrHp
Genetic Background: BALB/cJ-HrHp
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| MP:0010687 | absent hair follicle dermal papilla | "absence of the mesodermal signalling center of the hair follicle consisting of closely packed specialized mesenchymal fibroblasts" [PMID:19211055] |
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Allelic Composition: Hrrh-8J/Hrrh-8J
Genetic Background: B10.D2/nSnJ-Hrrh-8J
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| MP:0010699 | dilated hair follicles | "the luminal space of the hair follicle is increased in volume or area, sometimes with an increase of contained fluid or sebum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
Allelic Composition: Hrrh-10J/Hrrh-10J
Genetic Background: C57BL/6J-Hrrh-10J/GrsrJ
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Ercc1tm1Dwm/Ercc1tm2Dwm,Hrhr/Hrhr,Tg(KRT5-cre)5132Jlj/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J * MF1
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| MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Hrrh-10J/Hrrh-10J
Genetic Background: C57BL/6J-Hrrh-10J/GrsrJ
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| MP:0011225 | lymph node medullary cord hyperplasia | "increase in the number of normal cells in normal arrangement in the lymph node medullary cords, resulting in a thickening or enlargement of the structure, caused by stimuli including increased physiological demand, inflammatory response, hormonal changes or hormonal dysfunctions, and/or compensation due to a pathological cause elsewhere" [ISBN:0-683-40008-8, MGI:csmith] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
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| MP:0012431 | increased lymphoma incidence | "greater than the expected number of neoplasms characterized by a proliferation of malignant lymphocytes in lymphoid tissue in a specific population in a given time period" [http://orcid.org/0000-0001-5208-3432, MGI:csmith] |
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Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Hrhr/Hrhr,Msh2tm1Htr/Msh2tm1Htr,Xpatm1Tnka/Xpatm1Tnka
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
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| MP:0012725 | small sebaceous gland | "decreased size of the sebum secreting glands of the hair shaft" [MGI:mnk] |
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Allelic Composition: Hrrh-Chr/Hrrh-Chr
Genetic Background: Not Specified
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| MP:0013379 | decreased sebocyte cell number | "fewer than expected number of the highly specialized, sebum-producing epithelial cells of the sebaceous glands that release their content by rupture of the cell membrane and cellular degradation" [MGI:anna, PMID:19944183] |
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Allelic Composition: Hrrh-Chr/Hrrh-Chr
Genetic Background: Not Specified
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| MP:0013390 | Meibomian gland cyst | "a non-malignant fluid-filled swelling (cyst) of the eyelid area due to non-infectious obstruction or malfunctioning of a Meibomian gland causing extravasation of lipid material in the eyelid soft tissues with focal secondary granulomatous inflammation" [MGI:Anna] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
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| MP:0013392 | Meibomian gland inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the meibum-secreting modified lobulated sebaceous glands located at the rim of the eyelids inside the tarsal plate; chronic Meibomian gland inflammation can lead to a lump in the eyelid known as a Meibomian gland cyst (aka chalazion)" [MGI:Anna] |
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Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1
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| MP:0013529 | decreased nipple number | "fewer than the expected number of structures located on the apex of the mammary gland on the integument surface into which the lactiferous ducts open; normal female mice have five pairs of mammary glands and nipples (males have no nipples); two pairs of nipples are situated in the abdomino-inguinal region (inguinal group) and three pairs in the ventral thoracic region (pectoral or thoracic group)" [http://www.informatics.jax.org/cookbook/figures/figure48.shtml, http://www.informatics.jax.org/cookbook/figures/figure50.shtml, MGI:Anna] |
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Allelic Composition: Hrba/Hrba
Genetic Background: Not Specified
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| MP:0013585 | thymus cortex atrophy | "acquired diminution of the outer part of a thymus lobule that surrounds the medulla and is composed of closely packed lymphocytes, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:Anna] |
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Allelic Composition: HrUSP/HrUSP
Genetic Background: either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2)
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| MP:0013745 | abnormal eyelid margin morphology | "any structural anomaly of the confluence of the mucosal surface of the conjunctiva, the edge of the orbicularis, and the cutaneous epithelium" [http://one.aao.org/bcscsnippetdetail.aspx?id=2b7328d7-5eb2-4df3-812a-031ff1c1f904, http://www.medilexicon.com/medicaldictionary.php?s=palpebral+margins, MGI:Anna] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
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| MP:0014082 | decreased small intestinal villus height | "decreased height of the tiny hair-like projections which protrude from the inside of the small intestine and contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; usually accompanied by crypt elongation or hyperplasia" [MGI:Anna, PMID:16679353] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: RHJ/LeJ
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| MP:0030031 | abnormal forehead morphology | "any structural anomaly of the part of the face above the eyes; in human anatomy, the forehead is the fore part of the head, an area of the head bounded by three features, two of the skull and one of the scalp; the top of the forehead is marked by the hairline, the edge of the area where hair on the scalp grows while the bottom of the forehead is marked by the supraorbital ridge, the bone feature of the skull above the eyes; the two sides of the forehead are marked by the temporal ridge, a bone feature that links the supraorbital ridge to the coronal suture line and beyond" [HP:0000290] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
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| MP:0030570 | abnormal piliary canal morphology | "any structural anomaly of the tubular connection that is found between the epidermal surface and the most distal part of the hair follicle inner root sheath and contains the hair shaft" [PMID:19211055, UBERON:0035610] |
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Allelic Composition: Hrrh/Hrrh
Genetic Background: Not Specified
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| MP:0030571 | dilated piliary canal | "stretched or widened aperture of the luminal space of the tubular connection that is found between the epidermal surface and the most distal part of the hair follicle inner root sheath and contains the hair shaft; the infundibulum is the opening of the hair canal to the skin surface" [MGI:anna, PMID:11171393] |
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Allelic Composition: Hrrh-bmh/Hrrh-bmh
Genetic Background: involves: C57BL/6JRj * CBA/JRj
Allelic Composition: Hrtm1Cct/Hrtm1Cct
Genetic Background: involves: 129/Sv * C57BL/6
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