ENSMUSG00000022641


Mus musculus

Features
Gene ID: ENSMUSG00000022641
  
Biological name :Bbx
  
Synonyms : Bbx / HMG box transcription factor BBX / Q8VBW5
  
Possible biological names infered from orthology : BBX, HMG-box containing / Q8WY36
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B5
Gene start: 50191844
Gene end: 50432390
  
Corresponding Affymetrix probe sets: 10439854 (MoGene1.0st)   1422741_a_at (Mouse Genome 430 2.0 Array)   1425835_a_at (Mouse Genome 430 2.0 Array)   1428796_at (Mouse Genome 430 2.0 Array)   1430820_a_at (Mouse Genome 430 2.0 Array)   1458602_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119238
Ensembl peptide - ENSMUSP00000110121
Ensembl peptide - ENSMUSP00000110132
Ensembl peptide - ENSMUSP00000066384
Ensembl peptide - ENSMUSP00000086821
Ensembl peptide - ENSMUSP00000086826
NCBI entrez gene - 70508     See in Manteia.
MGI - MGI:1917758
RefSeq - XM_017317130
RefSeq - NM_027444
RefSeq - XM_011246006
RefSeq - XM_011246007
RefSeq - XM_011246008
RefSeq - XM_011246009
RefSeq - XM_006522543
RefSeq - XM_006522544
RefSeq - XM_006522545
RefSeq - XM_006522546
RefSeq - XM_006522547
RefSeq - XM_006522548
RefSeq - XM_006522549
RefSeq - XM_006522553
RefSeq - XM_006522554
RefSeq - XM_006522555
RefSeq - XM_006522560
RefSeq - XM_006522561
RefSeq - XM_006522563
RefSeq - XM_011246005
RefSeq Peptide - NP_001334169
RefSeq Peptide - NP_081720
swissprot - Q8VBW5
swissprot - B8JK50
Ensembl - ENSMUSG00000022641
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bbxENSDARG00000012699Danio rerio
 BBXENSGALG00000015353Gallus gallus
 BBXENSG00000114439Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cic / Q924A2 / capicua transcriptional repressor / Q96RK0*ENSMUSG0000000544216


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR019102  HMG box transcription factor BBX, domain of unknown function DUF2028
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0060348 bone development IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
Show

Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: B6Dnk;B6Brd;B6N-Asxl1tm1a(EUCOMM)Wtsi Tyrc-Brd/WtsiH

Allelic Composition: Bbxtm1a(EUCOMM)Wtsi/Bbxtm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0000438 abnormal skull morphology "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: B6Dnk;B6Brd;B6N-Asxl1tm1a(EUCOMM)Wtsi Tyrc-Brd/WtsiH

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: B6Dnk;B6Brd;B6N-Asxl1tm1a(EUCOMM)Wtsi Tyrc-Brd/WtsiH

Allelic Composition: Bbxtm1a(EUCOMM)Wtsi/Bbxtm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: B6Dnk;B6Brd;B6N-Asxl1tm1a(EUCOMM)Wtsi Tyrc-Brd/WtsiH

 MP:0002100 abnormal tooth morphology "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: B6Dnk;B6Brd;B6N-Asxl1tm1a(EUCOMM)Wtsi Tyrc-Brd/WtsiH

Allelic Composition: Bbxtm1a(EUCOMM)Wtsi/Bbxtm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0002495 increased IgA "greater than normal immunoglobulin class A level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Bbxtm1a(EUCOMM)Wtsi/Bbxtm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0002834 decreased heart weight "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Bbxtm1a(EUCOMM)Wtsi/Bbxtm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: B6Dnk;B6Brd;B6N-Asxl1tm1a(EUCOMM)Wtsi Tyrc-Brd/WtsiH

Allelic Composition: Bbxtm1a(EUCOMM)Wtsi/Bbxtm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0004686 decreased length of long bones "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Bbxtm1a(EUCOMM)Wtsi/Bbxtm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0004991 decreased bone strength "reduced ability of bone to endure the application of force without yielding or breaking" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Bbxtm1a(EUCOMM)Wtsi/Bbxtm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: B6Dnk;B6Brd;B6N-Asxl1tm1a(EUCOMM)Wtsi Tyrc-Brd/WtsiH

Allelic Composition: Bbxtm1a(EUCOMM)Wtsi/Bbxtm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6 * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr