ENSMUSG00000022766
Mus musculus | |
Features
| Gene ID: | ENSMUSG00000022766 | | | | | Biological name : | Serpind1 | | | | | Synonyms : | P49182 / serine (or cysteine) peptidase inhibitor, clade D, member 1 / Serpind1 | | | | | Possible biological names infered from orthology : | P05546 / serpin family D member 1 | | | | | Species: | Mus musculus | | | | | Chr. number: | 16 | | Strand: | 1 | | Band: | A3 | | Gene start: | 17331371 | | Gene end: | 17343572 | | | | | Corresponding Affymetrix probe sets: | 10433988 (MoGene1.0st) 1418680_at (Mouse Genome 430 2.0 Array) | | | | | Cross references: | Ensembl peptide - ENSMUSP00000023450
NCBI entrez gene - 15160
See in Manteia.
MGI - MGI:96051
RefSeq - XM_006521796
RefSeq - NM_001331047
RefSeq - NM_008223
RefSeq Peptide - NP_032249
RefSeq Peptide - NP_001317976
swissprot - P49182
Ensembl - ENSMUSG00000022766
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See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed
Ortholog prediction (from Ensembl)
Paralog prediction (from Ensembl)
| Serpina3i / P01011* / SERPINA3* / serpin family A member 3* | ENSMUSG00000079014 | 27 | | Q03734 / Serpina3m / Serine protease inhibitor A3M / P01011* / SERPINA3* / serpin family A member 3* | ENSMUSG00000079012 | 27 | | Serpina3n / serine (or cysteine) peptidase inhibitor, clade A, member 3N / P01011* / SERPINA3* / serpin family A member 3* | ENSMUSG00000021091 | 27 | | Serpina3k / serine (or cysteine) peptidase inhibitor, clade A, member 3K / P01011* / SERPINA3* / serpin family A member 3* | ENSMUSG00000058207 | 27 | | Serpina3j / serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J / P01011* / SERPINA3* / serpin family A member 3* | ENSMUSG00000079013 | 26 | | Q80X76 / Serpina3f / Serine protease inhibitor A3F / P01011* / SERPINA3* / serpin family A member 3* | ENSMUSG00000066363 | 26 | | P29621 / Serpina3c / Serine protease inhibitor A3C / P01011* / SERPINA3* / serpin family A member 3* | ENSMUSG00000066361 | 26 | | Q8BYY9 / Serpina3b / serine (or cysteine) peptidase inhibitor, clade A, member 3B / P01011* / SERPINA3* / serpin family A member 3* | ENSMUSG00000066364 | 26 | | Q9D7D2 / Serpina9 / serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 / Q86WD7* / serpin family A member 9* | ENSMUSG00000058260 | 26 | | Q8R121 / Serpina10 / Protein Z-dependent protease inhibitor / Q9UK55* / serpin family A member 10* | ENSMUSG00000061947 | 26 | | Q00897 / Serpina1d / serine (or cysteine) peptidase inhibitor, clade A, member 1D / P01009* / SERPINA1* / serpin family A member 1* | ENSMUSG00000071177 | 26 | | Serpina1c / serine (or cysteine) peptidase inhibitor, clade A, member 1C / P01009* / SERPINA1* / serpin family A member 1* | ENSMUSG00000079015 | 26 | | Q6P4P1 / Serpina3a / serine (or cysteine) peptidase inhibitor, clade A, member 3A / P01011* / SERPINA3* / serpin family A member 3* | ENSMUSG00000041536 | 26 | | P07758 / Serpina1a / serine (or cysteine) peptidase inhibitor, clade A, member 1A / P01009* / SERPINA1* / serpin family A member 1* | ENSMUSG00000066366 | 25 | | Q00898 / Serpina1e / serine (or cysteine) peptidase inhibitor, clade A, member 1E / P01009* / SERPINA1* / serpin family A member 1* | ENSMUSG00000072849 | 25 | | P22599 / Serpina1b / serine (or cysteine) preptidase inhibitor, clade A, member 1B / P01009* / SERPINA1* / serpin family A member 1* | ENSMUSG00000071178 | 25 | | P70458 / Serpina5 / serine (or cysteine) peptidase inhibitor, clade A, member 5 / P05154* / serpin family A member 5* | ENSMUSG00000041550 | 24 | | Serpina11 / serpin family A member 11 / Q86U17* | ENSMUSG00000063232 | 24 | | Q06770 / Serpina6 / serine (or cysteine) peptidase inhibitor, clade A, member 6 / P08185* / serpin family A member 6* | ENSMUSG00000060807 | 24 | | Q7TMF5 / Serpina12 / Serpin A12 / Q8IW75* / serpin family A member 12* | ENSMUSG00000041567 | 24 |
Protein motifs (from Interpro)
Gene Ontology (GO)
Pathways (from Reactome)
Phenotype (from MGI, Zfin or HPO)
| MP:0003674 | oxidative stress | "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Serpind1tm1Moto/Serpind1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
| | MP:0004883 | abnormal blood vessel healing | "anomaly in the repair process of blood vessels after injury" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Serpind1tm1Moto/Serpind1+
Genetic Background: B6.Cg-Serpind1tm1Moto
| | MP:0005048 | thrombosis | "formation within a tissue or the vascular lumen of a thrombus, an aggregation of coagulated blood containing platelets, fibrin, and entrapped cellular elements " [Pathology:ISBN 0-397-51047-0, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: PhexHyp-Duk/Phex+
Genetic Background: involves: BALB/cAnBomUrd
Allelic Composition: Serpind1tm1Moto/Serpind1+
Genetic Background: B6.Cg-Serpind1tm1Moto
| | MP:0005338 | atherosclerotic lesions | "thickening and loss of elasticity of arterial walls, involving lipid deposition and thickening of intimal layers within arteries" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Serpind1tm1Moto/Serpind1+
Genetic Background: B6.Cg-Serpind1tm1Moto
| | MP:0005489 | vascular smooth muscle cell hyperplasia | "increased numbers of smooth muscle cells in the vascular wall" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:48446] |
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Allelic Composition: Serpind1tm1Moto/Serpind1+
Genetic Background: B6.Cg-Serpind1tm1Moto
| | MP:0009548 | abnormal platelet aggregation | "any functional anomaly in the adhesion of one platelet to one or more other platelets via adhesion molecules" [GO:0070527] |
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Allelic Composition: Serpind1tm1Moto/Serpind1+
Genetic Background: B6.Cg-Serpind1tm1Moto
| | MP:0011097 | complete embryonic lethality before turning of embryo | "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith] |
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Allelic Composition: Gnetm1Mhzg/Gnetm1Mhzg
Genetic Background: involves: C57BL/6J
| | MP:0011477 | abnormal urine nucleoside level | "any change in the urinary level of glycosylamines consisting of a nucleobase bound to a ribose or deoxyribose sugar via a beta-glycosidic linkage, including cytidine, uridine, adenosine, guanosine, thymidine and inosine and deoxynucleosides" [MGI:csmith] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Serpind1tm1Moto/Serpind1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
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Interacting proteins (from Reactome)
| ENSMUSG00000027249 | F2 / P19221 / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain / P00734* / coagulation factor II, thrombin* | / reaction / complex |
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