ENSMUSG00000022884


Mus musculus

Features
Gene ID: ENSMUSG00000022884
  
Biological name :Eif4a2
  
Synonyms : Eif4a2 / Mus musculus eukaryotic translation initiation factor 4A2 (Eif4a2), transcript variant 5, mRNA. / P10630
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: B1
Gene start: 23107444
Gene end: 23114136
  
Corresponding Affymetrix probe sets: 10434733 (MoGene1.0st)   10434741 (MoGene1.0st)   10434743 (MoGene1.0st)   10434745 (MoGene1.0st)   1450934_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121745
Ensembl peptide - ENSMUSP00000118141
Ensembl peptide - ENSMUSP00000127030
Ensembl peptide - ENSMUSP00000140809
Ensembl peptide - ENSMUSP00000023599
Ensembl peptide - ENSMUSP00000090876
Ensembl peptide - ENSMUSP00000110998
Ensembl peptide - ENSMUSP00000115649
NCBI entrez gene - 13682     See in Manteia.
MGI - MGI:106906
RefSeq - XM_017316873
RefSeq - NM_001123037
RefSeq - NM_001123038
RefSeq - NM_001347179
RefSeq - NM_013506
RefSeq - XM_006521783
RefSeq - XM_006521784
RefSeq - XM_006521785
RefSeq Peptide - NP_001116510
RefSeq Peptide - NP_001334108
RefSeq Peptide - NP_038534
RefSeq Peptide - NP_001116509
swissprot - D6RJ60
swissprot - P10630
swissprot - Q52KC1
swissprot - Q8BTU6
swissprot - D6RJ11
swissprot - E9Q561
Ensembl - ENSMUSG00000022884
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif4a2ENSDARG00000016477Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Eif4a1 / P60843 / Eukaryotic initiation factor 4A-I / P60842* / eukaryotic translation initiation factor 4A1*ENSMUSG0000005979690
Eif4a3 / Q91VC3 / Eukaryotic initiation factor 4A-III Eukaryotic initiation factor 4A-III, N-terminally processed / P38919* / eukaryotic translation initiation factor 4A3*ENSMUSG0000002558067
Gm8994 / EIF4A3* / P38919* / eukaryotic translation initiation factor 4A3*ENSMUSG0000009497366
Gm5580 / EIF4A3* / P38919* / eukaryotic translation initiation factor 4A3*ENSMUSG0000010790666


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR037583  Eukaryotic initiation factor 4A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:1900260 negative regulation of RNA-directed 5"-3" RNA polymerase activity ISO
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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