ENSMUSG00000023064


Mus musculus

Features
Gene ID: ENSMUSG00000023064
  
Biological name :Sncg
  
Synonyms : Q9Z0F7 / Sncg / synuclein, gamma
  
Possible biological names infered from orthology : O76070
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: B
Gene start: 34370274
Gene end: 34374789
  
Corresponding Affymetrix probe sets: 10418921 (MoGene1.0st)   1417788_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023826
NCBI entrez gene - 20618     See in Manteia.
MGI - MGI:1298397
RefSeq - NM_011430
RefSeq Peptide - NP_035560
swissprot - Q5GQ64
swissprot - Q9Z0F7
Ensembl - ENSMUSG00000023064
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sncgaENSDARG00000034423Danio rerio
 sncgbENSDARG00000109715Danio rerio
 SNCGENSGALG00000002015Gallus gallus
 SNCGENSG00000173267Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Snca / O55042 / Alpha-synuclein / P37840* / synuclein alpha*ENSMUSG0000002588959
Sncb / Q91ZZ3 / Beta-synuclein / Q16143* / synuclein beta*ENSMUSG0000003489154


Protein motifs (from Interpro)
Interpro ID Name
 IPR001058  Synuclein
 IPR002462  Gamma-synuclein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007268 chemical synaptic transmission IGI
 biological_processGO:0008344 adult locomotory behavior IGI
 biological_processGO:0009306 protein secretion IDA
 biological_processGO:0014059 regulation of dopamine secretion IGI
 biological_processGO:0046928 regulation of neurotransmitter secretion IGI
 biological_processGO:0050808 synapse organization IGI
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011448 decreased dopaminergic neuron number "fewer than normal numbers of the neurons that utilize dopamine as a neurotransmitter" [MGI:smb]
Show

Allelic Composition: Hoxb8tm1Omm/Hoxb8+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Sncgtm1Vlb/Sncgtm1Vlb
Genetic Background: B6.129-Sncatm1Rosl Sncgtm1Vlb

 MP:0011452 decreased susceptibility to dopaminergic neuron neurotoxicity "less than normal amount of dopaminergic neuronal cell death following exposure to a neurotoxic compound, such as MPTP-induced cell death occurring through interference in mitochondrial metabolism" [MGI:csmith]
Show

Allelic Composition: Hoxb8tm1Omm/Hoxb8+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Sncatm1Rosl/Sncatm1Rosl,Sncgtm1Vlb/Sncgtm1Vlb
Genetic Background: B6.129-Sncatm1Rosl Sncgtm1Vlb

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr