| MP:0000598 | abnormal liver morphology | "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170] |
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Allelic Composition: Cyp1a2/Cyp1a1tm1.1Bra/Cyp1a2/Cyp1a1tm1.1Bra
Genetic Background: B6.129-Cyp1a2/Cyp1a1tm1.1Bra
|
| MP:0000607 | abnormal hepatocyte morphology | "malformation of the main structural component of the liver; these are specialized epithelial cells normally organize into interconnected plates called lobules" [J:23170, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0001182 | lung hemorrhage | "bleeding in the respiratory organs" [J:66345] |
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Allelic Composition: Cyp1a2/Cyp1a1tm1.1Bra/Cyp1a2/Cyp1a1tm1.1Bra
Genetic Background: B6.129-Cyp1a2/Cyp1a1tm1.1Bra
|
| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT)AHlps/0,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0001263 | weight loss | "progressive reduction of body weight below normal average for age" [J:45400] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
Allelic Composition: Muttm1.1Mrb/Muttm1.1Mrb
Genetic Background: involves: C57BL/6
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT)AHlps/0,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
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Allelic Composition: Epha4tm5Kln/Epha4tm5Kln
Genetic Background: involves: 129 * C57BL/6
|
| MP:0001429 | dehydration | "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053] |
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Allelic Composition: Cyp1a2/Cyp1a1tm1.1Bra/Cyp1a2/Cyp1a1tm1.1Bra
Genetic Background: B6.129-Cyp1a2/Cyp1a1tm1.1Bra
|
| MP:0001436 | abnormal suckling behavior | "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461] |
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Allelic Composition: Epha4tm5Kln/Epha4tm5Kln
Genetic Background: involves: 129 * C57BL/6
|
| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
Allelic Composition: Muttm1.1Mrb/Muttm1.1Mrb
Genetic Background: involves: C57BL/6
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0001764 | abnormal homeostasis | "anomaly in the state of equilibrium in the body with respect to various functions and to chemical composition of the fluids and tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Vps52tm1.1Kab/Vps52tm1.2Kab,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: C57BL * C57BL/6 * CBA * DBA
Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT)AHlps/0,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0001859 | kidney inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0001944 | abnormal pancreas morphology | "malformation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0001954 | respiratory distress | "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
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Allelic Composition: Epha4tm5Kln/Epha4tm5Kln
Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd
|
| MP:0002135 | abnormal kidney morphology | "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Degs1Gt(OST368559)Lex/Degs1+
Genetic Background: involves: 129S5/SvEvBrd
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0002136 | abnormal kidney physiology | "altered ability or inability to excrete urine, not due to anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0002152 | abnormal brain morphology | "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk] |
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Allelic Composition: Cyp1a2/Cyp1a1tm1.1Bra/Cyp1a2/Cyp1a1tm1.1Bra
Genetic Background: B6.129-Cyp1a2/Cyp1a1tm1.1Bra
Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0002176 | high brain weight | "greater than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0002628 | fatty liver | "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0002703 | abnormal renal tubules | "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0002981 | increased liver weight | "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT)AHlps/0,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0003017 | decreased circulating bicarbonate level | "reduced concentration of inorganic salts that contain the -HCO3 radical in the circulation, which are an important factor in regulating the pH of the blood " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0003019 | increased circulating chloride level | "elevated concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0003030 | acidemia | "increased concentration of H-ion in the blood or a fall below normal in pH" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0003031 | acidosis | "a pathological state characterized by an increase in the hydrogen ion concentration of arterial blood; caused by an decrease in the concentration of alkaline compounds, or by a increase in the concentration of acidic compounds or carbon dioxide to the body fluids" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Vps52tm1.1Kab/Vps52tm1.2Kab,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: C57BL * C57BL/6 * CBA * DBA
Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT)AHlps/0,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Muttm1.1Mrb/Muttm1.1Mrb
Genetic Background: involves: C57BL/6
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0003620 | decreased urine output | "decreased volume of urine produced and excreted" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0003674 | oxidative stress | "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0003917 | increased kidney weight | "greater heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission] |
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Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT)AHlps/0,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0003979 | increased circulating carnitine level | "greater than normal blood concentration of this quaternary ammonium amino acid derivative involved in transport of fatty acids across the mitochondrial membrane" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Epha4tm5Kln/Epha4tm5Kln
Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT)AHlps/0,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Muttm1.1Mrb/Muttm1.1Mrb
Genetic Background: involves: C57BL/6
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0004756 | abnormal proximal convoluted tubule morphology | "any structural anomaly of the convoluted portion of the duct system of the nephron that extends from the renal glomeurlar capsule in the kidney cortex into the kidney medulla where it joins the loop of Henle; fluid entering the proximal convoluted tubule is reabsorbed into the peritubular capillaries, including approximately two-thirds of the filtered salt and water and all filtered organic solutes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0005217 | abnormal pancreatic beta cell morphology | "malformation of the cells of the pancreas that secrete insulin" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0005220 | abnormal exocrine pancreas morphology | "malformation of the acinar gland portion of the pancreas that secretes digestive enzymes " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0005266 | abnormal metabolism | "anomalous chemical and physical changes occurring in tissue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT)AHlps/0,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0005280 | abnormal fatty acid level | "anomalous concentration of organic, monobasic acids derived from hydrocarbons and which are complexed with serum albumin for transport; they are saturated and unsaturated" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Muttm1.1Mrb/Muttm1.1Mrb
Genetic Background: involves: C57BL/6
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0005309 | increased circulating ammonia level | "significantly elevated levels of ammonia or its compounds in blood; often associated with liver failure and hepatic encephalopathy " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83263] |
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Allelic Composition: Muttm1.1Mrb/Muttm1.1Mrb
Genetic Background: involves: C57BL/6
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0005311 | abnormal circulating amino acid level | "aberrant concentration in the blood of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:83263] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
Allelic Composition: Muttm1.1Mrb/Muttm1.1Mrb
Genetic Background: involves: C57BL/6
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0005441 | hypercalciuria | "excretion of abnormally large amounts of calcium in the urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:86949] |
Show
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0005528 | decreased glomerular filtration rate | "less than the normal volume of water filtered out of the plasma through glomerular capillary walls into thte Bowman s capsule per unit time" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0005553 | increased circulating creatinine level | "greater than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0005565 | increased blood urea nitrogen level | "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0005619 | increased potassium excretion | "greater than the normal amount of this alkaline metallic element, the most abundant intracellular ion, voided by the kidneys" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0006316 | increased urine sodium level | "higher than normal concentration of sodium in the urine" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0008986 | abnormal liver parenchyma morphology | "any structural anomaly of the functional units of the liver including the lobules" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Epha4tm5Kln/Epha4tm5Kln
Genetic Background: involves: 129 * C57BL/6
|
| MP:0009546 | absent gastric milk in neonates | "failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Epha4tm5Kln/Epha4tm5Kln
Genetic Background: involves: 129 * C57BL/6
|
| MP:0009642 | abnormal blood homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0010028 | aciduria | "excretion of an acid urine" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Epha4tm5Kln/Epha4tm5Kln
Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT)AHlps/0,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Muttm1.1Mrb/Muttm1.1Mrb
Genetic Background: involves: C57BL/6
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0010107 | abnormal renal reabsorption | "any anomaly in the two-step process beginning with the active or passive extraction of substances (such as water, glucose, oligopeptides, amino acids, sodium (Na+) and other ions) from the renal tubule fluid into the renal interstitium, and the subsequent transport of these substances out of the renal interstitium back into the bloodstream; reabsorption begins in the proximal convoluted tubules and continues in the loop of Henle, distal convoluted tubules, and collecting tubules" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0010955 | abnormal respiratory electron transport chain | "anomaly in the process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient" [GO:0022904] |
Show
Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
|
| MP:0010958 | abnormal tricarboxylic acid cycle | "any anomaly in the universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes; the acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle" [GO:0006099] |
Show
Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
|
| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
Show
Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
Show
Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
|
| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
Show
Allelic Composition: Epha4tm5Kln/Epha4tm5Kln
Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Muttm1Pai/Muttm1Pai,Tg(MUT*R403X)#Hlps/0
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
Show
Allelic Composition: Muttm1Cpv/Muttm1Cpv
Genetic Background: Not Specified
|
| MP:0011405 | tubulointerstitial nephritis | "diffuse or local inflammation and edema of the interstitial tissue of the kidney, including the renal tubules; usually secondary to drug sensitization, systemic infection, graft rejection, or autoimmune disease" [MGI:anna] |
Show
Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0011435 | increased urine magnesium level | "higher than normal amount of magnesium in the urine" [MGI:anna] |
Show
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0011459 | increased urine chloride ion level | "abnormally large amounts of chloride ion in the urine" [MGI:csmith] |
Show
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0011635 | abnormal mitochondrial crista morphology | "Any of the inward folds of the mitochondrial inner membrane; crista number, extent, and shape differ in mitochondria from different tissues and organisms; crista appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found; the shape can vary with the respiratory state of the mitochondria" [GO:0030061] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0011637 | abnormal mitochondrial matrix morphology | "any structural anomaly of the gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion, and contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation" [GO:0005759] |
Show
Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
|
| MP:0012230 | abnormal sphingolipid level | |
Show
Allelic Composition: Muttm1Pai/Muttm1.1Mrb
Genetic Background: involves: 129S1/Sv * C57BL/6
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| MP:0012551 | metabolic acidosis | "decreased pH and bicarbonate concentration in tissues and/or body fluids caused when the body produces too much acid or when the kidneys are not removing enough acid from the body, as in diarrhea or in kidney disease" [ISBN:0-683-40008-8] |
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Allelic Composition: Muttm1Cpv/Muttm1Cpv,Tg(Alb-Mut)#Cpv/0
Genetic Background: involves: C57BL/6
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