ENSMUSG00000024037


Mus musculus

Features
Gene ID: ENSMUSG00000024037
  
Biological name :Wdr4
  
Synonyms : Wdr4 / WD repeat domain 4
  
Possible biological names infered from orthology : P57081
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: B1
Gene start: 31494323
Gene end: 31519974
  
Corresponding Affymetrix probe sets: 10449699 (MoGene1.0st)   1423138_at (Mouse Genome 430 2.0 Array)   1423139_at (Mouse Genome 430 2.0 Array)   1434522_at (Mouse Genome 430 2.0 Array)   1445109_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127617
Ensembl peptide - ENSMUSP00000127073
Ensembl peptide - ENSMUSP00000129736
Ensembl peptide - ENSMUSP00000132290
Ensembl peptide - ENSMUSP00000125954
Ensembl peptide - ENSMUSP00000126061
NCBI entrez gene - 57773     See in Manteia.
MGI - MGI:1889002
RefSeq - XM_011246553
RefSeq - XM_006524715
RefSeq - XM_006524716
RefSeq - XM_006524719
RefSeq - XM_006524720
RefSeq - XM_006524723
RefSeq - XM_006524724
RefSeq - XM_006524725
RefSeq - NM_021322
RefSeq Peptide - NP_067297
swissprot - F6VLT8
swissprot - F6YNC4
swissprot - E9Q1L4
swissprot - E9Q1H7
swissprot - E9Q156
swissprot - F7CM37
Ensembl - ENSMUSG00000024037
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wdr4ENSDARG00000090581Danio rerio
 WDR4ENSGALG00000016187Gallus gallus
 WDR4ENSG00000160193Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011044  Quinoprotein amine dehydrogenase, beta chain-like
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR028884  tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006400 tRNA modification IEA
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0030488 tRNA methylation IEA
 biological_processGO:0036265 RNA (guanine-N7)-methylation IEA
 biological_processGO:0106004 tRNA (guanine-N7)-methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043527 tRNA methyltransferase complex IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008176 tRNA (guanine-N7-)-methyltransferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000913 abnormal brain development "malformed or incomplete differentiation of the brain" [MGI:cls, J:49840]
Show

Allelic Composition: PrkdcM8Btlr/Prkdc+
Genetic Background: C57BL/6J-PrkdcM8Btlr

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: PrkdcM8Btlr/Prkdc+
Genetic Background: C57BL/6J-PrkdcM8Btlr

 MP:0008932 abnormal embryonic tissue physiology "any functional anomaly in any of the tissues of the embryo proper" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: PrkdcM8Btlr/Prkdc+
Genetic Background: C57BL/6J-PrkdcM8Btlr

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: PrkdcM8Btlr/Prkdc+
Genetic Background: C57BL/6J-PrkdcM8Btlr

 MP:0013504 increased embryonic tissue cell apoptosis "increase in the timing or the number of cells in embryonic tissue undergoing programmed cell death" [MGI:csmith]
Show

Allelic Composition: PrkdcM8Btlr/Prkdc+
Genetic Background: C57BL/6J-PrkdcM8Btlr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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