ENSG00000160193


Homo sapiens

Features
Gene ID: ENSG00000160193
  
Biological name :WDR4
  
Synonyms : P57081 / WDR4 / WD repeat domain 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q22.3
Gene start: 42843094
Gene end: 42879568
  
Corresponding Affymetrix probe sets: 221632_s_at (Human Genome U133 Plus 2.0 Array)   226882_x_at (Human Genome U133 Plus 2.0 Array)   241937_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328671
Ensembl peptide - ENSP00000381266
NCBI entrez gene - 10785     See in Manteia.
OMIM - 605924
RefSeq - NM_001260477
RefSeq - NM_018669
RefSeq - NM_033661
RefSeq - XM_017028264
RefSeq - NM_001260474
RefSeq - NM_001260475
RefSeq - NM_001260476
RefSeq - XM_011529433
RefSeq - XM_017028262
RefSeq - XM_017028263
RefSeq Peptide - NP_001247403
RefSeq Peptide - NP_387510
RefSeq Peptide - NP_001247406
RefSeq Peptide - NP_061139
RefSeq Peptide - NP_001247404
RefSeq Peptide - NP_001247405
swissprot - P57081
Ensembl - ENSG00000160193
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wdr4ENSDARG00000090581Danio rerio
 WDR4ENSGALG00000016187Gallus gallus
 Wdr4ENSMUSG00000024037Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR028884  tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006400 tRNA modification IDA
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0036265 RNA (guanine-N7)-methylation IEA
 biological_processGO:0106004 tRNA (guanine-N7)-methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm HDA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0043527 tRNA methyltransferase complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008176 tRNA (guanine-N7-)-methyltransferase activity IDA


Pathways (from Reactome)
Pathway description
tRNA modification in the nucleus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000037897 METTL1 / Q9UBP6 / methyltransferase like 1  / complex






 

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