ENSMUSG00000024155


Mus musculus

Features
Gene ID: ENSMUSG00000024155
  
Biological name :Meiob
  
Synonyms : Meiob / Meiosis-specific with OB domain-containing protein / Q9D513
  
Possible biological names infered from orthology : meiosis specific with OB domains / Q8N635
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A3.3
Gene start: 24804382
Gene end: 24839787
  
Corresponding Affymetrix probe sets: 10442606 (MoGene1.0st)   1431648_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024972
NCBI entrez gene - 75178     See in Manteia.
MGI - MGI:1922428
RefSeq - XM_017317702
RefSeq - NM_029197
RefSeq - XM_006525048
RefSeq - XM_006525052
RefSeq - XM_006525045
RefSeq - XM_006525047
RefSeq Peptide - NP_083473
swissprot - Q9D513
Ensembl - ENSMUSG00000024155
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 meiobENSDARG00000062442Danio rerio
 MEIOBENSGALG00000005411Gallus gallus
 MEIOBENSG00000162039Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR012340  Nucleic acid-binding, OB-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000712 resolution of meiotic recombination intermediates IMP
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0007129 synapsis IMP
 biological_processGO:0007140 male meiotic nuclear division IEP
 biological_processGO:0007141 male meiosis I IMP
 biological_processGO:0007144 female meiosis I IMP
 biological_processGO:0009566 fertilization IMP
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IMP
 molecular_functionGO:0003697 single-stranded DNA binding IDA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008310 single-stranded DNA 3"-5" exodeoxyribonuclease activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0001930 abnormal meiosis "malfunction in the process of nuclear division that results in gametes with one half the normal number of the original cell" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0004805 absent oocytes "absence of mature germ cells in the female" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0005431 oocyte depletion "reduced numbers or absence of germ cells in the female" [llw2:Linda Washburn , Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0010948 abnormal double-strand DNA break repair "any annomaly in the process of repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix" [GO:0006302]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

 MP:0013507 increased ovary apotosis "increase in the timing or the number of ovary cells undergoing programmed cell death" [MGI:csmith]
Show

Allelic Composition: Ap3d1mh-4J/Ap3d1mh-4J
Genetic Background: involves: 129P2/OlaHsd * BALB/cByJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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