| MP:0002118 | abnormal lipid homeostasis | "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0004889 | increased energy expenditure | "increase in the number of calories used per unit time or decrease in weight gain for a given amount of food eaten" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0005266 | abnormal metabolism | "anomalous chemical and physical changes occurring in tissue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0005289 | increased oxygen consumption | "greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0005336 | abnormal inguinal fat pad | "malformed or aberrant size of the encapsulated adipose tissue found in the groin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:84541] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0005533 | increased body temperature | "greater than the level of heat natural to a living being" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0005670 | abnormal white fat physiology | "functional aberration in the connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0006036 | abnormal mitochondrial physiology | |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0008034 | enhanced lipolysis | "increase in the rate of the hydrolysis of fat into free fatty acids " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0009116 | abnormal brown fat cell morphology | "any structural anomaly of cells from the thermogenic form of adipose tissue found in newborns of many species, including humans, and in hibernating mammals; brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation; brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria" [CL:0000449, GO:0050873, MESH:A.10.165.114.322] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0009117 | abnormal white fat cell morphology | "any structural anomaly of fat cells with light coloration and few mitochondria; these contain a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole" [MESH:A11.329.114.500] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0009125 | decreased brown fat cell lipid droplet size | "reduction in the size of the multiple small droplets of triglycerides found in brown adipocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0014171 | increased fatty acid oxidation | "increased rate or incidence of the process of removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen" [GO:0019395] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0020426 | abnormal beige fat cell physiology | "any functional anomaly of fat cells that are beige in color, thermogenic, and which differentiates in white fat tissue from a Myf5-negative progenitor" [CL_0001070, PMID:22796012, PMID:23603813, PMID:24575370] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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| MP:0020523 | decreased susceptibility to induced hypothermia | "smaller than expected drop in body temperature in response to treatment (cold-exposure, dietary restriction, ethanol treatment, etc..) designed to induce hypothermia" [MGI:mperry, PMID:24531262] |
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Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J
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