| MP:0000010 | abnormal abdominal fat pads | "malformed or aberrant size of the encapsulated adipose tissue in the abdomen" [J:65146] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0000026 | abnormal inner ear morphology | "malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: involves: C57BL/6J
|
| MP:0000031 | abnormal cochlea morphology | "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1Tw
Genetic Background: B6.Cg-Zeb1tm1.1Ajg/Zeb1Tw
|
| MP:0000037 | abnormal lateral semicircular canal | "anomaly of the lateral long bony tube of the labyrinth that is involved in the sense of balance " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm2Yhi/Zeb1Tw
Genetic Background: B6.Cg-Zeb1tm2Yhi/Zeb1Tw
|
| MP:0000088 | short mandible | "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000091 | short premaxilla | "reduced length of the anterior and interior portion of the maxilla" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000097 | short maxilla | "reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000100 | abnormal ethmoidal bone morphology | "defect in the midline facial bone that encloses the nasal cavity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
|
| MP:0000106 | abnormal basisphenoid bone morphology | "malformed base of the sphenoid bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0000108 | midline facial cleft | "incomplete merging or fusion of the tissues normally uniting to form the face" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.2Yhi/Zeb2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
|
| MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm1.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg
Allelic Composition: Zeb1tm1.1Ajg/Zeb1Tw
Genetic Background: B6.Cg-Zeb1tm1.1Ajg/Zeb1Tw
|
| MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000154 | rib fusion | "appearance of one or more ribs as a single structure" [J:62022, J:62023] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0000157 | abnormal sternum morphology | "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000159 | abnormal xiphoid process | "malformed posterior tip of the sternum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:42932] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0000221 | decreased WBC count | "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
|
| MP:0000222 | decreased neutrophil count | "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
|
| MP:0000371 | diluted coat color | "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: involves: C57BL/6J
|
| MP:0000416 | sparse fur | "fur that is significantly less dense" [J:46854] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: involves: C57BL/6J
|
| MP:0000454 | abnormal jaw morphology | "malformation of the bony framework of the mouth where the teeth are held" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000460 | mandible hypoplasia | "arrested growth or atrophy of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000547 | short limbs | "reduced average length of the extremities" [MGI:CLS, J:61509] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000556 | abnormal hindlimb morphology | "malformation of the entire posterior extremities" [MGI:tc] |
Show
Allelic Composition: Zeb1tm1.2Mpst/Zeb1tm1.2Mpst
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0000564 | syndactyly | "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0000692 | small spleen | "decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
|
| MP:0000704 | abnormal thymus development | "anomaly in the formation and/or differentiation of the thymus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
|
| MP:0000706 | small thymus | "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167] |
Show
Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
|
| MP:0000714 | increased thymocyte number | "greater than expected number of precursors to T cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Ksr2tm2.1Lex/Ksr2tm2.1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J
|
| MP:0000715 | decreased thymocyte number | "fewer than expected number of precursors to T cells; these cells are lymphoid cells found in the thymus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
|
| MP:0000819 | abnormal olfactory bulb morphology | "malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
|
| MP:0000822 | abnormal brain ventricle morphology | "malformed or absent fluid filled cavities of the cerebrum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.2Yhi/Zeb2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
|
| MP:0000914 | exencephaly | "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.2Yhi/Zeb2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
|
| MP:0000929 | open neural tube | "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.1Yhi/Zeb2tm1.1Yhi,Tg(Zp3-cre)3Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.2Yhi/Zeb2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
|
| MP:0000968 | abnormal sensory neuron innervation | "defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
|
| MP:0001144 | fused vaginal opening | "condition in which the external vaginal opening is closed by the adherence of the epithelium of the vagina" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1+,Zeb2tm1.2Yhi/Zeb2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR
|
| MP:0001260 | increased body weight | "greater than normal average weight " [J:33400] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
|
| MP:0001261 | obese | "excessively fat; an increase in fat in the subcutaneous connective tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: B6.Cg-Zeb1Tw
|
| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
Allelic Composition: Zeb1tm2Yhi/Zeb1+,Zeb2tm1.2Yhi/Zeb2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR
|
| MP:0001270 | distended abdomen | "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
|
| MP:0001312 | abnormal cornea morphology | "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Zeb1tm1Yhi/Zeb1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0001354 | increased aggression towards males | "when compared to controls, subjects exhibit greater than the normal level of domineering, assaultive posture and/or hostile physical action toward male mice" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Webster s II New College Dictionary:ISBN 0-395-70869-9] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0001394 | circling | "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm2Yhi/Zeb1Tw
Genetic Background: B6.Cg-Zeb1tm2Yhi/Zeb1Tw
|
| MP:0001395 | bi-directional circling | "circling behavior exhibited in both clockwise and counterclockwise directions" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: involves: C57BL/6J
|
| MP:0001399 | hyperactivity | "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
|
| MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
Show
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
|
| MP:0001410 | head bobbing | "compulsive up and down movement of the head" [J:17123] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0001431 | abnormal eating behavior | "inability to consume or atypical consumption pattern" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:19212] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1Tw
Genetic Background: B6.Cg-Zeb1tm2Yhi/Zeb1Tw
|
| MP:0001436 | abnormal suckling behavior | "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0001552 | increased circulating triglyceride level | "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
|
| MP:0001554 | increased circulating free fatty acid level | "higher than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
|
| MP:0001575 | cyanosis | "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0001688 | abnormal somite development | "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.1Yhi/Zeb2tm1.1Yhi,Tg(Zp3-cre)3Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
|
| MP:0001730 | embryonic growth arrest | "the cessation of development beyond a particular stage" [J:17509] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1+,Zeb2tm1.2Yhi/Zeb2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR
|
| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0001745 | increased circulating corticosterone level | "greater than the normal concentration of this adrenocortical steroid; induces glycogen deposition and regulates sodium conservation and potassium secretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:54931] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
|
| MP:0001785 | edema | "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065] |
Show
Allelic Composition: Cd83tm1.1Lnjt/Cd83tm1.1Lnjt,March1tm1.1Sish/March1tm1.1Sish
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N
|
| MP:0001805 | decreased IgG | "less than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Ksr2tm2.1Lex/Ksr2tm2.1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J
|
| MP:0001806 | decreased IgM | "less than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Ksr2tm2.1Lex/Ksr2tm2.1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J
|
| MP:0001823 | thymus hypoplasia | "small size due to reduced cell number in the thymus" [J:23255] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
|
| MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
Allelic Composition: Zeb1tm1.2Mpst/Zeb1tm1.2Mpst
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: involves: C57BL/6J
|
| MP:0001924 | infertility | "inability to produce live offspring" [J:47225] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: involves: C57BL/6J
|
| MP:0001953 | respiratory failure | "cessation of or failure to commence breathing" [MGI:cls, J:60159] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Allelic Composition: Zeb1tm1.2Mpst/Zeb1tm1.2Mpst
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0001954 | respiratory distress | "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0002024 | T cell derived lymphoma | "group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0002068 | abnormal parental behavior | "altered behavior of animals towards offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0002079 | increased circulating insulin level | "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
|
| MP:0002116 | abnormal craniofacial bone morphology | "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0002144 | abnormal B lymphocyte development | "atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ksr2tm2.1Lex/Ksr2tm2.1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J
|
| MP:0002145 | abnormal T lymphocyte development | "atypical production of or inability to produce mature T cells, and/or accumulation of T cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
|
| MP:0002151 | abnormal neural tube morphology/development | "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1+,Zeb2tm1.2Yhi/Zeb2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR
|
| MP:0002192 | hydrops fetalis | "an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
Allelic Composition: Zeb1tm1.2Mpst/Zeb1tm1.2Mpst
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0002237 | abnormal nasal cavity morphology | "any structural anomaly of the portion of the respiratory tract that extends from the nares to the pharynx; the nasal cavity is lined with ciliated mucosa" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
|
| MP:0002239 | abnormal nasal septum morphology | "any structural anomaly of the structure that separates the two nasal cavities " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0002244 | abnormal turbinate morphology | "any structural anomaly of the bony plates of the lateral wall of the nasal cavity " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
|
| MP:0002428 | abnormal semicircular canal | "anomaly of the organ of balance composed of three long bony tubes of the labyrinth" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm1.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg
Allelic Composition: Zeb1tm1.1Ajg/Zeb1Tw
Genetic Background: B6.Cg-Zeb1tm1.1Ajg/Zeb1Tw
|
| MP:0002543 | brachyphalangia | "abnormally short phalanges" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Ttpatm1Far/Ttpa+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
|
| MP:0002729 | abnormal canal morphology | "any anomaly or malformation of the tubular ducts of the inner ear" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0002730 | head shaking | "compulsive movement of the head in the horizontal plane" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:274] |
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Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0002820 | abnormal premaxilla morphology | "malformation or absence of the anterior and inner portion of the maxilla" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:76662] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
|
| MP:0002858 | abnormal posterior semicircular canal | "anomaly of the posterior segment of the long bony tube of the labyrinth that is involved in the sense of balance" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0002894 | abnormal otoliths | "malformed crystalline calciferous particles adhering to the otolithic membrane" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, llw2:Linda Washburn , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0002932 | abnormal joint | "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0002978 | absent otoliths | "absence of the crystalline calciferous particles adhering to the otolithic membrane" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0002980 | abnormal postural reflex | "failure to respond with the normal extension of legs to maintain balance when the cage is tilted" [smb:Susan M. Bello , Mouse Genome Informatics Curator, J:88306] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0003051 | curly tail | "a loop or corkscrew-like curl in the tail" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
Allelic Composition: Zeb1tm1.2Mpst/Zeb1tm1.2Mpst
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0003069 | abnormal superior semicircular canal | "anomaly of the upper, superior segment of the long bony tube of the labyrinth that is involved in the sense of balance" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0003143 | enlarged otoliths | "increased average size of the crystalline calciferous particles adhering to the otolithic membrane" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:67072] |
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Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
|
| MP:0003144 | reduced number of otoliths | "decreased average number of the crystalline calciferous particles adhering to the otolithic membrane" [J:30611, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0003148 | reduced cochlear coiling | "a reduction in cochlear coiling or number of turns; in wild-type mice, the cochlea most commonly exhibits one and three-fourth turns" [J:56294, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm1.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg
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| MP:0003161 | absent lateral semicircular canal | |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm1.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg
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| MP:0003162 | reduced size of lateral semicircular canal | |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0003164 | reduced size of posterior semicircular canal | |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm1.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg
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| MP:0003169 | abnormal scala media morphology | "any malformation or absence of the division of the spiral canal of the cochlea that contains the organ of Corti (the neuroepithelial receptor organ for hearing)" [J:23837, J:46972, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0003212 | susceptibility to age related obesity | "increased probability of excessive weight gain that is progressive with age" [RGD:Rat Genome Database submission] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: involves: C57BL/6J
|
| MP:0003419 | delayed endochondral bone ossification | "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0003944 | abnormal T cell subpopulation ratio | "deviation from the standard ratios of T cell subpopulations (e.g. double positive to single positive ratio) compared to control samples" [mberry:Melissa Berry, Genetics Resources Curator] |
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Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
|
| MP:0003949 | abnormal circulating lipid level | "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
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| MP:0004105 | corneal abrasion | "scraping away or denuding of the corneal surface" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0004179 | transmission ratio distortion | "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: involves: C57BL/6J
|
| MP:0004180 | failure of initiation of embryo turning | "failure to begin the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.1Yhi/Zeb2tm1.1Yhi,Tg(Zp3-cre)3Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
|
| MP:0004201 | fetal growth retardation | "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
Allelic Composition: Zeb1tm1.2Mpst/Zeb1tm1.2Mpst
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0004221 | abnormal iridocorneal angle | "any structural abnormality of the acute angle occurring between the iris and the cornea at the periphery of the anterior chamber of the eye" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Zeb1tm1Yhi/Zeb1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0004249 | abnormal crista ampullaris morphology | "anomaly in the elevation found on the inner surface of the ampullae of each semicircular duct; filaments of the vestibular nerve pass through the crista to reach hair cells on its surface; the hair cells are capped by the cupula, a gelatinous protein-polysaccharide mass" [J:60193, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
|
| MP:0004321 | short sternum | "reduced length of the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0004322 | abnormal sternebra morphology | "any structural anomaly of one segments of the primordial sternum of the embryo; these segments fuse to form the body of the adult vertebrate sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0004340 | short scapula | "reduced length of either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0004358 | bowed tibia | "increased curvature of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0004374 | bowed radius | "increased curvature of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0004409 | abnormal neuroepithelium of ampullary crest | "any structural abnormality in the specialized sensory hair cells of the ampullary crest of the ampulla of each semicircular duct" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
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| MP:0004453 | abnormal pterygoid bone morphology | "any structural anomaly of the bone region which corresponds to the inner plate of the pterygoid process of the mammalian skull" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0004477 | turbinate hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, in the small curved bones that extends horizontally along the lateral wall of the nasal passage" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
|
| MP:0004538 | abnormal maxillary shelf | "any structural anomaly of the outgrowth of the maxilla that normally fuses with palatine shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
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| MP:0004596 | abnormal mandibular angle morphology | "any structural anomaly of the portion of the mandible where the body of the mandible (horizontal portion) and the rami (perpendicular portions) meet; these normally unite nearly at right angles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0004642 | fused metatarsal bones | "improper union of the five bones of the hindpaws/feet that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phalanges" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0004681 | intervertebral disk hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the cartilaginous and gelatinous structure found between vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0004686 | decreased length of long bones | "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0004816 | abnormal class switch recombination | "anomaly in the rearrangement of the heavy chain genes of differentiating B cells such that the initially encoded heavy chain IgM molecule is altered to one encoding IgG, IgA or IgE; normally, this allows the body to produce antibodies with different effector functions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
|
| MP:0004883 | abnormal blood vessel healing | "anomaly in the repair process of blood vessels after injury" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0004892 | increased adiponectin level | "greater level of a protein hormone that regulates glucose homeostasis and metabolism of lipids; it is normally produced by adipose tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
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| MP:0004978 | decreased B-1 B cell number | "reduced number of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
|
| MP:0005016 | decreased lymphocyte number | "fewer than normal white blood cell numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
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| MP:0005018 | decreased T cell number | "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
|
| MP:0005092 | decreased double-positive T cell count | "less than the expected number of the subset of T cells found in the thymus that express both CD4 and CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
Show
Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
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| MP:0005093 | impaired B cell proliferation | "absent or reduced ability of B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ksr2tm2.1Lex/Ksr2tm2.1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J
|
| MP:0005104 | abnormal tarsus morphology | "malformation or absence of any of the eight bones of the instep of the paw: tibiale, talus, calcaneus, navicular, 3 cuneiform, and cuboid bones" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
|
| MP:0005163 | cyclopia | "a congenital defect in which the two orbits are united to form a single cavity containing one eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60303] |
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Allelic Composition: Zeb1tm1.2Mpst/Zeb1tm1.2Mpst
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0005170 | cleft lip | "defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
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| MP:0005236 | abnormal olfactory nerve morphology | "anomalous structure of the first cranial nerve, which conveys the sense of smell" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
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| MP:0005290 | decreased oxygen consumption | "less than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
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| MP:0005293 | impaired glucose tolerance | "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
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| MP:0005300 | abnormal corneal stroma morphology | "structural anomaly of the lamellated connective tissue of the cornea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Zeb1tm1Yhi/Zeb1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0005301 | abnormal corneal endothelium morphology | "anomalous structure of the single layer of large flattened cells that cover the surface of the cornea" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0005306 | abnormal phalanx morphology | "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0005324 | ascites | "accumulation or retention of fluid within the peritoneal cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0005331 | insulin resistance | "diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
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| MP:0005336 | abnormal inguinal fat pad | "malformed or aberrant size of the encapsulated adipose tissue found in the groin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:84541] |
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Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
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| MP:0005353 | abnormal patella morphology | "anomalous structure of the large sesamoid bone that covers the anterior surface of the knee" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47316] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0005418 | abnormal circulating hormone level | "anomalous blood concentration of any of the chemical substances that have specific regulatory effects on the activity of a certain organ or organs; originally applied to substances secreted by various endocrine glands and transported in the bloodstream to the target organs, it is sometimes extended to include substances that are not produced by the endocrine glands but that have similar effects" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
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| MP:0005458 | increased percent body fat | "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
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| MP:0005595 | abnormal vascular smooth muscle physiology | "anomalous function of the nonstriated, involuntary muscle tissue of the blood vessels" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0005657 | abnormal neural plate morphology | "malformation or absence of the neuroectodermal area of the embryo s dorsal surface that develops into the neural tube and neural crest" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator, J:68142] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.1Yhi/Zeb2tm1.1Yhi,Tg(Zp3-cre)3Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
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| MP:0005669 | increased circulating leptin level | "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751] |
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Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
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| MP:0006000 | abnormal corneal epithelium | "malformation in the one or more of the layers of epithelial cells covering the front of the cornea" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Ptgs2tm1Unc/Ptgs2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0006012 | dilated endolymphatic duct | "an expansion in the volume of the endolymphatic duct" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:67072:] |
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Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
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| MP:0006092 | abnormal olfactory neuron morphology | "malformation in the neurons that are activated by specific odorants" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92950] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
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| MP:0006207 | embryonic lethality during organogenesis | "death anytime after embryo turning but before the completion of organogenesis (E9 to less than E14)" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.2Yhi/Zeb2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
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| MP:0008045 | decreased NK cell number | "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"] |
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Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
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| MP:0008052 | abnormal serous gland morphology | "any structural anomaly of glands that secrete watery albuminous material that often contains enzymes" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0008079 | decreased CD8-positive T cell number | "reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
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| MP:0008082 | increased single-positive T cell number | "greater number of T cells bearing either CD4 or CD8 markers on their surface" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
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| MP:0008101 | lymph node hypoplasia | "underdevelopment or reduced size, usually due to a reduced cell number, in the lymph nodes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
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| MP:0008168 | decreased B-1a cell number | "reduced number of the B-1 B cell subset bearing the CD5 surface marker" [CL:0000820, PMID:11861604] |
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Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
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| MP:0008170 | decreased B-1b cell number | "reduced number of the B-1 B cell subset not bearing the CD5 surface marker, but having other phenotypic attributes of a B-1 B cell" [CL:0000821, PMID:11861604] |
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Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
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| MP:0008178 | decreased germinal center B cell number | "reduced number of rapidly cycling mature B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA), and are involved in T-dependent immune responses; germinal center B cells are found typically in the germinal centers of lymph nodes and spleen" [CL:0000844, GO:0002314, ISBN:0781735149] |
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Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
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| MP:0008183 | absent marginal zone B cells | "absence of CD23-negative, CD21-positive B cells of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL" [CL:0000845, ISBN:0781735149] |
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Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
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| MP:0008194 | abnormal memory B cell physiology | "abnormal function of a distinctly differentiated long-lived B cell that is readily activated upon reencounter of its antigenic determinant; memory B cells differentiate from antigen-activated B cells which have been selected for expression of higher affinity immunoglobulin" [CL:0000787, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
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| MP:0008488 | abnormal semicircular canal ampulla morphology | "any structural anomaly of the spherical enlargement at the base of each semicircular canal where they connect with the utricle, containing the crista ampullaris which detects movement of the fluid within the canals" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
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| MP:0008495 | decreased IgG1 level | "less than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1m1Btlr/Zeb1m1Btlr
Genetic Background: involves: C57BL/6J
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| MP:0008789 | abnormal olfactory epithelium morphology | "any structural anomaly in the epithelial cells that line the interior of the nose" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
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| MP:0008915 | fused carpal bones | "anomaly of the nine nodular bones of the joint between the forelimb bones and the front paws/hands resulting in some or all the bones being joined together" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0009247 | meteorism | "swelling of the abdomen resulting from gas in the intestinal or peritoneal cavity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
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| MP:0009339 | decreased splenocyte number | "reduction in the expected number of cells of the spleen" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
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| MP:0009655 | abnormal secondary palate development | "any anomaly in the formation of the part of the palate that is formed during embryonic development when palatal projections from the inner part of the maxillary processes emerge, extend and elevate into a horizontal position above the tongue" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:16942766] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
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| MP:0009727 | abnormal navicular morphology | "any structural anomaly of the oval-shaped tarsal bone found between the talus and the 3 cuneiform bones" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0009888 | palatal shelves fail to meet at midline | "polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
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| MP:0009890 | cleft secondary palate | "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0009892 | palate bone hypoplasia | "reduced size of the maxillary or palatine shelves that comprise the bones of the hard palate, usually due to reduced cell number" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0009946 | abnormal olfactory bulb layer morphology | "any structural anomaly of the laminar structure of the forebrain region that coordinates neuronal signaling involved in the perception of smell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
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| MP:0009948 | abnormal olfactory bulb glomerular layer morphology | |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
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| MP:0009951 | abnormal olfactory bulb mitral cell layer morphology | |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
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| MP:0010024 | increased total body fat amount | "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
Allelic Composition: Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
Genetic Background: C57BL/6-Zeb1tm1.1Ajg/Zeb1tm2.1Ajg
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: B6.129P2-Zeb1tm1Yhi
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| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J)
Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: involves: C57BL/6J
Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Zeb1tm1.2Mpst/Zeb1tm1.2Mpst
Genetic Background: involves: C57BL/6 * CBA
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| MP:0011097 | complete embryonic lethality before turning of embryo | "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.1Yhi/Zeb2tm1.1Yhi,Tg(Zp3-cre)3Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
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| MP:0011481 | anterior iris synechia | "adhesion of the iris to the cornea" [MGI:anna] |
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Allelic Composition: Zeb1tm1Yhi/Zeb1tm1Yhi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Zeb1tm1Yhi/Zeb1+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0011732 | decreased somite size | "reduced size of any of the segmental masses along the notochord of the developing embryo" [MGI:smb] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi,Zeb2tm1.1Yhi/Zeb2tm1.1Yhi,Tg(Zp3-cre)3Mrt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR
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| MP:0011939 | increased food intake | "increase in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith] |
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Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
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| MP:0011967 | increased or absent threshold for auditory brainstem response | "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith] |
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Allelic Composition: Zeb1Tw/Zeb1+
Genetic Background: B6.Cg-Zeb1Tw
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| MP:0014012 | abnormal cranial blood vasculature morphology | "any structural anomaly of blood vasculature that is part of a head" [UBERON:0011362] |
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Allelic Composition: Zeb1tm1.2Mpst/Zeb1tm1.2Mpst
Genetic Background: involves: C57BL/6 * CBA
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| MP:0020154 | impaired humoral immune response | "impaired response of the immune system that mediates secreted antibodies produced in B cells" [GOC:NV] |
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Allelic Composition: Tshrm1Btlr/Tshrm1Btlr
Genetic Background: C57BL/6J-Tshrm1Btlr
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| MP:0030259 | mandibular condyloid process hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the mandibular condyloid process" [MGI:anna] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0030285 | mandibular coronoid process hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the thin, flattened, triangular eminence that arises from the upper surface of the mandibular ramus (perpendicular portion)" [MGI:anna] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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| MP:0030304 | abnormal cribriform plate morphology | "any structural anomaly of the sieve-like structure located between the anterior cranial fossa and the nasal cavity; it is a part of the ethmoid bone and supports the olfactory bulb, which lies in the olfactory fossa; it is perforated by foramina for the passage of the olfactory nerves and the anterior ethmoidal nerves to the upper part of the nasal septum, the latter of those to the superior nasal concha" [https://radiopaedia.org/articles/cribriform-plate, MGI:anna] |
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified
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| MP:0030373 | Meckel s cartilage hyperplasia | "overdevelopment or increased size, usually due to an increased number of cells, of the cartilage bar in the mandibular arch that forms a temporary supporting structure in the embryonic mandible and gives rise to middle ear bones and sphenomandibular and anterior malleolar ligaments" [MGI:anna] |
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Allelic Composition: Zeb1tm2Yhi/Zeb1tm2Yhi
Genetic Background: B6.129-Zeb1tm2Yhi
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