ENSMUSG00000024258


Mus musculus

Features
Gene ID: ENSMUSG00000024258
  
Biological name :Polr2d
  
Synonyms : DNA-directed RNA polymerase II subunit RPB4 / Polr2d / Q9D7M8
  
Possible biological names infered from orthology : O15514 / RNA polymerase II subunit D
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: B1
Gene start: 31789159
Gene end: 31796642
  
Corresponding Affymetrix probe sets: 10454478 (MoGene1.0st)   1424258_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025106
NCBI entrez gene - 69241     See in Manteia.
MGI - MGI:1916491
RefSeq - XM_017317977
RefSeq - NM_027002
RefSeq - NM_027101
RefSeq Peptide - NP_081278
swissprot - Q9D7M8
Ensembl - ENSMUSG00000024258
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr2dENSDARG00000076509Danio rerio
 POLR2DENSGALG00000002057Gallus gallus
 O15514ENSG00000144231Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005574  RNA polymerase subunit RPB4/RPC9
 IPR006590  RNA polymerase Rpb4/RPC9, core
 IPR010997  HRDC-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IBA
 biological_processGO:0031990 mRNA export from nucleus in response to heat stress IBA
 biological_processGO:0034402 recruitment of 3"-end processing factors to RNA polymerase II holoenzyme complex IBA
 biological_processGO:0044237 cellular metabolic process IEA
 biological_processGO:0045948 positive regulation of translational initiation IBA
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005665 DNA-directed RNA polymerase II, core complex IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0003727 single-stranded RNA binding IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IBA
 molecular_functionGO:0031369 translation initiation factor binding IBA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Transcriptional regulation by small RNAs
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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