ENSMUSG00000024734


Mus musculus

Features
Gene ID: ENSMUSG00000024734
  
Biological name :Zp1
  
Synonyms : Q62005 / zona pellucida glycoprotein 1 / Zp1
  
Possible biological names infered from orthology : P60852
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 10914287
Gene end: 10920632
  
Corresponding Affymetrix probe sets: 10466091 (MoGene1.0st)   1450306_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025641
Ensembl peptide - ENSMUSP00000128543
NCBI entrez gene - 22786     See in Manteia.
MGI - MGI:103073
RefSeq - NM_009580
RefSeq Peptide - NP_033606
swissprot - F7CW32
swissprot - Q059L1
swissprot - Q62005
Ensembl - ENSMUSG00000024734
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:zfos-1505d6.3ENSDARG00000089966Danio rerio
 zp2.1ENSDARG00000086352Danio rerio
 zp2.2ENSDARG00000105346Danio rerio
 zp2.3ENSDARG00000090237Danio rerio
 zp2.5ENSDARG00000086522Danio rerio
 zp2.6ENSDARG00000091409Danio rerio
 zp2l1ENSDARG00000055415Danio rerio
 zp2l2ENSDARG00000004898Danio rerio
 ZP1ENSG00000149506Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zp2 / P20239 / zona pellucida glycoprotein 2 / Q05996*ENSMUSG0000003091121


Protein motifs (from Interpro)
Interpro ID Name
 IPR000519  P-type trefoil domain
 IPR001507  Zona pellucida domain
 IPR017957  P-type trefoil, conserved site
 IPR017977  Zona pellucida domain, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007338 single fertilization IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IDA


Pathways (from Reactome)
Pathway description
Interaction With The Zona Pellucida


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001130 abnormal ovarian folliculogenesis "atypical formation or failure to form the spherical ovum in the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:35782]
Show

Allelic Composition: Rhbdf2cub/Rhbdf2cub,AregMcub/Areg+
Genetic Background: involves: C57BL/6J * STOCK a us/J * V/LeJ

 MP:0001919 abnormal reproductive system physiology "anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rhbdf2cub/Rhbdf2cub,AregMcub/Areg+
Genetic Background: involves: C57BL/6J * STOCK a us/J * V/LeJ

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Rhbdf2cub/Rhbdf2cub,AregMcub/Areg+
Genetic Background: involves: C57BL/6J * STOCK a us/J * V/LeJ

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rhbdf2cub/Rhbdf2cub,AregMcub/Areg+
Genetic Background: involves: C57BL/6J * STOCK a us/J * V/LeJ

 MP:0003696 abnormal zona pellucida "anomaly or absence of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rhbdf2cub/Rhbdf2cub,AregMcub/Areg+
Genetic Background: involves: C57BL/6J * STOCK a us/J * V/LeJ

 MP:0008868 abnormal granulosa cell morphology "any structural anomaly of a supporting cell for the developing female gamete in the ovary of mammals; granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle" [MESH:A.05.360.319.114.630.535.200]
Show

Allelic Composition: Rhbdf2cub/Rhbdf2cub,AregMcub/Areg+
Genetic Background: involves: C57BL/6J * STOCK a us/J * V/LeJ

 MP:0009375 thin zona pellucida "reduced thickness of the solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rhbdf2cub/Rhbdf2cub,AregMcub/Areg+
Genetic Background: involves: C57BL/6J * STOCK a us/J * V/LeJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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