ENSMUSG00000024991


Mus musculus

Features
Gene ID: ENSMUSG00000024991
  
Biological name :Eif3a
  
Synonyms : Eif3a / Eukaryotic translation initiation factor 3 subunit A / P23116
  
Possible biological names infered from orthology : Q14152
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: D3
Gene start: 60761116
Gene end: 60790693
  
Corresponding Affymetrix probe sets: 10468828 (MoGene1.0st)   1416659_at (Mouse Genome 430 2.0 Array)   1416660_at (Mouse Genome 430 2.0 Array)   1416661_at (Mouse Genome 430 2.0 Array)   1448425_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025955
NCBI entrez gene - 13669     See in Manteia.
MGI - MGI:95301
RefSeq - NM_010123
RefSeq Peptide - NP_034253
swissprot - P23116
Ensembl - ENSMUSG00000024991
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6PCR7ENSDARG00000076815Danio rerio
 ENSGALG00000009328Gallus gallus
 ENSGALG00000041242Gallus gallus
 EIF3AENSG00000107581Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR027512  Eukaryotic translation initiation factor 3 subunit A
 IPR036388  Winged helix-like DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002188 translation reinitiation IBA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0075522 IRES-dependent viral translational initiation IEA
 biological_processGO:0075525 viral translational termination-reinitiation IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0043614 multi-eIF complex IBA
 cellular_componentGO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e IBA
 cellular_componentGO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m IDA
 molecular_functionGO:0003723 RNA binding ISO
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0003743 translation initiation factor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA


Pathways (from Reactome)
Pathway description
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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