ENSMUSG00000025041


Mus musculus

Features
Gene ID: ENSMUSG00000025041
  
Biological name :Nt5c2
  
Synonyms : 5-nucleotidase, cytosolic II / Nt5c2 / Q3V1L4
  
Possible biological names infered from orthology : P49902
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C3
Gene start: 46886831
Gene end: 47015153
  
Corresponding Affymetrix probe sets: 10468253 (MoGene1.0st)   1417201_at (Mouse Genome 430 2.0 Array)   1425933_a_at (Mouse Genome 430 2.0 Array)   1448614_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000084180
Ensembl peptide - ENSMUSP00000129126
Ensembl peptide - ENSMUSP00000130898
Ensembl peptide - ENSMUSP00000134590
NCBI entrez gene - 76952     See in Manteia.
MGI - MGI:2178563
RefSeq - XM_017318312
RefSeq - NM_029810
RefSeq - XM_006527458
RefSeq - XM_006527459
RefSeq - XM_011247398
RefSeq - XM_017318309
RefSeq - XM_017318310
RefSeq - XM_017318311
RefSeq - NM_001164363
RefSeq - NM_001164365
RefSeq Peptide - NP_084086
RefSeq Peptide - NP_001157835
RefSeq Peptide - NP_001157837
swissprot - E9Q9M1
swissprot - Q3V1L4
swissprot - G3UZQ5
swissprot - G3X9J6
Ensembl - ENSMUSG00000025041
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nt5c2aENSDARG00000039399Danio rerio
 nt5c2bENSDARG00000058231Danio rerio
 NT5C2ENSGALG00000008179Gallus gallus
 NT5C2ENSG00000076685Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nt5dc3 / Q3UHB1 / 5-nucleotidase domain-containing protein 3 / Q86UY8* / 5-nucleotidase domain containing 3*ENSMUSG0000005402724
AC152453.1 / NT5DC3* / Q86UY8* / 5-nucleotidase domain containing 3*ENSMUSG0000011274319
Nt5dc2 / 5-nucleotidase domain containing 2 / Q9H857*ENSMUSG0000007154719
Nt5dc1 / Q8C5P5 / 5-nucleotidase domain containing 1 / Q5TFE4*ENSMUSG0000003948016


Protein motifs (from Interpro)
Interpro ID Name
 IPR008380  HAD-superfamily hydrolase, subfamily IG, 5"-nucleotidase
 IPR016695  Purine 5"-nucleotidase
 IPR023214  HAD superfamily
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0046040 IMP metabolic process IBA
 biological_processGO:0046085 adenosine metabolic process IBA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008253 5"-nucleotidase activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Abacavir metabolism
Purine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0009278 abnormal bone marrow cell physiology "any functional anomaly of any of the cells found in the blood" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Nt5c2tm1.1Aafo/Nt5c2+,Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Genetic Background: involves: 129 * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025041 Nt5c2 / Q3V1L4 / 5-nucleotidase, cytosolic II / P49902*  / complex






 

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