ENSMUSG00000025371


Mus musculus

Features
Gene ID: ENSMUSG00000025371
  
Biological name :Chmp6
  
Synonyms : Charged multivesicular body protein 6 / Chmp6 / P0C0A3
  
Possible biological names infered from orthology : Q96FZ7
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 119913441
Gene end: 119919548
  
Corresponding Affymetrix probe sets: 10383282 (MoGene1.0st)   1433684_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026434
Ensembl peptide - ENSMUSP00000117678
Ensembl peptide - ENSMUSP00000116677
Ensembl peptide - ENSMUSP00000114645
NCBI entrez gene - 208092     See in Manteia.
MGI - MGI:3583942
RefSeq - XM_006532718
RefSeq - NM_001085498
RefSeq Peptide - NP_001078967
swissprot - B1AZ39
swissprot - B1AZ41
swissprot - B1AZ42
swissprot - P0C0A3
swissprot - B1AZ40
Ensembl - ENSMUSG00000025371
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chmp6aENSDARG00000097451Danio rerio
 chmp6bENSDARG00000102024Danio rerio
 CHMP6ENSGALG00000026428Gallus gallus
 CHMP6ENSG00000176108Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005024  Snf7 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000920 cell separation after cytokinesis ISO
 biological_processGO:0006997 nucleus organization ISO
 biological_processGO:0007034 vacuolar transport IEA
 biological_processGO:0007080 mitotic metaphase plate congression ISO
 biological_processGO:0007175 negative regulation of epidermal growth factor-activated receptor activity ISO
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0039702 viral budding via host ESCRT complex ISO
 cellular_componentGO:0000815 ESCRT III complex ISO
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0047485 protein N-terminus binding ISO


Pathways (from Reactome)
Pathway description
Macroautophagy
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Cdkn1atm1.1(KOMP)Vlcg/Cdkn1atm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cdkn1atm1.1(KOMP)Vlcg/Ucd

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
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Allelic Composition: Cdkn1atm1.1(KOMP)Vlcg/Cdkn1atm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cdkn1atm1.1(KOMP)Vlcg/Ucd

 MP:0013294 prenatal lethality prior to heart atrial septation "death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb]
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Allelic Composition: Cdkn1atm1.1(KOMP)Vlcg/Cdkn1atm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cdkn1atm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr