ENSMUSG00000025393


Mus musculus

Features
Gene ID: ENSMUSG00000025393
  
Biological name :Atp5b
  
Synonyms : Atp5b / ATP synthase subunit beta, mitochondrial / P56480
  
Possible biological names infered from orthology : ATP5F1B / ATP synthase F1 subunit beta / P06576
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D3
Gene start: 128083273
Gene end: 128090391
  
Corresponding Affymetrix probe sets: 10367106 (MoGene1.0st)   10367118 (MoGene1.0st)   1416829_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026459
NCBI entrez gene - 11947     See in Manteia.
MGI - MGI:107801
RefSeq - NM_016774
RefSeq Peptide - NP_058054
swissprot - P56480
Ensembl - ENSMUSG00000025393
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp5f1bENSDARG00000070083Danio rerio
 ATP5BENSGALG00000038801Gallus gallus
 P06576ENSG00000110955Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000194  ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
 IPR003593  AAA+ ATPase domain
 IPR004100  ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain
 IPR005722  ATP synthase, F1 complex, beta subunit
 IPR020003  ATPase, alpha/beta subunit, nucleotide-binding domain, active site
 IPR024034  ATPase, F1/V1 complex, beta/alpha subunit, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036121  ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006629 lipid metabolic process IMP
 biological_processGO:0006754 ATP biosynthetic process ISO
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration IMP
 biological_processGO:0015986 ATP synthesis coupled proton transport IEA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IEA
 biological_processGO:0046034 ATP metabolic process IEA
 biological_processGO:0051453 regulation of intracellular pH IEA
 biological_processGO:0099132 ATP hydrolysis coupled cation transmembrane transport IEA
 biological_processGO:1902600 proton transmembrane transport IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005753 mitochondrial proton-transporting ATP synthase complex IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0031012 extracellular matrix ISO
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0042645 mitochondrial nucleoid IEA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0045259 proton-transporting ATP synthase complex IEA
 cellular_componentGO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042288 MHC class I protein binding IEA
 molecular_functionGO:0043532 angiostatin binding IEA
 molecular_functionGO:0046933 proton-transporting ATP synthase activity, rotational mechanism ISO
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Formation of ATP by chemiosmotic coupling
Cristae formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001539 decreased number of caudal vertebrae "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Aspatm1b(EUCOMM)Wtsi/Aspatm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Aspatm1b(EUCOMM)Wtsi/Ieg

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr