ENSG00000110955


Homo sapiens

Features
Gene ID: ENSG00000110955
  
Biological name :ATP5F1B
  
Synonyms : ATP5F1B / ATP synthase F1 subunit beta / P06576
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.3
Gene start: 56638175
Gene end: 56646068
  
Corresponding Affymetrix probe sets: 201322_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000262030
Ensembl peptide - ENSP00000446677
Ensembl peptide - ENSP00000447571
Ensembl peptide - ENSP00000448428
Ensembl peptide - ENSP00000446489
NCBI entrez gene - 506     See in Manteia.
OMIM - 102910
RefSeq - NM_001686
RefSeq Peptide - NP_001677
swissprot - V9HW31
swissprot - F8W079
swissprot - F8W0P7
swissprot - H0YH81
swissprot - H0YI37
swissprot - P06576
Ensembl - ENSG00000110955
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp5f1bENSDARG00000070083Danio rerio
 ATP5BENSGALG00000038801Gallus gallus
 Atp5bENSMUSG00000025393Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000194  ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
 IPR003593  AAA+ ATPase domain
 IPR004100  ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain
 IPR005722  ATP synthase, F1 complex, beta subunit
 IPR020003  ATPase, alpha/beta subunit, nucleotide-binding domain, active site
 IPR024034  ATPase, F1/V1 complex, beta/alpha subunit, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036121  ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001649 osteoblast differentiation HDA
 biological_processGO:0006091 generation of precursor metabolites and energy NAS
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006754 ATP biosynthetic process TAS
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration IEA
 biological_processGO:0007005 mitochondrion organization TAS
 biological_processGO:0015986 ATP synthesis coupled proton transport IEA
 biological_processGO:0042407 cristae formation TAS
 biological_processGO:0042776 mitochondrial ATP synthesis coupled proton transport TAS
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IGI
 biological_processGO:0046034 ATP metabolic process IEA
 biological_processGO:0051453 regulation of intracellular pH IMP
 biological_processGO:0099132 ATP hydrolysis coupled cation transmembrane transport IEA
 biological_processGO:1902600 proton transmembrane transport IMP
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005753 mitochondrial proton-transporting ATP synthase complex IDA
 cellular_componentGO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core NAS
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0031966 mitochondrial membrane IDA
 cellular_componentGO:0042645 mitochondrial nucleoid IDA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0045259 proton-transporting ATP synthase complex IDA
 cellular_componentGO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005215 transporter activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IDA
 molecular_functionGO:0022857 transmembrane transporter activity IC
 molecular_functionGO:0042288 MHC class I protein binding IDA
 molecular_functionGO:0043532 angiostatin binding IPI
 molecular_functionGO:0046933 proton-transporting ATP synthase activity, rotational mechanism IMP
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IMP


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Formation of ATP by chemiosmotic coupling
Transcriptional activation of mitochondrial biogenesis
Cristae formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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