ENSMUSG00000025489


Mus musculus

Features
Gene ID: ENSMUSG00000025489
  
Biological name :Ifitm5
  
Synonyms : Ifitm5 / Interferon-induced transmembrane protein 5 / O88728
  
Possible biological names infered from orthology : A6NNB3
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F5
Gene start: 140948958
Gene end: 140950291
  
Corresponding Affymetrix probe sets: 10569011 (MoGene1.0st)   1440216_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026562
NCBI entrez gene - 73835     See in Manteia.
MGI - MGI:1934923
RefSeq - NM_053088
RefSeq Peptide - NP_444318
swissprot - O88728
Ensembl - ENSMUSG00000025489
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ifitm5ENSDARG00000105153Danio rerio
 IFITM5ENSGALG00000004239Gallus gallus
 A6NNB3ENSG00000206013Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm45717 / IFITM2* / IFITM3* / Q01629* / IFITM1* / P13164* / Q01628* / interferon induced transmembrane protein 1* / interferon induced transmembrane protein 2* / interferon induced transmem...ENSMUSG0000011010469
Q9CQW9 / Ifitm3 / Interferon-induced transmembrane protein 3 / IFITM2* / Q01629* / IFITM1* / P13164* / Q01628* / interferon induced transmembrane protein 2* / interferon induced transmembr...ENSMUSG0000002549228
Ifitm7 / interferon induced transmembrane protein 7 / IFITM3* / Q01629* / IFITM1* / IFITM2* / P13164* / Q01628* / interferon induced transmembrane protein 1* / interferon induced transmemb...ENSMUSG0000006596827
Ifitm2 / Q99J93 / Interferon-induced transmembrane protein 2 / IFITM1* / Q01629* / IFITM3* / P13164* / Q01628* / interferon induced transmembrane protein 1* / interferon induced transmembr...ENSMUSG0000006059127
Ifitm6 / IFITM2* / IFITM3* / Q01629* / IFITM1* / P13164* / Q01628* / interferon induced transmembrane protein 1* / interferon induced transmembrane protein 2* / interferon induced transmemb...ENSMUSG0000005910825
Ifitm1 / Q9D103 / Interferon-induced transmembrane protein 1 / IFITM2* / Q01629* / IFITM3* / P13164* / Q01628* / interferon induced transmembrane protein 2* / interferon induced transmembr...ENSMUSG0000002549124
Q8BR26 / Ifitm10 / Mus musculus interferon induced transmembrane protein 10 (Ifitm10), transcript variant 3, mRNA. / A6NMD0* / interferon induced transmembrane protein 10*ENSMUSG0000004577722


Protein motifs (from Interpro)
Interpro ID Name
 IPR007593  CD225/Dispanin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0009607 response to biotic stimulus IEA
 biological_processGO:0030282 bone mineralization IEA
 biological_processGO:0030500 regulation of bone mineralization IEA
 biological_processGO:0060349 bone morphogenesis IMP
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000438 abnormal skull morphology "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0000458 abnormal mandible morphology "malformation of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0002820 abnormal premaxilla morphology "malformation or absence of the anterior and inner portion of the maxilla" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:76662]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0004338 small clavicle "reduced size of one or both of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0004358 bowed tibia "increased curvature of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0004361 bowed ulna "increased curvature of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0004374 bowed radius "increased curvature of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0004686 decreased length of long bones "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0005298 abnormal clavicle morphology "malformation of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0005354 abnormal ilium morphology "structural anomaly of the broad, flaring portion of the hip bone, which is distinct at birth, but later fuses with the ischium and the pubis " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47316]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0030275 thin frontal bone "reduced thickness of the single bone forming the forehead and roof of the eye orbit" [MGI:anna]
Show

Allelic Composition: Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk,Emx1tm1(cre)Ito/Emx1+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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