ENSMUSG00000025491


Mus musculus

Features
Gene ID: ENSMUSG00000025491
  
Biological name :Ifitm1
  
Synonyms : Ifitm1 / Interferon-induced transmembrane protein 1 / Q9D103
  
Possible biological names infered from orthology : IFITM2 / IFITM3 / interferon induced transmembrane protein 2 / interferon induced transmembrane protein 3 / P13164 / Q01628 / Q01629
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F5
Gene start: 140967221
Gene end: 140969825
  
Corresponding Affymetrix probe sets: 10558769 (MoGene1.0st)   10570434 (MoGene1.0st)   1424254_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026564
Ensembl peptide - ENSMUSP00000101655
Ensembl peptide - ENSMUSP00000101657
NCBI entrez gene - 68713     See in Manteia.
MGI - MGI:1915963
RefSeq - XM_006536238
RefSeq - NM_001112715
RefSeq - NM_026820
RefSeq Peptide - NP_081096
RefSeq Peptide - NP_001106186
swissprot - Q9D103
Ensembl - ENSMUSG00000025491
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IFITM3ENSGALG00000026970Gallus gallus
 IFITM1ENSG00000185885Homo sapiens
 IFITM2ENSG00000185201Homo sapiens
 IFITM3ENSG00000142089Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ifitm7 / interferon induced transmembrane protein 7 / IFITM3* / Q01629* / IFITM1* / IFITM2* / P13164* / Q01628* / interferon induced transmembrane protein 1* / interferon induced transmemb...ENSMUSG0000006596874
Q9CQW9 / Ifitm3 / Interferon-induced transmembrane protein 3 / IFITM2* / Q01629* / IFITM1* / P13164* / Q01628* / interferon induced transmembrane protein 2* / interferon induced transmembr...ENSMUSG0000002549271
Ifitm2 / Q99J93 / Interferon-induced transmembrane protein 2 / IFITM1* / Q01629* / IFITM3* / P13164* / Q01628* / interferon induced transmembrane protein 1* / interferon induced transmembr...ENSMUSG0000006059168
Gm45717 / IFITM2* / IFITM3* / Q01629* / IFITM1* / P13164* / Q01628* / interferon induced transmembrane protein 1* / interferon induced transmembrane protein 2* / interferon induced transmem...ENSMUSG0000011010452
Ifitm6 / IFITM2* / IFITM3* / Q01629* / IFITM1* / P13164* / Q01628* / interferon induced transmembrane protein 1* / interferon induced transmembrane protein 2* / interferon induced transmemb...ENSMUSG0000005910847
Q8BR26 / Ifitm10 / Mus musculus interferon induced transmembrane protein 10 (Ifitm10), transcript variant 3, mRNA. / A6NMD0* / interferon induced transmembrane protein 10*ENSMUSG0000004577733
Ifitm5 / O88728 / Interferon-induced transmembrane protein 5 / A6NNB3*ENSMUSG0000002548930


Protein motifs (from Interpro)
Interpro ID Name
 IPR007593  CD225/Dispanin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification IEA
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0009607 response to biotic stimulus IEA
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0030336 negative regulation of cell migration ISS
 biological_processGO:0034341 response to interferon-gamma ISS
 biological_processGO:0035455 response to interferon-alpha ISS
 biological_processGO:0035456 response to interferon-beta ISS
 biological_processGO:0045071 negative regulation of viral genome replication ISS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation ISS
 biological_processGO:0046597 negative regulation of viral entry into host cell IDA
 biological_processGO:0051607 defense response to virus IDA
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000334 decreased granulocyte number "fewer than expected number of leukocytes that have abundant granules in the cytoplasm: basophils, neutrophils, or eosinophils" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Esr1tm4.2Ksk/Esr1tm4.2Ksk
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA

 MP:0001525 impaired balance "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123]
Show

Allelic Composition: Esr1tm4.2Ksk/Esr1tm4.2Ksk
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA

 MP:0002497 increased IgE "greater than normal immunoglobulin class E level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Esr1tm4.2Ksk/Esr1tm4.2Ksk
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA

 MP:0002665 decreased circulating corticosterone level "less than the normal blood concentration of this adrenocortical steroid; induces glycogen deposition and regulates sodium conservation and potassium secretion" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Esr1tm4.2Ksk/Esr1tm4.2Ksk
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA

 MP:0002981 increased liver weight "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Esr1tm4.2Ksk/Esr1tm4.2Ksk
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA

 MP:0003858 enhanced coordination "improved ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Snap25Bdr/Snap25+
Genetic Background: involves: BALB/cAnNCrl

 MP:0005018 decreased T cell number "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Esr1tm4.2Ksk/Esr1tm4.2Ksk
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA

 MP:0005180 abnormal circulating testosterone level "aberration in the blood concentration of this most potent androgen" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Esr1tm4.2Ksk/Esr1tm4.2Ksk
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA

 MP:0005289 increased oxygen consumption "greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Esr1tm4.2Ksk/Esr1tm4.2Ksk
Genetic Background: involves: C57BL/6 * C57BL/6NTac * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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