ENSG00000185201


Homo sapiens

Features
Gene ID: ENSG00000185201
  
Biological name :IFITM2
  
Synonyms : IFITM2 / interferon induced transmembrane protein 2 / Q01629
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p15.5
Gene start: 307631
Gene end: 315272
  
Corresponding Affymetrix probe sets: 201315_x_at (Human Genome U133 Plus 2.0 Array)   214022_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434443
Ensembl peptide - ENSP00000484689
Ensembl peptide - ENSP00000473587
Ensembl peptide - ENSP00000382712
Ensembl peptide - ENSP00000382714
Ensembl peptide - ENSP00000431850
NCBI entrez gene - 10581     See in Manteia.
OMIM - 605578
RefSeq - NM_006435
RefSeq Peptide - NP_006426
swissprot - Q01629
swissprot - H7BYV1
swissprot - H0YCL2
swissprot - E9PQN9
Ensembl - ENSG00000185201
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IFITM3ENSGALG00000026970Gallus gallus
 Gm45717ENSMUSG00000110104Mus musculus
 Ifitm1ENSMUSG00000025491Mus musculus
 Ifitm2ENSMUSG00000060591Mus musculus
 Ifitm3ENSMUSG00000025492Mus musculus
 Ifitm6ENSMUSG00000059108Mus musculus
 Ifitm7ENSMUSG00000065968Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IFITM3 / Q01628 / interferon induced transmembrane protein 3ENSG0000014208991
IFITM1 / P13164 / interferon induced transmembrane protein 1ENSG0000018588565
A6NMD0 / IFITM10 / interferon induced transmembrane protein 10ENSG0000024424236
A6NNB3 / IFITM5 / interferon induced transmembrane protein 5ENSG0000020601331


Protein motifs (from Interpro)
Interpro ID Name
 IPR007593  CD225/Dispanin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0009607 response to biotic stimulus IEA
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0034341 response to interferon-gamma IDA
 biological_processGO:0035455 response to interferon-alpha IDA
 biological_processGO:0035456 response to interferon-beta IDA
 biological_processGO:0045071 negative regulation of viral genome replication IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0046597 negative regulation of viral entry into host cell IDA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060337 type I interferon signaling pathway TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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