ENSMUSG00000025613


Mus musculus

Features
Gene ID: ENSMUSG00000025613
  
Biological name :Cct8
  
Synonyms : Cct8 / chaperonin containing Tcp1, subunit 8 (theta) / P42932
  
Possible biological names infered from orthology : chaperonin containing TCP1 subunit 8 / P50990
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: C3.3
Gene start: 87483326
Gene end: 87495873
  
Corresponding Affymetrix probe sets: 10440600 (MoGene1.0st)   1415785_a_at (Mouse Genome 430 2.0 Array)   1436973_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135377
Ensembl peptide - ENSMUSP00000135651
Ensembl peptide - ENSMUSP00000135830
Ensembl peptide - ENSMUSP00000026704
Ensembl peptide - ENSMUSP00000134920
Ensembl peptide - ENSMUSP00000135498
NCBI entrez gene - 12469     See in Manteia.
MGI - MGI:107183
RefSeq - NM_009840
RefSeq Peptide - NP_033970
swissprot - Q3UL22
swissprot - H3BJB6
swissprot - H3BKG2
swissprot - H3BKR8
swissprot - H3BL49
swissprot - H3BLL1
swissprot - P42932
Ensembl - ENSMUSG00000025613
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cct8ENSDARG00000008243Danio rerio
 CCT8ENSGALG00000015821Gallus gallus
 CCT8ENSG00000156261Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cct8l1 / chaperonin containing TCP1, subunit 8 (theta)-like 1 / CCT8L2* / Q96SF2* / chaperonin containing TCP1 subunit 8 like 2*ENSMUSG0000003804430


Protein motifs (from Interpro)
Interpro ID Name
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012721  T-complex protein 1, theta subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0007339 binding of sperm to zona pellucida IDA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IEA
 biological_processGO:0046931 pore complex assembly IMP
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:1901998 toxin transport IMP
 biological_processGO:1904851 positive regulation of establishment of protein localization to telomere IEA
 biological_processGO:1904871 positive regulation of protein localization to Cajal body IEA
 biological_processGO:1904874 positive regulation of telomerase RNA localization to Cajal body IEA
 cellular_componentGO:0002199 zona pellucida receptor complex IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005832 chaperonin-containing T-complex IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0044297 cell body IDA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IBA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Neutrophil degranulation
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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